3D Spheroids Versus 3D Tumor-Like Microcapsules:Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells

Autor: Andreas Vierling, Mahshid Monavari, Özlem Ertekin, Aldo Leal-Egaña, Melanie Kappelmann-Fenzl, Kathrin Böpple, Anja K. Bosserhoff, Meng Dong, Lucas Höne, Gaëlle Letort, Paolo Ceppi, Beatrice Parma, Ralph Palmisano, Miguel Fuentes-Chandía, Sharmin Khan Antara, Aldo R. Boccaccini

Publikováno v: Fuentes-Chandía, M, Vierling, A, Kappelmann-Fenzl, M, Monavari, M, Letort, G, Höne, L, Parma, B, Antara, S K, Ertekin, Ö, Palmisano, R, Dong, M, Böpple, K, Boccaccini, A R, Ceppi, P, Bosserhoff, A K & Leal-Egaña, A 2021, ' 3D Spheroids Versus 3D Tumor-Like Microcapsules : Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells ', Advanced Biology, vol. 5, no. 7, 2000349 . https://doi.org/10.1002/adbi.202000349

As 2D surfaces fail to resemble the tumoral milieu, current discussions are focused on which 3D cell culture strategy may better lead the cells to express in vitro most of the malignant hints described in vivo. In this study, this question is assesse

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https://findresearcher.sdu.dk:8443/ws/files/184073112/adbi.202000349.pdf