Predicting responders to prone positioning in mechanically ventilated patients with COVID-19 using machine learning

Autor: Tariq A. Dam, Luca F. Roggeveen, Fuda van Diggelen, Lucas M. Fleuren, Ameet R. Jagesar, Martijn Otten, Heder J. de Vries, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sander Rigter, Evert-Jan Wils, Tim Frenzel, Dave A. Dongelmans, Remko de Jong, Marco A. A. Peters, Marlijn J. A. Kamps, Dharmanand Ramnarain, Ralph Nowitzky, Fleur G. C. A. Nooteboom, Wouter de Ruijter, Louise C. Urlings-Strop, Ellen G. M. Smit, D. Jannet Mehagnoul-Schipper, Tom Dormans, Cornelis P. C. de Jager, Stefaan H. A. Hendriks, Sefanja Achterberg, Evelien Oostdijk, Auke C. Reidinga, Barbara Festen-Spanjer, Gert B. Brunnekreef, Alexander D. Cornet, Walter van den Tempel, Age D. Boelens, Peter Koetsier, Judith Lens, Harald J. Faber, A. Karakus, Robert Entjes, Paul de Jong, Thijs C. D. Rettig, Sesmu Arbous, Sebastiaan J. J. Vonk, Tomas Machado, Willem E. Herter, Harm-Jan de Grooth, Patrick J. Thoral, Armand R. J. Girbes, Mark Hoogendoorn, Paul W. G. Elbers, The Dutch ICU Data Sharing Against COVID-19 Collaborators

Publikováno v: Annals of Intensive Care, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Background For mechanically ventilated critically ill COVID-19 patients, prone positioning has quickly become an important treatment strategy, however, prone positioning is labor intensive and comes with potential adverse effects. Therefore,

Externí odkaz: https://doaj.org/article/a3584c779f174b4ab55ecd74982c5e66

Predictors for extubation failure in COVID-19 patients using a machine learning approach

Autor: Lucas M. Fleuren, Tariq A. Dam, Michele Tonutti, Daan P. de Bruin, Robbert C. A. Lalisang, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sander Rigter, Evert-Jan Wils, Tim Frenzel, Dave A. Dongelmans, Remko de Jong, Marco Peters, Marlijn J. A. Kamps, Dharmanand Ramnarain, Ralph Nowitzky, Fleur G. C. A. Nooteboom, Wouter de Ruijter, Louise C. Urlings-Strop, Ellen G. M. Smit, D. Jannet Mehagnoul-Schipper, Tom Dormans, Cornelis P. C. de Jager, Stefaan H. A. Hendriks, Sefanja Achterberg, Evelien Oostdijk, Auke C. Reidinga, Barbara Festen-Spanjer, Gert B. Brunnekreef, Alexander D. Cornet, Walter van den Tempel, Age D. Boelens, Peter Koetsier, Judith Lens, Harald J. Faber, A. Karakus, Robert Entjes, Paul de Jong, Thijs C. D. Rettig, Sesmu Arbous, Sebastiaan J. J. Vonk, Mattia Fornasa, Tomas Machado, Taco Houwert, Hidde Hovenkamp, Roberto Noorduijn Londono, Davide Quintarelli, Martijn G. Scholtemeijer, Aletta A. de Beer, Giovanni Cinà, Adam Kantorik, Tom de Ruijter, Willem E. Herter, Martijn Beudel, Armand R. J. Girbes, Mark Hoogendoorn, Patrick J. Thoral, Paul W. G. Elbers, the Dutch ICU Data Sharing Against Covid-19 Collaborators

Publikováno v: Critical Care, Vol 25, Iss 1, Pp 1-10 (2021)

Abstract Introduction Determining the optimal timing for extubation can be challenging in the intensive care. In this study, we aim to identify predictors for extubation failure in critically ill patients with COVID-19. Methods We used highly granula

Externí odkaz: https://doaj.org/article/c04ef1ea0f0b493fb77ba8e33296e30c

Risk factors for adverse outcomes during mechanical ventilation of 1152 COVID-19 patients: a multicenter machine learning study with highly granular data from the Dutch Data Warehouse

Autor: Lucas M. Fleuren, Michele Tonutti, Daan P. de Bruin, Robbert C. A. Lalisang, Tariq A. Dam, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sebastiaan J. J. Vonk, Mattia Fornasa, Tomas Machado, Nardo J. M. van der Meer, Sander Rigter, Evert-Jan Wils, Tim Frenzel, Dave A. Dongelmans, Remko de Jong, Marco Peters, Marlijn J. A. Kamps, Dharmanand Ramnarain, Ralph Nowitzky, Fleur G. C. A. Nooteboom, Wouter de Ruijter, Louise C. Urlings-Strop, Ellen G. M. Smit, D. Jannet Mehagnoul-Schipper, Tom Dormans, Cornelis P. C. de Jager, Stefaan H. A. Hendriks, Evelien Oostdijk, Auke C. Reidinga, Barbara Festen-Spanjer, Gert Brunnekreef, Alexander D. Cornet, Walter van den Tempel, Age D. Boelens, Peter Koetsier, Judith Lens, Sefanja Achterberg, Harald J. Faber, A. Karakus, Menno Beukema, Robert Entjes, Paul de Jong, Taco Houwert, Hidde Hovenkamp, Roberto Noorduijn Londono, Davide Quintarelli, Martijn G. Scholtemeijer, Aletta A. de Beer, Giovanni Cinà, Martijn Beudel, Nicolet F. de Keizer, Mark Hoogendoorn, Armand R. J. Girbes, Willem E. Herter, Paul W. G. Elbers, Patrick J. Thoral, Dutch ICU Data Sharing Against COVID-19 Collaborators

