The Genetic Basis of Probable REM Sleep Behavior Disorder in Parkinson’s Disease

Autor: Santiago Perez-Lloret, Guenson Chevalier, Sofia Bordet, Hanny Barbar, Francisco Capani, Lucas Udovin, Matilde Otero-Losada

Publikováno v: Brain Sciences, Vol 13, Iss 8, p 1146 (2023)

Patients with Parkinson’s Disease (PD) experience REM sleep behavior disorder (RBD) more frequently than healthy controls. RBD is associated with torpid disease evolution. To test the hypothesis that differential genetic signatures might contribute

Externí odkaz: https://doaj.org/article/d5e9adde47ab48939474505b0660d97b

The Renin–Angiotensin System Modulates Dopaminergic Neurotransmission: A New Player on the Scene

Autor: Tamara Kobiec, Matilde Otero-Losada, Guenson Chevalier, Lucas Udovin, Sofía Bordet, Camila Menéndez-Maissonave, Francisco Capani, Santiago Pérez-Lloret

Publikováno v: Frontiers in Synaptic Neuroscience, Vol 13 (2021)

Parkinson’s disease (PD) is an extrapyramidal disorder characterized by neuronal degeneration in several regions of the peripheral and central nervous systems. It is the second most frequent neurodegenerative disease after Alzheimer’s. It has bec

Externí odkaz: https://doaj.org/article/c462b0c9d3dc44b9af4e935012213560

Interleukin-1 Links Autoimmune and Autoinflammatory Pathophysiology in Mixed-Pattern Psoriasis

Autor: Rodolfo Kölliker Frers, Matilde Otero-Losada, Tamara Kobiec, María Inés Herrera, Lucas Udovin, Carlos F. Kusnier, Francisco Capani

Publikováno v: Mediators of Inflammation, Vol 2021 (2021)

Autoinflammatory and autoimmune diseases are characterized by an oversensitive immune system with loss of the physiological endogenous regulation, involving multifactorial self-reactive pathological mechanisms of mono- or polygenic nature. Failure in

Externí odkaz: https://doaj.org/article/a1bc3124daa54dce994ffb77b020ec52

Role of Astrocytic Dysfunction in the Pathogenesis of Parkinson’s Disease Animal Models from a Molecular Signaling Perspective

Autor: Lucas Udovin, Cecilia Quarracino, María I. Herrera, Francisco Capani, Matilde Otero-Losada, Santiago Perez-Lloret

Publikováno v: Neural Plasticity, Vol 2020 (2020)

Despite the fact that astrocytes are the most abundant glial cells, critical for brain function, few studies have dealt with their possible role in neurodegenerative diseases like Parkinson’s disease (PD). This article explores relevant evidence on

Externí odkaz: https://doaj.org/article/d372a0f3d28a4d9f86cf33fda100b4cc

In Vivo Studies of Protein Misfolding and Neurodegeneration Induced by Metabolic Syndrome Relative to Chronic Cerebral Hypoperfusion: A Critical Review

Autor: Matilde Otero-Losada, Nicolás Toro-Urrego, Lucas Udovin, María Inés Herrera, Francisco Capani, Juan Pablo Luaces

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neuroprotection-New Approaches and Prospects

Metabolic syndrome (MetS) leads to microvascular dysfunction and chronic cerebral hypoperfusion (CCH) in an insidious way. Clinical evidence and several rodent models have contributed to determining the neurodegenerative effect of a sustained decreas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fa1fffb7015e1fb7c7520770f698f7
https://doi.org/10.5772/intechopen.92603