Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lucia Knopfová"'
Autor:
Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Ondřej Vacek, Jana Pokludová, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody–drug conjugate targeting Trop2 were recently approved for cancer therapy, th
Externí odkaz:
https://doaj.org/article/ec7ff7a2fa694aecb1011c9f0a61909f
Autor:
Monika Dúcka, Martina Kučeríková, Filip Trčka, Jakub Červinka, Elisabetta Biglieri, Jan Šmarda, Lubor Borsig, Petr Beneš, Lucia Knopfová
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 326-336 (2021)
The transcription factor c-Myb can be involved in the activation of many genes with protumorigenic function; however, its role in breast cancer (BC) development is still under discussion. c-Myb is considered as a tumor-promoting factor in the early p
Externí odkaz:
https://doaj.org/article/321b17b6de55437f812950b98e26ab4a
Autor:
Kamila Říhová, Monika Dúcka, Iva Staniczková Zambo, Ladislava Vymětalová, Martin Šrámek, Filip Trčka, Jan Verner, Stanislav Drápela, Radek Fedr, Tereza Suchánková, Barbora Pavlatovská, Eva Ondroušková, Irena Kubelková, Danica Zapletalová, Štěpán Tuček, Peter Múdry, Dagmar Adámková Krákorová, Lucia Knopfová, Jan Šmarda, Karel Souček, Lubor Borsig, Petr Beneš
The transcription factor c-Myb is an oncoprotein promoting cell proliferation and survival when aberrantly activated/expressed, thus contributing to malignant transformation. Overexpression of c-Myb has been found in leukemias, breast, colon and aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b04ff593300ff6bdf0cde2b3cfb8ff
https://www.zora.uzh.ch/id/eprint/226453/
https://www.zora.uzh.ch/id/eprint/226453/
Autor:
Jarmila Navrátilová, Klaus Dreisewerd, Eugene Moskovets, Jens Soltwisch, Michal Hendrych, Lucia Knopfová, Dominika Bezdeková, Jan Preisler, Markéta Machálková, Antonín Bednařík
Publikováno v:
Analytical Chemistry. 92:6245-6250
Visualizing the differential distribution of carbon-carbon double bond (C═C db) positional isomers of unsaturated phospholipids (PL) in tissue sections by use of refined matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI M
Autor:
Tereza Kučírková, Hana Lejdarova, Veronika Oralova, Eva Matalová, Serhiy Forostyak, Petr Kuglík, Zdenek Koristek, Veronika Pospisilova, Ladislava Vymetalova, Eva Makaturova, Lucia Knopfová, Tomas Kasko, Petr Beneš
Publikováno v:
Neurochemical Research. 45:204-214
Neurodegenerative disorders present a broad group of neurological diseases and remain one of the greatest challenges and burdens to mankind. Maladies like amyotrophic lateral sclerosis, Alzheimer's disease, stroke or spinal cord injury commonly featu
Publikováno v:
Cellular Signalling. 100:110476
Autor:
Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody-drug conjugate targeting Trop2 were recently approved cancer therapy, the physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f1ccc011d8be1bda0430a0a7ec71ed
https://doi.org/10.1101/2021.06.29.450320
https://doi.org/10.1101/2021.06.29.450320
Publikováno v:
Physiological Research. :611-622
Effects of low-frequency electromagnetic fields (LF EMF) on the activation of different tissue recovery processes have not yet been fully understood. The detailed quantification of LF EMF effects on the angiogenesis were analysed in our experiments b
Autor:
Petr Beneš, Roman Huley, Monika Dúcka, Taras Gutor, Orest Petronchak, Lucia Knopfová, Lubor Borsig, Nataliya Volodko, Jan Šmarda
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Tumor-associated macrophages (TAMs) are prominent components of tumor stroma that promotes tumorigenesis. Many soluble factors participate in the deleterious cross-talk between TAMs and transformed cells; however mechanisms how tumors orchestrate the
Autor:
Petr Beneš, Jiří Jarkovský, Jana Katolická, Ivan Čapov, Jan Šmarda, Petr Vlček, Tichý M, Markéta Hermanová, Lucia Knopfová
Publikováno v:
Journal of Cancer
Colorectal cancer (CRC) represents a serious challenge for oncologists due to high incidence and large heterogeneity. Prognostic factors are needed to stratify patients according to risk of disease progression. In this study, we report that high expr