Diagnostic performance of Typhidot RDT in diagnosis of typhoid fever and antibiotic resistance characterisation in a cross-sectional study in Southern Ghana

Autor: Emmanuel Kweku Sam, Johnson Alagbo, Avis Asamoah, Felix Ansah, Kwesi Zandoh Tandoh, Lucas N. Amenga-Etego, Samuel Duodu

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)

Abstract Background Typhoid fever remains a significant public health problem contributing to significant misapplication of antibiotics in Ghana. However, there is little data on the accuracy of the commonly used serology based rapid diagnostic Typhi

Externí odkaz: https://doaj.org/article/c8b7de9993a34724ba61ddc763c8fc7f

Plasmodium malariae structure and genetic diversity in sub-Saharan Africa determined from microsatellite variants and linked SNPs in orthologues of antimalarial resistance genes

Autor: Eniyou C. Oriero, Martha A. Demba, Mouhamadou F. Diop, Deus S. Ishengoma, Lucas N. Amenga-Etego, Anita Ghansah, Tobias Apinjoh, Soulama Issiaka, Abdoulaye Djimde, Umberto D’Alessandro, Martin Meremikwu, Alfred Amambua-Ngwa

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract Plasmodium malariae, a neglected human malaria parasite, contributes up to 10% of malaria infections in sub-Saharan Africa (sSA). Though P. malariae infection is considered clinically benign, it presents mostly as coinfections with the domin

Externí odkaz: https://doaj.org/article/3706ced9d4434a18a440b3a188952187

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium falciparum in northern Ghana

Autor: Lucas N. Amenga-Etego, Victor Asoala, Godfred Agongo, Christopher Jacob, Sonia Goncalves, Gordon A. Awandare, Kirk A. Rockett, Dominic Kwiatkowski

Publikováno v: Malaria Journal, Vol 20, Iss 1, Pp 1-11 (2021)

Abstract Background Anti-malarial drug resistance remains a key concern for the global fight against malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive treatment of malaria in pregnancy and combined with amodiaquine

Externí odkaz: https://doaj.org/article/518f169edd4f48f9a3b4d7a23472e5cd

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

Autor: Geraldine M Clarke, Kirk Rockett, Katja Kivinen, Christina Hubbart, Anna E Jeffreys, Kate Rowlands, Muminatou Jallow, David J Conway, Kalifa A Bojang, Margaret Pinder, Stanley Usen, Fatoumatta Sisay-Joof, Giorgio Sirugo, Ousmane Toure, Mahamadou A Thera, Salimata Konate, Sibiry Sissoko, Amadou Niangaly, Belco Poudiougou, Valentina D Mangano, Edith C Bougouma, Sodiomon B Sirima, David Modiano, Lucas N Amenga-Etego, Anita Ghansah, Kwadwo A Koram, Michael D Wilson, Anthony Enimil, Jennifer Evans, Olukemi K Amodu, Subulade Olaniyan, Tobias Apinjoh, Regina Mugri, Andre Ndi, Carolyne M Ndila, Sophie Uyoga, Alexander Macharia, Norbert Peshu, Thomas N Williams, Alphaxard Manjurano, Nuno Sepúlveda, Taane G Clark, Eleanor Riley, Chris Drakeley, Hugh Reyburn, Vysaul Nyirongo, David Kachala, Malcolm Molyneux, Sarah J Dunstan, Nguyen Hoan Phu, Nguyen Ngoc Quyen, Cao Quang Thai, Tran Tinh Hien, Laurens Manning, Moses Laman, Peter Siba, Harin Karunajeewa, Steve Allen, Angela Allen, Timothy ME Davis, Pascal Michon, Ivo Mueller, Síle F Molloy, Susana Campino, Angeliki Kerasidou, Victoria J Cornelius, Lee Hart, Shivang S Shah, Gavin Band, Chris CA Spencer, Tsiri Agbenyega, Eric Achidi, Ogobara K Doumbo, Jeremy Farrar, Kevin Marsh, Terrie Taylor, Dominic P Kwiatkowski, MalariaGEN Consortium

Publikováno v: eLife, Vol 6 (2017)

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection against Plasmodium falciparum malaria, but the precise nature of the protective effect has proved difficult to define as G6PD deficiency has multiple allelic variant

Externí odkaz: https://doaj.org/article/f05449c1a20b4490b6413ada919611ca

Genetic diversity of SARS-CoV-2 infections in Ghana from 2020-2021

Autor: Collins M. Morang’a, Joyce M. Ngoi, Jones Gyamfi, Dominic S. Y. Amuzu, Benjamin D. Nuertey, Philip M. Soglo, Vincent Appiah, Ivy A. Asante, Paul Owusu-Oduro, Samuel Armoo, Dennis Adu-Gyasi, Nicholas Amoako, Joseph Oliver-Commey, Michael Owusu, Augustina Sylverken, Edward D. Fenteng, Violette V. M’cormack, Frederick Tei-Maya, Evelyn B. Quansah, Reuben Ayivor-Djanie, Enock K. Amoako, Isaac T. Ogbe, Bright K. Yemi, Israel Osei-Wusu, Deborah N. A. Mettle, Samirah Saiid, Kesego Tapela, Francis Dzabeng, Vanessa Magnussen, Jerry Quaye, Precious C. Opurum, Rosina A. Carr, Patrick T. Ababio, Abdul-Karim Abass, Samuel K. Akoriyea, Emmanuella Amoako, Frederick Kumi-Ansah, Oliver D. Boakye, Dam K. Mibut, Theophilus Odoom, Lawrence Ofori-Boadu, Emmanuel Allegye-Cudjoe, Sylvester Dassah, Victor Asoala, Kwaku P. Asante, Richard O. Phillips, Mike Y. Osei-Atweneboana, John O. Gyapong, Patrick Kuma-Aboagye, William K. Ampofo, Kwabena O. Duedu, Nicaise T. Ndam, Yaw Bediako, Peter K. Quashie, Lucas N. Amenga-Etego, Gordon A. Awandare

Publikováno v: Nature communications. 13(1)

The COVID-19 pandemic is one of the fastest evolving pandemics in recent history. As such, the SARS-CoV-2 viral evolution needs to be continuously tracked. This study sequenced 1123 SARS-CoV-2 genomes from patient isolates (121 from arriving travelle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176feaac8e7b5e2cd24717a54aeeb9d1
https://pubmed.ncbi.nlm.nih.gov/35523782