Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lucas K. Kimerer"'
Publikováno v:
Journal of chromatography. A. 1655
The adsorption kinetics of a monoclonal antibody (mAb) used as a reference and of bivalent bispecific antibodies (BiSAb) on a macroporous cation exchanger is studied experimentally by examining the transient patterns of bound protein within the parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b04da1eebd7fcf0dd032332a6209c9
https://pubmed.ncbi.nlm.nih.gov/34461348
https://pubmed.ncbi.nlm.nih.gov/34461348
Publikováno v:
Journal of Chromatography A. 1601:121-132
The cation exchange chromatographic behavior of three homologous bivalent bispecific antibodies (BiSAb) is characterized for two different resins, Source 15S and ProPac WCX-10, having different base matrix, particle size, pore structure, and ligand c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb08027ae195f455240b34aef6d05c4
https://doi.org/10.1016/j.chroma.2019.04.012
https://doi.org/10.1016/j.chroma.2019.04.012
Publikováno v:
Journal of Chromatography A. 1601:133-144
In Part I of this work we determined the experimental cation exchange behavior of bivalent bispecific antibodies (BiSAb) comprising a pair of single chain variable fragment (scFv) domains flexibly linked to a framework immunoglobulin G (IgG), which e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c032ab4b786f81559f2c48cb8d87fb
https://doi.org/10.1016/j.chroma.2019.04.013
https://doi.org/10.1016/j.chroma.2019.04.013
Publikováno v:
Journal of Chromatography A. 1648:462181
The elution and adsorptive behavior of a bivalent bispecific antibody (BiSAb), comprising an IgG1 framework with a scFv domain genetically fused to each heavy chain C-terminus via flexible linkers, and of two associated fragments were studied on two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab6f2925a039483a67673581dec38e0
https://doi.org/10.1016/j.chroma.2021.462181
https://doi.org/10.1016/j.chroma.2021.462181
Publikováno v:
Journal of Chromatography A. 1628:461444
The effect of bead and ligand structure on protein adsorption was investigated for multimodal anion exchangers combining a quaternary ammonium ion group with hydrophobic moieties: Nuvia aPrime 1 and aPrime 2, based on a 54 μm diameter polymeric bead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb927cdff0a161b5fb0ebc26a29d71ef
https://doi.org/10.1016/j.chroma.2020.461444
https://doi.org/10.1016/j.chroma.2020.461444
Publikováno v:
Journal of Chromatography A. 1617:460836
The elution behavior of bivalent bispecific antibodies (BiSAb) comprising an immunoglobulin G framework genetically fused to a pair of single chain variable fragments (scFvs) was studied on hydrophobic interaction chromatography (HIC) columns using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfe17f819933f9007e4433ef99136aa
https://doi.org/10.1016/j.chroma.2019.460836
https://doi.org/10.1016/j.chroma.2019.460836
Autor:
John P. Fisher, Anthony J. Melchiorri, Laura G. Bracaglia, Lucas K. Kimerer, Narutoshi Hibino
A critical challenge to the success of biodegradable vascular grafts is the establishment of a healthy endothelium. To establish this monolayer of endothelial cells (ECs), a variety of techniques have been developed, including cell seeding. Vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da41c26b7e605568b0463dc5c6189c8c
https://europepmc.org/articles/PMC4943466/
https://europepmc.org/articles/PMC4943466/
Autor:
Yong-Ung Lee, Axel Krieger, Peter C.W. Kim, Anthony J. Melchiorri, C. A. Kraynak, Tai Yi, Narutoshi Hibino, Christopher K. Breuer, John P. Fisher, Cameron A. Best, Lucas K. Kimerer
Publikováno v:
Advanced healthcare materials. 5(3)
Although several strategies to three-dimensionally print cardiovascular grafts exist, these technologies either have required extensive culturing of cells on scaffolds prior to implantation to impart mechanical stability, necessitate additional fabri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd20a8b9c36b8152846007dfcc16e1d6
https://pubmed.ncbi.nlm.nih.gov/26627057
https://pubmed.ncbi.nlm.nih.gov/26627057