Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Lucia Carboni"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7702-7718 (2024)
The IgLON family of cell adhesion molecules consists of five members (LSAMP, OPCML, neurotrimin, NEGR1, and IgLON5) discovered as supporters of neuronal development, axon growth and guidance, and synapse formation and maintenance. Tumour suppression
Externí odkaz:
https://doaj.org/article/da0e2c5e57fb4fc0a9262a5b904284a1
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Alzheimer’s disease is the most common form of dementia. Notwithstanding the huge investments in drug development, only one disease-modifying treatment has been recently approved. Here we present a single-cell-led systems biology pipeline
Externí odkaz:
https://doaj.org/article/782197ecf79140258cdbfbd1725f622f
Autor:
Mahnaz Mansouri, Leopold Kremser, Thanh-Phuong Nguyen, Yu Kasugai, Laura Caberlotto, Martin Gassmann, Bettina Sarg, Herbert Lindner, Bernhard Bettler, Lucia Carboni, Francesco Ferraguti
Publikováno v:
Cells, Vol 12, Iss 9, p 1325 (2023)
The metabotropic glutamate receptor 1 (mGlu1) plays a pivotal role in synaptic transmission and neuronal plasticity. Despite the fact that several interacting proteins involved in the mGlu1 subcellular trafficking and intracellular transduction mecha
Externí odkaz:
https://doaj.org/article/1fc6d52602db4e149a31891afc01bb64
Autor:
Francesca Felicia Caputi, Lucia Carboni, Laura Rullo, Irene Alessandrini, Eleonora Balzani, Rita Maria Melotti, Patrizia Romualdi, Sanzio Candeletti, Andrea Fanelli
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
This study aimed to investigate DNA methylation levels in patients undergoing major breast surgery under opioid-based general anesthesia. Blood samples were collected from eleven enrolled patients, before, during and after anesthesia. PBMC were isola
Externí odkaz:
https://doaj.org/article/50cc6a307d4442adb156e62fec39b961
Autor:
Lucia Carboni, Francesca Pischedda, Giovanni Piccoli, Mario Lauria, Laura Musazzi, Maurizio Popoli, Aleksander A. Mathé, Enrico Domenici
Publikováno v:
Cells, Vol 9, Iss 8, p 1818 (2020)
The Negr1 gene has been significantly associated with major depression in genetic studies. Negr1 encodes for a cell adhesion molecule cleaved by the protease Adam10, thus activating Fgfr2 and promoting neuronal spine plasticity. We investigated wheth
Externí odkaz:
https://doaj.org/article/b710ceba685e41a8bb69fd050762a2af
Autor:
Ekaterini Blaveri, Fiona Kelly, Alessandra Mallei, Kriss Harris, Adam Taylor, Juliet Reid, Maria Razzoli, Lucia Carboni, Chiara Piubelli, Laura Musazzi, Girogio Racagni, Aleksander Mathé, Maurizio Popoli, Enrico Domenici, Stewart Bates
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12596 (2010)
The Flinders model is a validated genetic rat model of depression that exhibits a number of behavioural, neurochemical and pharmacological features consistent with those observed in human depression.In this study we have used genome-wide microarray e
Externí odkaz:
https://doaj.org/article/0d06e0f559d34e25b529e77c0e39043b
Autor:
Lucia Carboni, Laura Rullo, Francesca Felicia Caputi, Serena Stamatakos, Sanzio Candeletti, Patrizia Romualdi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14041
Trazodone is an efficacious atypical antidepressant acting both as an SSRI and a 5HT2A and 5HT2C antagonist. Antagonism to H1-histaminergic and alpha1-adrenergic receptors is responsible for a sleep-promoting action. We studied long-term gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f8deeb43104cc78e0e21be9cc5a331
https://pubmed.ncbi.nlm.nih.gov/36430520
https://pubmed.ncbi.nlm.nih.gov/36430520
Publikováno v:
European Neuropsychopharmacology. 57:1-14
Anxiety disorders are pervasive psychiatric disorders causing great suffering. The high (HAB) and low (LAB) anxiety-related behaviour rats were selectively bred to investigate neurobiological correlates of anxiety. We compared the level of neuropepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb684954d947c3d3a82352f4c531bc7
https://doi.org/10.1016/j.euroneuro.2021.12.011
https://doi.org/10.1016/j.euroneuro.2021.12.011
The association between Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) has been extensively demonstrated, but despite this, the pathophysiological mechanisms underlying it are still unknown. In previous work, we discovered a central r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7732c0d971bbec968a4ad9ae9fa0fc35
https://hdl.handle.net/11562/1087733
https://hdl.handle.net/11562/1087733
Publikováno v:
Scientific reports. 13(1)
Alzheimer’s disease is the most common form of dementia. Notwithstanding the huge investments in drug development, only one disease-modifying treatment has been recently approved. Here we present a single-cell-led systems biology pipeline for the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67c2c70056de3a4ed17b37834ca06b6
https://pubmed.ncbi.nlm.nih.gov/36604493
https://pubmed.ncbi.nlm.nih.gov/36604493