Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lucia Kuffová"'
Autor:
Tian Yu, Fabian Schuette, Maria Christofi, John V. Forrester, Gerard J. Graham, Lucia Kuffova
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Herpes stromal keratitis (HSK) is a blinding corneal disease caused by herpes simplex virus-1 (HSV-1), a common pathogen infecting most of the world’s population. Inflammation in HSK is chemokine-dependent, particularly CXCL10 and less so the CC ch
Externí odkaz:
https://doaj.org/article/e71347e3217c42c3a373318cc10d597f
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Immune privilege (IP), a term introduced to explain the unpredicted acceptance of allogeneic grafts by the eye and the brain, is considered a unique property of these tissues. However, immune responses are modified by the tissue in which they occur,
Externí odkaz:
https://doaj.org/article/7ca7cc0d4b914a1fb6c365245a9a75e7
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
The microbiome exerts considerable control over immune homeostasis and influences susceptibility to autoimmune and autoinflammatory disease (AD/AID) such as inflammatory bowel disease (IBD), multiple sclerosis (MS), type 1 diabetes (T1D), psoriasis,
Externí odkaz:
https://doaj.org/article/0cb8a28ec3084732ac2060b4f1f52504
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 140-144 (2019)
Histology (H&E) and transmission electron microscopy (TEM) data are provided showing age-related changes in the retinal structure of sTg-IRBP:HEL mice. These include substantial photoreceptor loss, atrophy of the retinal pigment epithelium, Bruch׳s
Externí odkaz:
https://doaj.org/article/c9ced8249c1948eb9cd83df4c384acc3
Autor:
Yi-Hsia Liu, Christine Mölzer, Kimmo Makinen, Koju Kamoi, Clare L. C. Corbett, Izabela P. Klaska, Delyth M. Reid, Heather M. Wilson, Lucia Kuffová, Richard J. Cornall, John V. Forrester
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We specify the clinical features of a spontaneous experimental autoimmune uveitis (EAU) model, in which foreign hen-egg lysozyme (HEL) is expressed in the retina, controlled by the promoter for interphotoreceptor retinol binding protein (IRBP). We pr
Externí odkaz:
https://doaj.org/article/3369c1a46cdd4c748e1c067e9394d08e
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 185-198 (2018)
Limbal epithelial stem cells (LESCs) are believed to be responsible for corneal epithelial maintenance and repair after injury, but their activity has never been properly quantified in aging or wounded eyes. In this study, labelling with thymidine an
Externí odkaz:
https://doaj.org/article/6a4864883f7a428f9ff70d11d20d565b
Autor:
John V Forrester, Lucia Kuffova
This book provides a summary of the various aspects of corneal transplantation — the clinical, experimental (including multimedia display of the surgical techniques), immunological, therapeutic and prosthetic components — in one volume. The inter
Autor:
Christine Mölzer, Yi-Hsia Liu, Elizabeth Muckersie, Izabela P. Klaska, Richard Cornall, Heather M. Wilson, Lucia Kuffová, John V. Forrester
Undifferentiated uveitis (intraocular inflammation, IOI) is an idiopathic sight-threatening, presumed autoimmune disease, accountable for ~ 10% of all blindness in the developed world. We have investigated the association of uveitis with inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692f08f2de286f401d5c510d42ba6192
https://doi.org/10.21203/rs.3.rs-1776256/v1
https://doi.org/10.21203/rs.3.rs-1776256/v1
Autor:
Denize Atan, Jarka Heissigerova, Lucia Kuffová, Aideen Hogan, Kilmartin, Dara J., Forrester, John V., Bidwell, Jeff L., Dick, Andrew D., Churchill, Amanda J.
Publikováno v:
Molecular Vision
University of Bristol-PURE
University of Bristol-PURE
Purpose Idiopathic intermediate uveitis (IIU) is a potentially sight-threatening inflammatory disorder with well-defined anatomic diagnostic criteria. It is often associated with multiple sclerosis, and both conditions are linked to HLA-DRB1*15. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::04fc9466c9e559167c31a97385b5e18e
http://europepmc.org/articles/PMC3559088
http://europepmc.org/articles/PMC3559088
Autor:
Izabela P. Klaska, Tian Yu, Rosie Fordyce, Koju Kamoi, Richard J. Cornall, Cristina Martin-Granados, Lucia Kuffova, John V. Forrester
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Restoration of immunological tolerance to self antigens has been a major drive in understanding the mechanisms of, and developing new treatments for, autoimmune and autoinflammatory disease. Sessile dendritic cells (DC) are considered the main instru
Externí odkaz:
https://doaj.org/article/15a83eb5a4514cd0bdbba1118b7e9ad2