Tim-3 Is Differentially Expressed during Cell Activation and Interacts with the LSP-1 Protein in Human Macrophages

Autor: Ranferi Ocaña-Guzman, Lucero A. Ramon-Luing, Luis A. Vazquez-Bolaños, Michelle Rodríguez-Alvarado, Fausi Bulhusen-Rodriguez, Alonso Torres-Hatem, Karen Gonzalez-Torres, Mariana Citlalli de Alba-Alvarado, Isabel Sada-Ovalle

Publikováno v: Journal of Immunology Research, Vol 2023 (2023)

T-cell Immunoglobulin and Mucin Domain 3 (TIM-3) is an immune checkpoint receptor known to regulate T-cell activation and has been targeted for immunotherapy in cancer and other diseases. However, its expression and function in other cell types, such

Externí odkaz: https://doaj.org/article/c67195899b694092a81fd7d27fbd5f5b

Anti-tuberculosis chemotherapy alters TNFR2 expression on CD4+ lymphocytes in both drug-sensitive and -resistant tuberculosis: however, only drug-resistant tuberculosis maintains a pro-inflammatory profile after a long time

Autor: Norma A. Téllez-Navarrete, Lucero A. Ramon-Luing, Marcela Muñoz-Torrico, Mario Preciado-García, Karen Medina-Quero, Rogelio Hernandez-Pando, Leslie Chavez-Galan

Publikováno v: Molecular Medicine, Vol 27, Iss 1, Pp 1-14 (2021)

Abstract Background Tuberculosis (TB) is an infectious disease. During TB, regulatory T cells (Treg) are related to poor prognosis. However, information about conventional and unconventional Treg (cTreg and uTreg, respectively) is limited. The tumour

Externí odkaz: https://doaj.org/article/17cd49126dcd46bf9f245f566589fff5

Diverse Cell Death Mechanisms Are Simultaneously Activated in Macrophages Infected by Virulent Mycobacterium tuberculosis

Autor: Lucero A. Ramon-Luing, Yessica Olvera, Julio Flores-Gonzalez, Yadira Palacios, Claudia Carranza, Yerany Aguilar-Duran, Marco Antonio Vargas, Neptali Gutierrez, Karen Medina-Quero, Leslie Chavez-Galan

Publikováno v: Pathogens, Vol 11, Iss 5, p 492 (2022)

Macrophages are necessary to eliminate pathogens. However, some pathogens have developed mechanisms to avoid the immune response. One of them is modulating the cell death mechanism to favor pathogen survival. In this study, we evaluated if virulent M

Externí odkaz: https://doaj.org/article/f0e1f54834114b3ebdf33c4f43d8ad96

Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity

Autor: José Alberto Choreño-Parra, José-Luis Carrillo-Alduenda, Karen Medina-Quero, Joaquín Zúñiga, Leslie Chavez-Galan, Ranferi Ocaña-Guzman, Iliana Herrera, Lucero A. Ramon-Luing, Norma A Téllez-Navarrete, Marlon De Ita

Publikováno v: Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains as a leading infectious cause of death worldwide. The increasing number of multidrug-resistant TB (MDR-TB) cases contributes to the poor control of the TB epidemic. Currently, lit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3462d9d0c3dfe497978060e428ce168
https://doi.org/10.1155/2021/6654220

Mycobacterium tuberculosis H37Rv Strain Increases the Frequency of CD3+TCR+ Macrophages and Affects Their Phenotype, but Not Their Migration Ability

Autor: Lucero A. Ramon-Luing, Claudia Carranza, Norma A. Téllez-Navarrete, Karen Medina-Quero, Yolanda Gonzalez, Martha Torres, Leslie Chavez-Galan

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 329
International Journal of Molecular Sciences, Vol 23, Iss 329, p 329 (2022)

In mycobacterial infections, the number of cells from two newly discovered subpopulations of CD3+ myeloid cells are increased at the infection site; one type expresses the T cell receptor (CD3+TCRαβ+) and the other does not (CD3+TCRαβ−). The ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc774746aaddac5e13e5363e1f78bf1
http://europepmc.org/articles/PMC8745617