Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lucia Cabal Hierro"'
Autor:
Ricardo Larrainzar-Garijo, Esther Fernández-Tormos, Carlos Alberto Collado-Escudero, María Alcantud Ibáñez, Fernando Oñorbe-San Francisco, Judith Marin-Corral, David Casadevall, David Donaire-Gonzalez, Luisa Martínez-Sanchez, Lucia Cabal-Hierro, Diego Benavent, Fátima Brañas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Hip fractures (HFx) are associated with a higher morbidity and mortality rates, leading to a significant reduction in life quality and in limitation of patient´s mobility. The present study aimed to obtain real-world evidence on the clinica
Externí odkaz:
https://doaj.org/article/72a4b825900347b28f139e6d05187f37
Autor:
Lucia Cabal-Hierro, Peter van Galen, Miguel A. Prado, Kelly J. Higby, Katsuhiro Togami, Cody T. Mowery, Joao A. Paulo, Yingtian Xie, Paloma Cejas, Takashi Furusawa, Michael Bustin, Henry W. Long, David B. Sykes, Steven P. Gygi, Daniel Finley, Bradley E. Bernstein, Andrew A. Lane
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Chromatin accessibility is a key mediator of gene expression and mutations in chromatin modifiers are frequently seen in cancers. Here, the authors show that the chromatin accessibility regulator HMGN1 - which is frequently mutated by amplification i
Externí odkaz:
https://doaj.org/article/f424d9b406fb49f7a429fe6474f60a2d
Autor:
Andrew A. Lane, H. Phillip Koeffler, Omar Abdel-Wahab, Francine Garnache-Ottou, Naveen Pemmaraju, Marina Konopleva, Henry Yang, Peter S. Hammerman, David M. Weinstock, Pier Paolo Piccaluga, Fabrice Jardin, Elizabeth A. Morgan, Abner Louissaint, Scott B. Lovitch, Silvia Buonamici, Michael Seiler, Sabeha Biichle, Fanny Angelot-Delettre, Yvonne Y. Li, Jia Li, Mahmoud Ghandi, Gabriel K. Griffin, Sunhee S. Kim, Justin Taylor, Lucia Cabal-Hierro, Christopher M. Kenyon, Christopher A.G. Booth, Vikas Madan, Sun Sook Chung, Katsuhiro Togami
Supplementary Figures S1-S8 with legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec467d08f4794ac5f85ded009f95a31
https://doi.org/10.1158/2159-8290.22541210.v1
https://doi.org/10.1158/2159-8290.22541210.v1
Autor:
Andrew A. Lane, H. Phillip Koeffler, Omar Abdel-Wahab, Francine Garnache-Ottou, Naveen Pemmaraju, Marina Konopleva, Henry Yang, Peter S. Hammerman, David M. Weinstock, Pier Paolo Piccaluga, Fabrice Jardin, Elizabeth A. Morgan, Abner Louissaint, Scott B. Lovitch, Silvia Buonamici, Michael Seiler, Sabeha Biichle, Fanny Angelot-Delettre, Yvonne Y. Li, Jia Li, Mahmoud Ghandi, Gabriel K. Griffin, Sunhee S. Kim, Justin Taylor, Lucia Cabal-Hierro, Christopher M. Kenyon, Christopher A.G. Booth, Vikas Madan, Sun Sook Chung, Katsuhiro Togami
Supplementary Tables 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4cf23850ead9d18cd22d06c66aecea
https://doi.org/10.1158/2159-8290.22541204
https://doi.org/10.1158/2159-8290.22541204
Autor:
Andrew A. Lane, H. Phillip Koeffler, Omar Abdel-Wahab, Francine Garnache-Ottou, Naveen Pemmaraju, Marina Konopleva, Henry Yang, Peter S. Hammerman, David M. Weinstock, Pier Paolo Piccaluga, Fabrice Jardin, Elizabeth A. Morgan, Abner Louissaint, Scott B. Lovitch, Silvia Buonamici, Michael Seiler, Sabeha Biichle, Fanny Angelot-Delettre, Yvonne Y. Li, Jia Li, Mahmoud Ghandi, Gabriel K. Griffin, Sunhee S. Kim, Justin Taylor, Lucia Cabal-Hierro, Christopher M. Kenyon, Christopher A.G. Booth, Vikas Madan, Sun Sook Chung, Katsuhiro Togami
