Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Lucia Desser"'
1
Stimulation of Reactive Oxygen Species Production and Cytotoxicity in Human Neutrophilsin vitroand after Oral Administration of a Polyenzyme Preparation
Autor: Eva Zavadova, Thomas Mohr, Lucia Desser
Publikováno v: Cancer Biotherapy. 10:147-152
Polymorphonuclear neutrophils (PMN) can be primed for enhanced release of reactive oxygen species (ROS) by exposure to cytokines and biological response modifiers. ROS are considered to possess tumoricidal activity. The polyenzyme preparation Wobenzy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530dba0e368baa5e937f483f02e58da5
https://doi.org/10.1089/cbr.1995.10.147
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2
Cytokine Synthesis in Human Peripheral Blood Mononuclear Cells after Oral Administration of Polyenzyme Preparations
Autor: Elise Kokron, Alexander Rehberger, Walter Paukovits, Lucia Desser
Publikováno v: Oncology. 50:403-407
Pharmaceutical preparations containing mixtures of various proteolytic and nonproteolytic enzymes have been suggested for use in the treatment of malignant diseases. However, the mode of action of such preparations was not clear. We have shown before
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672f61f23abf259092f7d2edccea9cb3
https://doi.org/10.1159/000227219
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3
Contents, Vol. 50, 1993
Autor: Giuseppe Ricciardi, P.F. Conte, Masaharu Yoshihara, J. Limon, T. Jørgensen, B.E. Christensen, Sachio Fushida, Motofumi Yoshida, Ikuo Takahashi, Keizo Sugimachi, Koji Sumii, J. Schädelin, Claudio Rolim Teixeira, Enrico Colli, H. Hasle, D. Gardiner, Masahito Sugimura, Vittorio Gebbia, Salvatore Restivo, S. Barni, H. Birgens, M.A. Nagai, C.H. Wilder-Smith, A. Drivsholm, Yasunori Emi, Demetrios Minaretzis, M. Hrženjak, O.H.G. Wilder-Smith, Giuseppe Del Favero, Antonio Testa, M.M. Brentani, N.E. Hansen, Fabio Parazzini, Daniel Mordochovich, G. Seitz, Michael D. Melekos, L.A. Marques, G Cannata, M.M. Hansen, P. Lissoni, P.M. Suter, A. Borgeat, Yutaka Yonemura, Fumio Shimamoto, C Ferrara, M. Boogaerts, Daniela Basso, N. Blin, N.A. Peterslund, Elise Kokron, Mario Plebani, V. Jønsson, I. Kardaś, Noboru Konishi, Giovanni Spadafora, Yoshio Hiasa, Luca Tozzi, N. Žarković, Walter Paukovits, Lucia Desser, M. Forni, G.J.M. Maestroni, Tetsuya Kusumoto, S. Taesch, Francesco Mangano, Paola Fogar, M. Jurin, Bosco Lopez Saez, Z. Ilić, A. Rubagotti, Hiroto Nishioka, Roberto Valenza, J. Nikoskelainen, A. Ardizzoia, Marco Scatigna, Shinji Tanaka, Giuseppe Zerillo, Tamara Meggiato, Alexander Rehberger, Nicola Gebbia, Kouichiro Tsugawa, C. Welter, A. Niezabitowski, Gianfranco Cupido, A. Ferrant, Yoshiteru Kitahori, Diana Rinkevitch, Yehudith Ben-Arieh, Isao Hayashi, Federico Ingria, A. Conti, Ken Haruma, G. Gardin, Khalida P. Salim, Lael Best, Shunji Kohnoe, Shad S. Akhtar, I. Sklenar, G. Verhoef, D. Aravantinos, Goro Kajiyama, Walter Markiewicz, G. Schiffman, K.D. Christensen, Carmelo Barbaccia, R. Rosso, G. Bertelli, Angelo Burlina, G. Tancini, Stylianos Michalas, Zareefa A. Bano, G. Towse, Rebsdorf Pedersen, H. Torloni, Christina Tsionou, P. Pronzato, Antonis Keramopoulos, Yoshihiko Maehara, J. Ryś, Senra Varela, F. Rovelli, R. Lahtinen
Publikováno v: Oncology. 50:I-VI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0a1cf8df5397552c9bdce4fb5e699d0
https://doi.org/10.1159/000227216
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5
Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood
Autor: Irene Herbacek, Holománová D, Eva Zavadova, Karel Pavelka, Thomas Mohr, Lucia Desser
Publikováno v: Scopus-Elsevier
Therapy with oral proteolytic enzymes (OET) with combination drug products containing papain, bromelain, trypsin, and chymotrypsin has been shown to be beneficial in clinical settings such as radiotherapy-induced fibrosis, bleomycin pneumotoxicity an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a7814e1c0bd02aea5fc3e9f2d5bb67
https://pubmed.ncbi.nlm.nih.gov/11561866
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6
Proteolytic enzymes and amylase induce cytokine production in human peripheral blood mononuclear cells in vitro
Autor: Alexander Rehberger, Walter Paukovits, Lucia Desser
Publikováno v: Cancer biotherapy. 9(3)
In vitro treatment of human peripheral blood mononuclear cells (PBMNC) with proteolytic enzymes (bromelain, papain) and amylase leads to the production of large amounts of tumor necrosis factor-alpha (TNF-alpha), interleukin-1-beta (IL-1 beta), and i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee959995c12220e04e4d4aa4566533f7
https://pubmed.ncbi.nlm.nih.gov/7529614
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7
Induction of tumor necrosis factor in human peripheral-blood mononuclear cells by proteolytic enzymes
Autor: Alexander Rehberger, Lucia Desser
Publikováno v: Oncology. 47(6)
We could demonstrate that polyenzyme preparations as well as bromelain and papain stimulate the production of tumor necrosis factor-alpha in human peripheral-blood mononuclear cell cultures in a time-dependent manner. We give evidence that immunomodu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bd70259ec9dc0a108eb87855f6c14a
https://pubmed.ncbi.nlm.nih.gov/2243666
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8
587 Modulation of Human Malignant effusion—derived macrophages by cytokines
Autor: E. Hauptmann, Michael Micksche, H. Salzer, E. Pedram, S. Maca, M. Neumann, Eva Zavadova, Lucia Desser
Publikováno v: European Journal of Cancer. 31:S124-S125
The role of tumor-associated macrophages (TAM) as potential effector cells for eradicating malignant cells is not yet entirely clarified. In the present study TAM were isolated from malignant effusions of ovarian, breast and lung cancer patients by g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38a1ae8fe29b58af432ee6b2afb124aa
https://doi.org/10.1016/0959-8049(95)95841-s
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