Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lucas V. B. Hoelz"'
Autor:
Gianna Giacoletti, Tatum Price, Lucas V. B. Hoelz, Abdulwhab Shremo Msdi, Samantha Cossin, Katerina Vazquez-Falto, Tácio V. Amorim Fernandes, Vinícius Santos de Pontes, Hongbing Wang, Nubia Boechat, Adwoa Nornoo, Tarsis F. Brust
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Among the ten different adenylyl cyclase isoforms, studies with knockout animals indicate that inhibition of AC1 can relieve pain and reduce behaviors linked to opioid dependence. We previously identified ST034307 as a selective inhibitor of AC1. The
Externí odkaz:
https://doaj.org/article/76435072e50042cf8705511fe77f905f
Autor:
Daniel T. G. Gonzaga, Felipe H. Oliveira, N. L. von Ranke, G. Q. Pinho, Juliana P. Salles, Murilo L. Bello, Carlos R. Rodrigues, Helena C. Castro, Hellen V. C. M. de Souza, Caroline R. C. Reis, Rennan P. P. Leme, João C. M. Mafra, Luiz C. S. Pinheiro, Lucas V. B. Hoelz, Nubia Boechat, Robson X. Faria
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay),
Externí odkaz:
https://doaj.org/article/9ab312f8957145ae9c80d75e8662765a
Autor:
Lucas V. B. Hoelz
Publikováno v:
Australian Journal of Chemistry. 63:1307
This paper provides a description of tribromoisocyanuric acid (TBCA), a new reagent used as a source of electrophilic bromine (Br+) in organic synthesis, including in Green Chemistry procedures. Its applications embrace the bromination of alkenes, β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc35dfe9eaaaf83ed35566dd2cc152d
https://doi.org/10.1071/ch10150
https://doi.org/10.1071/ch10150
Autor:
Felipe Gazos-Lopes, Mauricio M Oliveira, Lucas V B Hoelz, Danielle P Vieira, Alexandre F Marques, Ernesto S Nakayasu, Marta T Gomes, Nasim G Salloum, Pedro G Pascutti, Thaïs Souto-Padrón, Robson Q Monteiro, Angela H Lopes, Igor C Almeida
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3077 (2014)
Trypanosoma cruzi is the causative agent of the life-threatening Chagas disease, in which increased platelet aggregation related to myocarditis is observed. Platelet-activating factor (PAF) is a potent intercellular lipid mediator and second messenge
Externí odkaz:
https://doaj.org/article/8162a50a9a61444f93aab6e03d3cba54