Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lucas SCC"'
Autor:
Palisse A; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Cheung T; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Blokhuis A; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Cogswell T; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Martins BS; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Riemens R; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Schellekens R; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Battocchio G; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Jansen C; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Cottee MA; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ornell K; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Sacchetto C; Bioscience, Oncology, R&D, Acerta B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Leon L; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., van Hoek-Emmelot M; Bioscience, Oncology, R&D, Acerta B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Bostock M; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Brauer BL; Chemical Biology and Proteomics, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Beaumont K; DMPK, AstraZeneca, Cambridge CB2 0AA, U.K., Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ahmed S; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Blackwell JH; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83, Sweden., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Gramatikov IMT; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Hargreaves D; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., van Hoeven V; Bioscience, Oncology, R&D, Acerta B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands., Kantae V; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Kupcova L; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Seneviratne U; Chemical Biology and Proteomics, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Su N; Mechanistic Biology and Profiling, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Vales J; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Wang H; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., White MJ; Bioscience, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Kinzel O; Medicinal Chemistry, Oncology, R&D, Acerta Pharma B.V., A member of the AstraZeneca Group, Oss 5349 AB, The Netherlands.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Dec 06. Date of Electronic Publication: 2024 Dec 06.
Autor:
Ashraf SN; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK., Blackwell JH; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK., Holdgate GA; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK., Lucas SCC; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK., Solovyeva A; Hit Discovery, Discovery Science, AstraZeneca R&D, Gothenburg SE-431 83, Sweden., Storer RI; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK. Electronic address: ian.storer@astrazeneca.com., Whitehurst BC; Hit Discovery, Discovery Science, AstraZeneca R&D, Cambridge CB2 0AA, UK.
Publikováno v:
Drug discovery today [Drug Discov Today] 2024 Oct; Vol. 29 (10), pp. 104143. Date of Electronic Publication: 2024 Aug 22.
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Blackwell JH; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83, Sweden., Hargreaves D; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ahmed S; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Beaumont K; DMPK, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Cheung T; Oncology Bioscience, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Demanze S; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Guerot C; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Haider A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Kantae V; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Kauffman GW; Medicinal Chemistry, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Kinzel O; Medicinal Chemistry, Oncology R&D, Acerta B.V., a Member of the AstraZeneca Group, Oss 5349, The Netherlands., Kupcova L; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Lainchbury MD; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Lamb ML; Medicinal Chemistry, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Leon L; Oncology Bioscience, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Palisse A; Medicinal Chemistry, Oncology R&D, Acerta B.V., a Member of the AstraZeneca Group, Oss 5349, The Netherlands., Sacchetto C; Bioscience, Oncology R&D, Acerta B.V., a Member of the AstraZeneca Group, Oss 5349, The Netherlands., Storer RI; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Su N; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Thomson C; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Vales J; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Chen Y; Pharmaron Beijing Co., Ltd., Beijing 100176, P. R. China., Hu X; Pharmaron Beijing Co., Ltd., Beijing 100176, P. R. China.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16455-16479. Date of Electronic Publication: 2024 Sep 18.
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Blackwell JH; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Bonomo S; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Brierley A; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Cassar DJ; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Freeman J; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolic Disorders (CVRM), Biopharmaceuticals R&D, AstraZeneca, Gothenburg, SE-43183, Sweden., Hadfield TE; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Morrill LA; Medicinal Chemistry, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Riemens R; Medicinal Chemistry, Oncology R&D, Acerta B. V., a Part of the AstraZeneca Group, Oss 5349, The Netherlands., Sarda S; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Schiesser S; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology (R&I), Biopharmaceuticals R&D, AstraZeneca, Gothenburg, SE-43183, Sweden., Wiktelius D; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca, Gothenburg, SE-43183, Sweden., Ahmed S; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg, SE-43183, Sweden., De Fusco C; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Guerot C; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Hargreaves D; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Hewitt S; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Lamb ML; Medicinal Chemistry, Oncology R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Su N; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Whatling R; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Wheeler M; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Kettle JG; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Jul 11; Vol. 67 (13), pp. 11209-11225. Date of Electronic Publication: 2024 Jun 25.
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Blackwell JH; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83, Sweden., Hargreaves D; Mechanistic and Structural Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Ahmed S; Discovery Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Guerot C; Medicinal Chemistry, Oncology, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Kinzel O; Medicinal Chemistry, Oncology, R&D, Acerta B.V., a member of the AstraZeneca Group, Oss 5349, The Netherlands., Lamb ML; Medicinal Chemistry, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Selmi N; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83, Sweden., Stubbs CJ; Mechanistic and Structural Biology, Discovery Sciences, R&DAstraZeneca, Cambridge CB2 0AA, U.K., Su N; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Su Q; Medicinal Chemistry, Oncology, R&D, AstraZeneca, Waltham, Massachusetts 02451, United States., Luo H; Pharmaron Beijing Co., Ltd., Beijing 100176, P. R. China., Xiong T; Pharmaron Beijing Co., Ltd., Beijing 100176, P. R. China., Zuo X; Pharmaron Beijing Co., Ltd., Beijing 100176, P. R. China., Bazzaz S; X-Chem Inc., Waltham, Massachusetts 02453, United States., Bienstock C; X-Chem Inc., Waltham, Massachusetts 02453, United States., Centrella PA; X-Chem Inc., Waltham, Massachusetts 02453, United States., Denton KE; X-Chem Inc., Waltham, Massachusetts 02453, United States., Gikunju D; X-Chem Inc., Waltham, Massachusetts 02453, United States., Guié MA; X-Chem Inc., Waltham, Massachusetts 02453, United States., Guilinger JP; X-Chem Inc., Waltham, Massachusetts 02453, United States., Hupp C; X-Chem Inc., Waltham, Massachusetts 02453, United States., Keefe AD; X-Chem Inc., Waltham, Massachusetts 02453, United States., Satoh T; X-Chem Inc., Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem Inc., Waltham, Massachusetts 02453, United States., Rivers EL; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 May 20; Vol. 15 (6), pp. 791-797. Date of Electronic Publication: 2024 May 20 (Print Publication: 2024).
