Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Luce Boulanger"'
Autor:
Serge Nolet, Zaki El-Haffaf, Nelly Burnichon, Jessica Moramarco, André Lacroix, Pavel Hamet, Nadine Dumas, Luce Boulanger, Nada El Ghorayeb, Anne-Paule Gimenez Roqueplo, Isabelle Bourdeau
Publikováno v:
Clinical endocrinology. 86(3)
SummaryIntroduction Guidelines do not currently recommend routine systematic hormonal screening for pheochromocytoma (PHEO) in all/normotensive patients with neurofibromatosis type 1 (NF1), in contrast to other PHEO-predisposing genetic syndromes suc
Publikováno v:
Endocrinology. 140:2836-2842
In aging, alterations of pituitary GH-releasing hormone (GHRH) receptor (GHRH-R)-binding sites have been proposed as one of the initiating factors contributing to the loss of somatotroph responsiveness to GHRH. Changes in the characteristics and/or c
Publikováno v:
Neuroendocrinology. 70:117-127
A site-directed polyclonal antipeptide antibody was generated in rabbits against segment 392–404 of the rat pituitary growth hormone-releasing hormone receptor (GHRH-R), using a multiple antigenic peptide system strategy of immunization. This C-ter
Autor:
E Pintos, Luce Boulanger, Tomás García-Caballero, Rosalía Gallego, Gérard Morel, Pierrette Gaudreau
Publikováno v:
Neuroendocrinology. 70:128-136
Specific binding of growth hormone-releasing hormone (GHRH) to its plasma membrane receptor represents the first step of cellular signals leading to exocytotic GH secretion in the anterior pituitary. The GHRH receptor (GHRH-R) has been cloned and bel
Publikováno v:
Brain Research. 673:39-46
We have investigated the effect of 5′-guanylylimidodiphosphate (Gpp(NH)p) and two disulfide bond reducing agents, reduced glutathione (GSH) and dithiothreitol (DTT), on the modulation of [ 125 I-Tyr 10 ]hGRF(1–44)NH 2 binding to GRF receptor bind
Publikováno v:
Brain Research. 616:39-47
The identification of peptide bonds vulnerable to tissue peptidases is a valuable approach to design peptide agonists which exhibit a longer duration of action than the native molecules. Therefore, the kinetic of disappearance of rat growth hormone-r
Publikováno v:
Journal of Medicinal Chemistry. 35:1864-1869
Previous research on growth hormone-releasing factor analogues has used pituitary cell culture assay systems to evaluate in vitro their biological activity. However, binding assay systems in which receptor affinity and peptide stability can be assess
Publikováno v:
Peptides. 23(1)
Receptor binding analysis was performed in the renal medulla from 2-month-old rats, an extrapituitary tissue containing the highest level of GHRH receptor mRNA. At 4 °C, in the presence of a cocktail of protease inhibitors, binding of [ 125 I -Tyr 1
Publikováno v:
Clinical Biochemistry. 47:1154
Publikováno v:
Neuroendocrinology. 68(1)
In mammals, middle age and late adulthood is characterized by a decrease of growth hormone (GH) secretion and insulin-like growth factor 1 (IGF-1) serum levels, contributing to tissue and organ atrophy. This condition is related, at least in part, to