Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lucia Cilenti"'
Autor:
Lucia Cilenti, Jacopo Di Gregorio, Rohit Mahar, Fei Liu, Camilla T. Ambivero, Muthu Periasamy, Matthew E. Merritt, Antonis S. Zervos
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Obesity is a growing epidemic affecting millions of people worldwide and a major risk factor for a multitude of chronic diseases and premature mortality. Accumulating evidence suggests that mitochondria have a profound role in diet-induced obesity an
Externí odkaz:
https://doaj.org/article/4e9129dc645344a9b0a8a2258082e805
Autor:
Lucia Cilenti, Rohit Mahar, Jacopo Di Gregorio, Camilla T. Ambivero, Matthew E. Merritt, Antonis S. Zervos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
MUL1 is a multifunctional E3 ubiquitin ligase that is involved in various pathophysiological processes including apoptosis, mitophagy, mitochondrial dynamics, and innate immune response. We uncovered a new function for MUL1 in the regulation of mitoc
Externí odkaz:
https://doaj.org/article/836e49a91fde481ba036d80a3b8bea90
Autor:
Albert Serrano, Xin Qiao, Jason O. Matos, Lauren Farley, Lucia Cilenti, Bo Chen, Suren A. Tatulian, Ken Teter
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Aggregates of α-synuclein contribute to the etiology of Parkinson’s Disease. Protein disulfide isomerase (PDI), a chaperone and oxidoreductase, blocks the aggregation of α-synuclein. An S-nitrosylated form of PDI that cannot function as a chapero
Externí odkaz:
https://doaj.org/article/2d251f86f84b4b4ea4970e424a2bfcff
Publikováno v:
Cellular microbiologyREFERENCES. 23(11)
Many Gram-negative pathogens produce a cytolethal distending toxin (CDT) with two cell-binding subunits (CdtA + CdtC) and a catalytic CdtB subunit. After adhesion to the plasma membrane of a target cell, CDT moves by retrograde transport to endoplasm
Autor:
Jacopo, Di Gregorio, Lucia, Cilenti, Camilla T, Ambivero, Thomas, Andl, Ronglih, Liao, Antonis S, Zervos
Publikováno v:
Biochim Biophys Acta Mol Cell Res
UBXN7 is a cofactor protein that provides a scaffold for both CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes involved in the regulation of the NRF2 and HIF-1α protein levels respectively. NRF2 and HIF-1α are surveillance transcription factors
Autor:
Xin Qiao, Lauren Farley, Lucia Cilenti, Bo Chen, Albert Serrano, Suren A. Tatulian, Jason O. Matos, Ken Teter
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Aggregates of α-synuclein contribute to the etiology of Parkinson's Disease. Protein disulfide isomerase (PDI), a chaperone and oxidoreductase, blocks the aggregation of α-synuclein. An S-nitrosylated form of PDI that cannot function as a chaperone
Autor:
Thomas Andl, Ronglih Liao, Jacopo Di Gregorio, Lucia Cilenti, Antonis S. Zervos, Camilla T. Ambivero
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
MUL1 is a multifunctional E3 ubiquitin ligase anchored in the outer mitochondrial membrane with its RING finger domain facing the cytoplasm. MUL1 participates in various biological pathways involved in apoptosis, mitochondrial dynamics, and innate im
Autor:
Thomas Andl, Antonis S. Zervos, Lucia Cilenti, Jacopo Di Gregorio, Ronglih Liao, Camilla T. Ambivero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1868:118963
UBXN7 is a cofactor protein that provides a scaffold for both CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes involved in the regulation of the NRF2 and HIF-1α protein levels respectively. NRF2 and HIF-1α are surveillance transcription factors tha
Autor:
Nicholas Ciaffone, Suren A. Tatulian, Laurene Tetard, Qing X. Wang, Lucia Cilenti, Greg Goldblatt, Briana Lee, Ken Teter, Jason O. Matos
Publikováno v:
The FEBS Journal. 284:1355-1369
Amyloid β (Aβ) peptide plays a major role in Alzheimer's disease (AD) and occurs in multiple forms, including pyroglutamylated Aβ (AβpE). Identification and characterization of the most cytotoxic Aβ species is necessary for advancement in AD dia
Publikováno v:
The FASEB Journal. 33