Copper-Catalyzed Regio- and Stereoselective Hydrothiolation of Allenamides, Enamides, and Ynamides

Autor: Lucas Pagès, Maxime Bouquin, Florian Jaroschik, Florian Monnier, Marc Taillefer

Publikováno v: The Journal of Organic Chemistry. 88:1168-1176

We report a simple protocol for the copper-catalyzed hydrothiolation of N-unsaturated precursors, i.e., allenamides, enamides, and ynamides, under mild conditions. This method proceeds with a low loading of a commercially available Cu(CH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc597366dec635bfc0cbde160681f6e
https://doi.org/10.1021/acs.joc.2c02716

Hydroarylation of N ‐Allenyl Derivatives Catalyzed by Copper

Autor: Florian Monnier, Lucas Pagès, Marc Taillefer, Racha Abed Ali Abdine

Publikováno v: European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2020, 2020 (48), pp.7466-7469. ⟨10.1002/ejoc.202001333⟩

A simple copper catalytic system was used to perform the addition of (hetero)aryl nucleophiles to N-allenyl derivatives. This intermolecular C-C bond formation occurs with both complete regio- and stereoselectivity to afford the linear (E) allylic pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25d7ab6f220e2f6ba2751f1eb2c74ac
https://hal.archives-ouvertes.fr/hal-03450694