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ahmed A; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ashraf SN; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Argyrou A; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Bauer MR; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., De Donatis GM; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Demanze S; Oncology Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Eisele F; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83,Sweden., Fusani L; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Hock A; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Kadamur G; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Li S; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, People's Republic of China., Macmillan-Jones A; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Michaelides IN; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Phillips C; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Rehnström M; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg SE-431 83, Sweden., Richter M; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Rodrigo-Brenni MC; Safety Innovation and PROTAC Safety, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Shilliday F; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Wang P; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, People's Republic of China., Storer RI; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Apr 11; Vol. 67 (7), pp. 5538-5566. Date of Electronic Publication: 2024 Mar 21.
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, AstraZeneca R&D, Cambridge, UK. Electronic address: simon.lucas1@astrazeneca.com., Blackwell JH; Hit Discovery, Discovery Sciences, AstraZeneca R&D, Cambridge, UK., Hewitt SH; Mechanistic and Structural Biology, Discovery Sciences, AstraZeneca R&D, Cambridge, UK., Semple H; Hit Discovery, Discovery Sciences, AstraZeneca R&D, Cambridge, UK., Whitehurst BC; Hit Discovery, Discovery Sciences, AstraZeneca R&D, Cambridge, UK., Xu H; Mechanistic and structural Biology, Discovery Sciences, AstraZeneca R&D, Waltham, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2024 Apr; Vol. 29 (3), pp. 100142. Date of Electronic Publication: 2024 Jan 24.
Autor:
Jones SP; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk., Firth JD; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk., Wheldon MC; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk., Atobe M; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk.; Asahi Kasei Pharma Corporation 632-1 Mifuku, Izunokuni Shizuoka 410-2321 Japan., Hubbard RE; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk.; Vernalis (R&D) Ltd. Granta Park, Abington Cambridge CB21 6GB UK., Blakemore DC; Medicine Design, Pfizer Inc. 445 Eastern Point Road Groton CT 06340 USA., De Fusco C; Bayer AG, Research and Development, Pharmaceuticals, Synthetic Modalities 13353 Berlin Germany., Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge CB4 0WG UK., Roughley SD; Vernalis (R&D) Ltd. Granta Park, Abington Cambridge CB21 6GB UK., Vidler LR; Amphista Therapeutics The Cori Building, Granta Park, Great Abington Cambridge CB21 6GQ UK., Whatton MA; Evotec (UK) Ltd Dorothy Crowfoot Hodgkin Campus, 114 Innovation Drive, Milton Park, Abingdon Oxon OX14 4RZ UK., Woolford AJ; Astex Pharmaceuticals 436 Cambridge Science Park, Milton Road Cambridge CB4 0QA UK., Wrigley GL; Medicinal Chemistry, Oncology R&D, AstraZeneca Cambridge UK., O'Brien P; Department of Chemistry, University of York Heslington York YO10 5DD UK peter.obrien@york.ac.uk.
Publikováno v:
RSC medicinal chemistry [RSC Med Chem] 2022 Oct 11; Vol. 13 (12), pp. 1614-1620. Date of Electronic Publication: 2022 Oct 11 (Print Publication: 2022).
Autor:
Lucas SCC; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Börjesson U; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Bostock MJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Cuff J; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Edfeldt F; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Embrey KJ; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Eriksson PO; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Gohlke A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Gunnarson A; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Gothenburg Sweden., Lainchbury M; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com., Milbradt AG; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Moore R; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Rawlins PB; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Sinclair I; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca Alderley Park UK., Stubbs C; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca Cambridge UK., Storer RI; Hit Discovery, Discovery Sciences, R&D, AstraZeneca Cambridge UK simon.lucas1@astrazeneca.com.
Publikováno v:
RSC medicinal chemistry [RSC Med Chem] 2022 Jul 04; Vol. 13 (9), pp. 1052-1057. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).
Autor:
Lucas SCC, Atkinson SJ, Chung CW, Davis R, Gordon L, Grandi P; IVIVT Cellzome, Platform Technology and Science, GlaxoSmithKline, Meyerhofstrasse 1, 69117 Heidelberg, Germany., Gray JJR, Grimes T, Phillipou A, Preston AG, Prinjha RK, Rioja I, Taylor S, Tomkinson NCO; WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 259 Cathedral Street, Glasgow G1 1XL, U.K., Wall I, Watson RJ, Woolven J, Demont EH
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Aug 12; Vol. 64 (15), pp. 10711-10741. Date of Electronic Publication: 2021 Jul 14.