Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lucia Formicola"'
Autor:
Xavier Maréchal, Sandrine Ongeri, Nicolas Basse, Thierry Milcent, Danièle Bonnet-Delpon, Michèle Reboud-Ravaux, Lucia Formicola, Michelle Bouvier-Durand
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:83-86
We have designed novel small inhibitors of rabbit 20S proteasome using a trifluoromethyl-β-hydrazino acid scaffold. Structural variations influenced their inhibition of the three types of active sites. Proteasome inhibition at the micromolar level w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597def17cfbfaccd18c9e4737f57e43a
https://doi.org/10.1016/j.bmcl.2008.11.012
https://doi.org/10.1016/j.bmcl.2008.11.012
Autor:
Andrea Bordessa, Massaba Keita, Jean-Louis Soulier, Cyril Bauvais, Sandrine Ongeri, Lucia Formicola, Guillaume Bernadat, Michèle Reboud-Ravaux, Benoit Crousse, Jordi Rodrigo, Laure Dufau, Thierry Milcent, Nathalie Lagarde, Xavier Maréchal
Publikováno v:
European journal of medicinal chemistry. 70
We describe the synthesis of a library of new pseudopeptides and their inhibitory activity of the rabbit 20S proteasome chymotrypsin-like (ChT-L) activity. We replaced a natural α-amino acid by an α- or a β-hydrazino acid and obtained inhibitors o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4127f774108bf5c6e9d2b64fa5a4025
https://pubmed.ncbi.nlm.nih.gov/24185380
https://pubmed.ncbi.nlm.nih.gov/24185380