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in men than in women, but the reasons for this sex bias are unknown. Here, studyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d7f9d5d3f428fa805864e0d5204040
https://doi.org/10.1158/2159-8290.c.6549572
https://doi.org/10.1158/2159-8290.c.6549572
Autor:
Andrew A. Lane, H. Phillip Koeffler, Omar Abdel-Wahab, Francine Garnache-Ottou, Naveen Pemmaraju, Marina Konopleva, Henry Yang, Peter S. Hammerman, David M. Weinstock, Pier Paolo Piccaluga, Fabrice Jardin, Elizabeth A. Morgan, Abner Louissaint, Scott B. Lovitch, Silvia Buonamici, Michael Seiler, Sabeha Biichle, Fanny Angelot-Delettre, Yvonne Y. Li, Jia Li, Mahmoud Ghandi, Gabriel K. Griffin, Sunhee S. Kim, Justin Taylor, Lucia Cabal-Hierro, Christopher M. Kenyon, Christopher A.G. Booth, Vikas Madan, Sun Sook Chung, Katsuhiro Togami
DNA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d61c9709474767dec1a2bb0d3c8eb0
https://doi.org/10.1158/2159-8290.22541207
https://doi.org/10.1158/2159-8290.22541207
Autor:
Andrew A. Lane, Anthony Letai, Naveen Pemmaraju, Marina Konopleva, Richard M. Stone, Nicole R. LeBoeuf, Matthew S. Davids, Jon C. Aster, Elizabeth A. Morgan, Ilene Galinsky, Leah J. Hogdal, Katsuhiro Togami, Lucia Cabal-Hierro, Gabriel K. Griffin, Tianyu Cai, Jason Stephansky, Joan Montero
Response of BPDCN and AML cells to navitoclax and A-1331852. (A) MTT assay results for the indicated cell lines after 72 hours of exposure to the indicated doses of navitoclax (combined BCL-2/BCL-XL inhibitor). (B) MTT assay results for the indicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e97576d3addcbb51384c4cb00f54c15
https://doi.org/10.1158/2159-8290.22531389.v1
https://doi.org/10.1158/2159-8290.22531389.v1
Autor:
Peter J. O'Dwyer, Lucia Cabal-Hierro
TNF and SN38 combination in HT29 cells induces both apoptosis and necrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8f93947c1f4883b735f59be49170cb
https://doi.org/10.1158/1541-7786.22511271.v1
https://doi.org/10.1158/1541-7786.22511271.v1
Autor:
Andrew A. Lane, Anthony Letai, Naveen Pemmaraju, Marina Konopleva, Richard M. Stone, Nicole R. LeBoeuf, Matthew S. Davids, Jon C. Aster, Elizabeth A. Morgan, Ilene Galinsky, Leah J. Hogdal, Katsuhiro Togami, Lucia Cabal-Hierro, Gabriel K. Griffin, Tianyu Cai, Jason Stephansky, Joan Montero
Pathological analysis of human BPDCN growing as a patient-derived xenograft (PDX) in mice. Splenic tissue is shown stained with H&E (at 40x and 100x magnification), and human BCL-2, CD45, CD4, CD56, and CD123 (all at 40x) from animals bearing a repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629b2195bd995bc6da7c18964377efc8
https://doi.org/10.1158/2159-8290.22531386.v1
https://doi.org/10.1158/2159-8290.22531386.v1
Autor:
Peter J. O'Dwyer, Lucia Cabal-Hierro
IC50 ratios comparing changes in sensitivity to different drugs by themselves or in combination with TNF (30 ng/ml). Values calculated by comparing IC50 Drug/ IC50 Drug + TNF both in normoxia and hypoxia conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e34f49cc108493539799a568feb296
https://doi.org/10.1158/1541-7786.22511265
https://doi.org/10.1158/1541-7786.22511265