Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Lucas de Almeida Machado"'
1
Akademický článek
Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony
Autor: Anabel Zabala-Peñafiel, Geovane Dias-Lopes, Léa Cysne-Finkelstein, Fátima Conceição-Silva, Luciana de Freitas Campos Miranda, Aline Fagundes, Armando de Oliveira Schubach, Maria Inês Fernandes Pimentel, Franklin Souza-Silva, Lucas de Almeida Machado, Carlos Roberto Alves
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes. In this study, 12 Leishmania (Viannia) bra
Externí odkaz: https://doaj.org/article/c189acbd39044fa790974bc4c3479a94
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2
Akademický článek
M. bovis BCG Moreau N-Terminal Loss Leads to a Less Stable Dodecin With Lower Flavin Binding Capacity
Autor: Marcos Gustavo Araujo Schwarz, Bianca Gallart Cinelli Luzes, Paloma Rezende Correa, Antônio José da Silva-Gonçalves, Lucas de Almeida Machado, Ana Carolina Ramos Guimarães, Leila Mendonça-Lima
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Tuberculosis still remains a concerning health problem worldwide. Its etiologic agent, Mycobacterium tuberculosis, continues to be the focus of research to unravel new prophylactic and therapeutic strategies against this disease. The only vaccine in
Externí odkaz: https://doaj.org/article/050ed347d4f443bea0260822aa8f4b9e
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3
Akademický článek
Evidence for Disruption of Mg2+ Pair as a Resistance Mechanism Against HIV-1 Integrase Strand Transfer Inhibitors
Autor: Lucas de Almeida Machado, Ana Carolina Ramos Guimarães
Publikováno v: Frontiers in Molecular Biosciences, Vol 7 (2020)
HIV-1 integrase is the enzyme responsible for integrating the viral DNA into the host genome and is one of the main targets for antiretroviral therapy; however, there are documented cases of resistance against all the currently used integrase strand
Externí odkaz: https://doaj.org/article/2087aa32bfca4e50939fe9baca1471ae
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4
Akademický článek
Raltegravir-Induced Adaptations of the HIV-1 Integrase: Analysis of Structure, Variability, and Mutation Co-occurrence
Autor: Lucas de Almeida Machado, Marcelo Ferreira da Costa Gomes, Ana Carolina Ramos Guimarães
Publikováno v: Frontiers in Microbiology, Vol 10 (2019)
The human immunodeficiency virus type 1 (HIV-1) has several proteins of therapeutic importance, many of which are currently used as drug targets in antiretroviral therapy. Among these proteins is the integrase, which is responsible for the integratio
Externí odkaz: https://doaj.org/article/c494d827c66740c49d2889215958fbdd
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5
Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony
Autor: Lucas de Almeida Machado, Anabel Zabala-Peñafiel, Fátima Conceição-Silva, Maria Inês Fernandes Pimentel, Franklin Souza-Silva, Carlos Roberto Alves, Aline Fagundes, Armando de Oliveira Schubach, Luciana de Freitas Campos Miranda, Geovane Dias-Lopes, Léa Cysne-Finkelstein
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Background: Glucantime® (SbV) is considered the first-line treatment against American Tegumentary Leishmaniasis in South America, though increased parasite resistance towards it have been reported and hampered its effectiveness. In this context, sub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac213208e54e8ecc3ede0c2f3a820e6d
https://doi.org/10.1038/s41598-021-93665-z
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6
M. bovis BCG Moreau N-Terminal Loss Leads to a Less Stable Dodecin With Lower Flavin Binding Capacity
Autor: Lucas de Almeida Machado, Ana Carolina Ramos Guimarães, Leila Mendonça-Lima, Paloma Rezende Correa, Antônio José da Silva-Gonçalves, Bianca Gallart Cinelli Luzes, Marcos Gustavo Araujo Schwarz
Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Tuberculosis still remains a concerning health problem worldwide. Its etiologic agent, Mycobacterium tuberculosis, continues to be the focus of research to unravel new prophylactic and therapeutic strategies against this disease. The only vaccine in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f3f913671965bb9a12e2b582a23664
https://doi.org/10.3389/fcimb.2021.658888
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7
Cross-reactivity and immunotherapeutic potential of BamA recombinant protein from Acinetobacter baumannii
Autor: Anna Erika Vieira de Araujo, José Procópio Moreno Senna, Ana Paula D'Alincourt Carvalho-Assef, Alex Chapeaurouge, Lucas de Almeida Machado, Luis Caetano Martha Antunes, Flávio Alves Lara, Haroldo Cid da Silva Junior, Luis Vidal Conde, Heidi Pauer, Cristiane C. P. Hardoim
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:30:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01 Acinetobacter baumannii is an important nosocomial pathogen. BamA is a protein that belongs to a complex responsible for organizing the prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d39ff6206027fdf0889dd132b96ca35
https://doi.org/10.1016/j.micinf.2021.104801
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