Výsledky vyhledávání - "Lucas J. Rudigier"

Akademický článek

Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation.

Autor: Lucas J Rudigier, Christof Dame, Holger Scholz, Karin M Kirschner

Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0176296 (2017)

Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the differentiation of the bipotential gonad into testes or ovaries. As such, the transcription factors WT1 and GATA4 are pivotal for prope

Externí odkaz: https://doaj.org/article/5720ce3c82924dc8bdac5479f46acffa

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Amine Oxidase Copper-containing 1 (AOC1) Is a Downstream Target Gene of the Wilms Tumor Protein, WT1, during Kidney Development

Autor: Karin M. Kirschner, Julian Braun, Charlotte Louise Justine Jacobi, Holger Scholz, Anja Bondke Persson, Lucas J. Rudigier

Publikováno v: Journal of Biological Chemistry. 289:24452-24462

Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcda067b1e599909fceee18409a03056
https://doi.org/10.1074/jbc.m114.564336

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Transcriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary development

Autor: Karin M. Kirschner, Charlotte Louise Justine Jacobi, Holger Scholz, Lucas J. Rudigier

ADAMTS16 (a disintegrin and metalloproteinase with thrombospondin motifs) is a secreted mammalian metalloproteinase with unknown function. We report here that murine Adamts16 is co-expressed with the Wilms tumor protein, Wt1, in the developing glomer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecef6f911a01dd9cf1ec4f2cefb2d8a
https://europepmc.org/articles/PMC4036291/

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