Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lucas R Sass"'
Autor:
Mohammadreza Khani, Braden J Lawrence, Lucas R Sass, Christina P Gibbs, Joshua J Pluid, John N Oshinski, Gregory R Stewart, Jillynne R Zeller, Bryn A Martin
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212239 (2019)
Recent advancements have been made toward understanding the diagnostic and therapeutic potential of cerebrospinal fluid (CSF) and related hydrodynamics. Increased understanding of CSF dynamics may lead to improved detection of central nervous system
Externí odkaz:
https://doaj.org/article/13ae97fe63ba48a69fe14fd69f632992
Autor:
Mohammadreza Khani, Goutham Kumar Reddy Burla, Lucas R. Sass, Ostin N. Arters, Tao Xing, Haiming Wu, Bryn A. Martin
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Intrathecal drug delivery has a significant role in pain management and central nervous system (CNS) disease therapeutics. A fluid-physics based tool to assist clinicians in choosing specific drug doses to the spine or brain may h
Externí odkaz:
https://doaj.org/article/1a39812d5482420ebed02d1d88cd02e2
Autor:
Mohammadreza Khani, Lucas R. Sass, M. Keith Sharp, Aaron R. McCabe, Laura M. Zitella Verbick, Shivanand P. Lad, Bryn A. Martin
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background Blood removal from cerebrospinal fluid (CSF) in post-subarachnoid hemorrhage patients may reduce the risk of related secondary brain injury. We formulated a computational fluid dynamics (CFD) model to investigate the impact of a d
Externí odkaz:
https://doaj.org/article/9818cf6ab2e142139f43ce552561e0ec
Autor:
Lucas R. Sass, Mohammadreza Khani, Gabryel Connely Natividad, R. Shane Tubbs, Olivier Baledent, Bryn A. Martin
Publikováno v:
Fluids and Barriers of the CNS, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background The spinal subarachnoid space (SSS) has a complex 3D fluid-filled geometry with multiple levels of anatomic complexity, the most salient features being the spinal cord and dorsal and ventral nerve rootlets. An accurate anthropomor
Externí odkaz:
https://doaj.org/article/4c36688b48be458b9e04eee1f9dfe6df
Autor:
Ostin N. Arters, Tao Xing, Lucas R. Sass, Bryn A. Martin, Goutham Kumar Reddy Burla, Mohammadreza Khani, Haiming Wu
Publikováno v:
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-16 (2022)
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-16 (2022)
Background Intrathecal drug delivery has a significant role in pain management and central nervous system (CNS) disease therapeutics. A fluid-physics based tool to assist clinicians in choosing specific drug doses to the spine or brain may help impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569190ef5bef1ee0ba921568ccfa3d72
http://europepmc.org/articles/PMC8796513
http://europepmc.org/articles/PMC8796513
Autor:
Laura Zitella Verbick, Shivanand P. Lad, M. Keith Sharp, Mohammadreza Khani, Aaron McCabe, Bryn A. Martin, Lucas R. Sass
Publikováno v:
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-17 (2020)
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-17 (2020)
Background Blood removal from cerebrospinal fluid (CSF) in post-subarachnoid hemorrhage patients may reduce the risk of related secondary brain injury. We formulated a computational fluid dynamics (CFD) model to investigate the impact of a dual-lumen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dce35affed47197f0271b988c00ea41
https://doi.org/10.1186/s12987-020-00185-5
https://doi.org/10.1186/s12987-020-00185-5
Autor:
Jason Aldred, Bryn A. Martin, Brian Petersen, Tavara Freeman, Kyle McCain, Douglas L. Weeks, Marianne Schmid Daners, Jacob Romm, Dena Wingett, Mohammadreza Khani, Gregory T. Carter, Lucas R. Sass
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-14 (2020)
Fluids and Barriers of the CNS, 17 (1)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, 17 (1)
Fluids and Barriers of the CNS
Background:Developing novel therapeutic agents to treat amyotrophic lateral sclerosis (ALS) has been difficult due to multifactorial pathophysiologic processes at work. Intrathecal drug administration shows promise due to close proximity of cerebrosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff1aed6ff2faeab20f5469a1192ebad
Autor:
Mohammadreza Khani, Joshua Pluid, Lucas R. Sass, Gregory R. Stewart, Jillynne R. Zeller, Braden J. Lawrence, John N. Oshinski, Christina P. Gibbs, Bryn A. Martin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212239 (2019)
PLoS ONE, Vol 14, Iss 2, p e0212239 (2019)
Recent advancements have been made toward understanding the diagnostic and therapeutic potential of cerebrospinal fluid (CSF) and related hydrodynamics. Increased understanding of CSF dynamics may lead to improved detection of central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f7f47ea1473d7a6237ac3d1a570214
https://pubmed.ncbi.nlm.nih.gov/30811449
https://pubmed.ncbi.nlm.nih.gov/30811449
Autor:
M. Keith Sharp, Olivier Balédent, Tao Xing, Bryn A. Martin, Lucas R. Sass, Mohammadreza Khani
Publikováno v:
Journal of Biomechanical Engineering. 140
Cerebrospinal fluid (CSF) dynamics are thought to play a vital role in central nervous system (CNS) physiology. The objective of this study was to investigate the impact of spinal cord (SC) nerve roots (NR) on CSF dynamics. A subject-specific computa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d912b5f4c4f619249b0d130dbdd8195
https://doi.org/10.1115/1.4040401
https://doi.org/10.1115/1.4040401
Autor:
Jan-Robert Kroger, Lucas R. Sass, Bryn A. Martin, Francis Loth, R. Shane Tubbs, Soroush Heidari Pahlavian, Morteza Vatani, Jae-Won Choi, Suraj Thyagaraj, Daniel Giese, Alexander C. Bunck
Publikováno v:
IEEE transactions on bio-medical engineering. 65(7)
Goal: Develop and test an MRI-compatible hydrodynamic simulator of cerebrospinal fluid (CSF) motion in the cervical spinal subarachnoid space. Four anatomically realistic subject-specific models were created based on a 22-year-old healthy volunteer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b652535891ad91a2fe58864b40f65ec8
https://pubmed.ncbi.nlm.nih.gov/28961100
https://pubmed.ncbi.nlm.nih.gov/28961100