Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lucia Hans"'
Autor:
Diana R. Hardie, Howard Newman, Joanna Reid, Nei-Yuan Hsiao, Gert van Zyl, Lucia Hans, Jasantha Odayar, Stephen Korsman
Publikováno v:
African Journal of Laboratory Medicine, Vol 13, Iss 1, Pp e1-e6 (2024)
Background: Understanding factors that impact HIV viral load (VL) accuracy in resource-limited settings is key to quality improvement. Objective: We evaluated whether testing delay and specimen storage between 25 °C and 30 °C before testing affect
Externí odkaz:
https://doaj.org/article/adec96c8a35240e582a6552aa9024c1b
Autor:
Lucia Hans, Naseem Cassim, Somayya Sarang, Diana Hardie, Silence Ndlovu, W.D. Francois Venter, Pedro Da Silva, Wendy Stevens
Publikováno v:
Diagnostics, Vol 13, Iss 17, p 2731 (2023)
HIV viral load (VL) testing plays a key role in the clinical management of HIV as a marker of adherence and antiretroviral efficacy. To date, national and international antiretroviral treatment recommendations have evolved to endorse routine VL testi
Externí odkaz:
https://doaj.org/article/98e894e1bdf2470da9f6c13702eb50cb
Autor:
Lesley Erica Scott, Nei-yuan Hsiao, Graeme Dor, Lucia Hans, Puleng Marokane, Manuel Pedro da Silva, Wolfgang Preiser, Helena Vreede, Jonathan Tsoka, Koleka Mlisana, Wendy Susan Stevens
Publikováno v:
Diagnostics, Vol 13, Iss 15, p 2554 (2023)
The high demand for SARS-CoV-2 tests but limited supply to South African laboratories early in the COVID-19 pandemic resulted in a heterogenous diagnostic footprint of open and closed molecular testing platforms being implemented. Ongoing monitoring
Externí odkaz:
https://doaj.org/article/a4c1734e8abc45f2a8e4ecac66c74752
Autor:
Kim Steegen, Gert U. van Zyl, Mathilda Claassen, Aabida Khan, Melendhran Pillay, Subitha Govender, Phillip A. Bester, Johanna M. van Straaten, Vibha Kana, Ewaldé Cutler, Monalisa N. Kalimashe, Ramokone L. Lebelo, Mokopi B. H. Moloi, Lucia Hans
Publikováno v:
Diagnostics, Vol 13, Iss 13, p 2209 (2023)
Monitoring of HIV drug resistance (HIVDR) remains critical for ensuring countries attain and sustain the global goals for ending HIV as a public health threat by 2030. On an individual patient level, drug resistance results assist in ensuring unneces
Externí odkaz:
https://doaj.org/article/fd7c7c92a9a2403ca4997f1fde063b85
Autor:
Lucia Hans, Kim Steegen, Irene Ketseoglou, Zukiswa Mahlumba, Naseem Cassim, Tracey Wiggill, W.D. Francois Venter, Wendy Stevens
Publikováno v:
International Journal of Infectious Diseases, Vol 110, Iss , Pp 1-3 (2021)
Africa’s readiness to respond to the SARS-COV-2 pandemic was tested due to reliance on rapid turn-around-time of polymerase chain reaction results for clinical management, isolation and quarantine decisions. The NHLS HIV Molecular Laboratory in Joh
Externí odkaz:
https://doaj.org/article/879d58d5719c4afd9932104df2f4f19f
Autor:
Lara Dominique Noble, Lesley Erica Scott, Riffat Munir, Mignon Du Plessis, Kim Steegen, Lucia Hans, Puleng Marokane, Pedro Da Silva, Wendy Susan Stevens
Publikováno v:
Diagnostics, Vol 13, Iss 1, p 34 (2022)
The Xpert® Xpress SARS-CoV-2 and Xpert® Xpress SARS-CoV-2/Flu/RSV tests were rapidly developed and widely used during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. In response to emerging genetic variability, a new SARS
Externí odkaz:
https://doaj.org/article/a7cf10e589ce4ba4afc7de91b5541f24
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232345 (2020)
BACKGROUND:In remote settings, timely plasma separation and transportation to testing laboratories is an impediment to the access of HIV viral load (VL) testing. Potential solutions are whole blood testing through point of care (POC) assays or dried
Externí odkaz:
https://doaj.org/article/d2019884b370496393a79926752c24d4
Publikováno v:
AIDS. 37:1009-1011
Publikováno v:
Pediatric Infectious Disease Journal. 41:827-834
Fixed-dose combination of dolutegravir (DTG) with tenofovir disoproxil fumarate (TDF) and lamivudine (3TC) likely improves adherence and has a favorable resistance profile. We evaluated predicted efficacy of TLD (TDF-3TC-DTG) in children and adolesce
Autor:
Riffat Munir, Lesley Erica Scott, Lara Dominique Noble, Kim Steegen, Lucia Hans, Wendy Susan Stevens
Publikováno v:
Microbiology Spectrum. 11
Laboratory diagnosis plays an important role in curbing the transmission of infection and reducing harmful delays in clinical and public health responses. Alternatives to the current standard of care assays for SARS-CoV-2 are important in order to ov