Publikováno v: Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-15 (2021)

Abstract Background The identification of risk factors for adverse outcomes and prolonged intensive care unit (ICU) stay in COVID-19 patients is essential for prognostication, determining treatment intensity, and resource allocation. Previous studies

Externí odkaz: https://doaj.org/article/02fac2c9c60242bebdd4de7e0fafb6d2

Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

Autor: Tariq A. Dam, MD, Harm-Jan de Grooth, MD, PhD, Thomas Klausch, PhD, Lucas M. Fleuren, MD, Daan P. de Bruin, MSc, Robert Entjes, MD, Thijs C. D. Rettig, MD, PhD, Dave A. Dongelmans, MD, PhD, Age D. Boelens, MD, Sander Rigter, MD, Stefaan H. A. Hendriks, MD, Remko de Jong, MD, Marlijn J. A Kamps, MD, Marco Peters, MD, A. Karakus, MD, Diederik Gommers, MD, PhD, Dharmanand Ramnarain, MD, Evert-Jan Wils, MD, PhD, Sefanja Achterberg, MD, PhD, Ralph Nowitzky, MD, Walter van den Tempel, MD, Cornelis P. C. de Jager, MD, PhD, Fleur G. C. A. Nooteboom, MD, Evelien Oostdijk, MD, PhD, Peter Koetsier, MD, Alexander D. Cornet, MD, PhD, FRCP, Auke C. Reidinga, MD, Wouter de Ruijter, MD, PhD, Rob J. Bosman, MD, Tim Frenzel, MD, PhD, Louise C. Urlings-Strop, MD, PhD, Paul de Jong, MD, Ellen G. M. Smit, MD, Olaf L. Cremer, MD, PhD, D. Jannet Mehagnoul-Schipper, MD, PhD, Harald J. Faber, MD, Judith Lens, MD, Gert B. Brunnekreef, MD, Barbara Festen-Spanjer, MD, Tom Dormans, MD, PhD, Annemieke Dijkstra, MD, Bram Simons, MD, A. A. Rijkeboer, MD, Sesmu Arbous, MD, PhD, Marcel Aries, MD, PhD, Menno Beukema, MD, Daniël Pretorius, MD, Rutger van Raalte, MD, Martijn van Tellingen, MD, EDIC, Niels C. Gritters van den Oever, MD, Robbert C. A. Lalisang, MD, Michele Tonutti, MRes, Armand R. J. Girbes, MD, PhD, EDIC, Mark Hoogendoorn, PhD, Patrick J. Thoral, MD, EDIC, Paul W. G. Elbers, MD, PhD, EDIC, on behalf of the Dutch ICU Data Sharing Against COVID-19 Collaborators, Remko van den Akker, Tom A. Rijpstra, M. C. Reuland, Klaas Sierk Arnold, Arend Jan Meinders, Nicolas Schroten, Laura van Manen, Leon Montenij, Julia Koeter, J. W. Fijen, Jasper van Bommel, Roy van den Berg, Martha de Bruin, Roger van Rietschote, Ellen van Geest, Koen S. Simons, Anisa Hana, Joost Labout, Michael Kuiper, Albertus Beishuizen, Bart van de Gaauw, Roos Renckens, B. van den Bogaard, Peter Pickkers, Pim van der Heiden, Dennis Geutjes, Claudia (C. W.) van Gemeren, Emma Rademaker, Frits H. M. van Osch, Johan Lutisan, Jacomar J. M. van Koesveld, Bart P. Grady, Martijn de Kruif, Martin E. Haan, Luca Roggeveen, Dagmar M. Ouweneel, Ronald Driessen, Jan Peppink, G. J. Zijlstra, A. J. van Tienhoven, Evelien van der Heiden, Jan Jaap Spijkstra, Hans van der Spoel, Angelique de Man, Heder J. de Vries, Fuda van Diggelen, Ali el Hassouni, David Romero Guzman, Sandjai Bhulai, Sebastiaan J. J. Vonk, Mattia Fornasa, Tomas Machado, Adam Izdebski, Taco Houwert, Hidde Hovenkamp, Roberto Noorduijn Londono, Davide Quintarelli, Martijn G. Scholtemeijer, Aletta A. de Beer, Giovanni Cinà, Willem E. Herter, Michael de Neree tot Babberich, Olivier Thijssens, Lot Wagemakers, Hilde G. A. van der Pol, Tom Hendriks, Julie Berend, Virginia Ceni Silva, Robert F. J. Kullberg, Leo Heunks, Nicole Juffermans, Arjen J. C. Slooter, Martijn Beudel, Nicolet F. de Keizer

Publikováno v: Critical Care Explorations, Vol 3, Iss 10, p e0555 (2021)

OBJECTIVES:. As coronavirus disease 2019 is a novel disease, treatment strategies continue to be debated. This provides the intensive care community with a unique opportunity as the population of coronavirus disease 2019 patients requiring invasive m

Externí odkaz: https://doaj.org/article/32f239460e134af0a3cea6a1b4ef0a1c

Why physiology will continue to guide the choice between balanced crystalloids and normal saline: a systematic review and meta-analysis

Autor: Charlotte L. Zwager, Pieter Roel Tuinman, Harm-Jan de Grooth, Jos Kooter, Hans Ket, Lucas M. Fleuren, Paul W. G. Elbers

Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)

Abstract Background Crystalloids are the most frequently prescribed drugs in intensive care medicine and emergency medicine. Thus, even small differences in outcome may have major implications, and therefore, the choice between balanced crystalloids

Externí odkaz: https://doaj.org/article/99cfd8a4c10249c89798fed70df27ab5