Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Lucia Ciccoli"'
Autor:
Silvia Leoncini, Cinzia Signorini, Lidia Boasiako, Valeria Scandurra, Joussef Hayek, Lucia Ciccoli, Marcello Rossi, Roberto Canitano, Claudio De Felice
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundBreathing abnormalities are common in Rett syndrome (RTT), a pervasive neurodevelopmental disorder almost exclusively affecting females. RTT is linked to mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. Our aim was to assess the
Externí odkaz:
https://doaj.org/article/fd2e5538d6c6424f90cd1436eea23b25
Autor:
Cinzia Signorini, Silvia Leoncini, Thierry Durand, Jean-Marie Galano, Alexandre Guy, Valérie Bultel-Poncé, Camille Oger, Jetty Chung-Yung Lee, Lucia Ciccoli, Joussef Hayek, Claudio De Felice
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4240 (2021)
Neuroprostanes, a family of non-enzymatic metabolites of the docosahexaenoic acid, have been suggested as potential biomarkers for neurological diseases. Objective biological markers are strongly needed in Rett syndrome (RTT), which is a progressive
Externí odkaz:
https://doaj.org/article/42f9fbca88304d4cb28720560726d260
Autor:
Alessio Cortelazzo, Claudio De Felice, Bianca De Filippis, Laura Ricceri, Giovanni Laviola, Silvia Leoncini, Cinzia Signorini, Monica Pescaglini, Roberto Guerranti, Anna Maria Timperio, Lello Zolla, Lucia Ciccoli, Joussef Hayek
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Rett syndrome (RTT) is a rare neurodevelopmental disorder usually caused by mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2). Several Mecp2 mutant mouse lines have been developed recapitulating part of the clinical features. In par
Externí odkaz:
https://doaj.org/article/7ad46a269f634268b950c94bd4ae5cef
Autor:
Claudio De Felice, Floriana Della Ragione, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Lucia Ciccoli, Francesco Scalabrì, Federico Marracino, Michele Madonna, Giuseppe Belmonte, Laura Ricceri, Bianca De Filippis, Giovanni Laviola, Giuseppe Valacchi, Thierry Durand, Jean-Marie Galano, Camille Oger, Alexandre Guy, Valérie Bultel-Poncé, Jacky Guy, Stefania Filosa, Joussef Hayek, Maurizio D'Esposito
Publikováno v:
Neurobiology of Disease, Vol 68, Iss , Pp 66-77 (2014)
Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively females, caused in the overwhelming majority of the cases by loss-of-function mutations in the gene encoding methyl-CpG binding protein 2 (MECP2). High circulating
Externí odkaz:
https://doaj.org/article/f05bc40df8d64a928adb14bd5f3ac97e
Autor:
Cinzia Signorini, Claudio De Felice, Silvia Leoncini, Rikke S Møller, Gloria Zollo, Sabrina Buoni, Alessio Cortelazzo, Roberto Guerranti, Thierry Durand, Lucia Ciccoli, Maurizio D'Esposito, Kirstine Ravn, Joussef Hayek
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150101 (2016)
Rett syndrome (RTT) and MECP2 duplication syndrome (MDS) are neurodevelopmental disorders caused by alterations in the methyl-CpG binding protein 2 (MECP2) gene expression. A relationship between MECP2 loss-of-function mutations and oxidative stress
Externí odkaz:
https://doaj.org/article/a25ffdc1971a40308ba4f98e5c814c60
Autor:
Claudio De Felice, Cinzia Signorini, Thierry Durand, Camille Oger, Alexandre Guy, Valérie Bultel-Poncé, Jean-Marie Galano, Lucia Ciccoli, Silvia Leoncini, Maurizio D'Esposito, Stefania Filosa, Alessandra Pecorelli, Giuseppe Valacchi, Joussef Hayek
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2287-2297 (2011)
Oxidative damage has been reported in Rett syndrome (RTT), a pervasive developmental disorder caused in up to 95% of cases by mutations in the X-linked methyl-CpG binding protein 2 gene. Herein, we have synthesized F2-dihomo-isoprostanes (F2-dihomo-I
Externí odkaz:
https://doaj.org/article/4361ec52bf0e41b8aeb2fdf22674420b
Autor:
Cinzia Signorini, Claudio De Felice, Jean-Marie Galano, Camille Oger, Silvia Leoncini, Alessio Cortelazzo, Lucia Ciccoli, Thierry Durand, Joussef Hayek, Jetty Chung-Yung Lee
Publikováno v:
Antioxidants, Vol 7, Iss 7, p 88 (2018)
Isoprostanoids are a large family of compounds derived from non-enzymatic oxidation of polyunsaturated fatty acids (PUFAs). Unlike other oxidative stress biomarkers, they provide unique information on the precursor of the targeted PUFA. Although they
Externí odkaz:
https://doaj.org/article/f466414f146b46c493b33e16c6d5f5f9
Autor:
Alessio Cortelazzo, Claudio De Felice, Roberto Guerranti, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Gloria Zollo, Claudia Landi, Giuseppe Valacchi, Lucia Ciccoli, Luca Bini, Joussef Hayek
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Inflammation has been advocated as a possible common central mechanism for developmental cognitive impairment. Rett syndrome (RTT) is a devastating neurodevelopmental disorder, mainly caused by de novo loss-of-function mutations in the gene encoding
Externí odkaz:
https://doaj.org/article/0c0d4dfcf23c4057aa94668d0f00d6eb
Autor:
Silvia Maffei, Claudio De Felice, Pierpaolo Cannarile, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Barbara Montomoli, Stefano Lunghetti, Lucia Ciccoli, Thierry Durand, Roberto Favilli, Joussef Hayek
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Rett syndrome (RTT) is a devastating neurodevelopmental disorder with a 300-fold increased risk rate for sudden cardiac death. A subclinical myocardial biventricular dysfunction has been recently reported in RTT by our group and found to be associate
Externí odkaz:
https://doaj.org/article/349b39da1d714ddaa80fab24aaefd21f
Autor:
Claudio De Felice, Marcello Rossi, Silvia Leoncini, Glauco Chisci, Cinzia Signorini, Giuseppina Lonetti, Laura Vannuccini, Donatella Spina, Alessandro Ginori, Ingrid Iacona, Alessio Cortelazzo, Alessandra Pecorelli, Giuseppe Valacchi, Lucia Ciccoli, Tommaso Pizzorusso, Joussef Hayek
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/72deeeb69f864042b7c05f24fee72074