Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lucas Germain"'
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 111053- (2024)
Prostate cancer is a hormone-dependent disease that relies on the androgen signaling, as well as on the estrogen signaling, for growth and survival. To identify the genes regulated by these sex-steroid hormones in the human prostate cancer cell line
Externí odkaz:
https://doaj.org/article/1c9b0d17e88247a6a797311b82c1b3d3
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 110870- (2024)
Sex hormones are necessary for the development and functions of the normal prostate as well as for the initiation and progression of prostate tumors. Indeed, androgens and estrogens can activate their respective nuclear receptors to modulate the expr
Externí odkaz:
https://doaj.org/article/07e531d60ca646a69deda108b8ce90a1
Autor:
Aurélie Lacouture, Yann Breton, Cindy Weidmann, Sarah-Maude Goulet, Lucas Germain, Martin Pelletier, Étienne Audet-Walsh
Publikováno v:
Environment International, Vol 179, Iss , Pp 108132- (2023)
Due to its sensitivity to hormonal signaling, the mammary gland is often referred to as a sentinel organ for the study of endocrine-disrupting chemicals (EDCs), environmental pollutants that can interfere with the estrogen signaling pathway and induc
Externí odkaz:
https://doaj.org/article/c6e49e9da0ff4b198fa3d6f11128e9e9
Autor:
Lucas Germain, Camille Lafront, Virginie Paquette, Bertrand Neveu, Jean-Sébastien Paquette, Frédéric Pouliot, Étienne Audet-Walsh
Publikováno v:
Nature Reviews Urology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8c102e26a7ff6bc91d273c9b45a7b3
https://doi.org/10.1038/s41585-023-00726-1
https://doi.org/10.1038/s41585-023-00726-1
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The estrogen signaling pathway has been reported to modulate prostate cancer (PCa) progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that selective estrogen receptor modulators (SERMs) are used to treat breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1651d0ec693acf52275588bbf14e23
http://link.springer.com/article/10.1038/s41598-020-60844-3
http://link.springer.com/article/10.1038/s41598-020-60844-3
Autor:
Cindy Weidmann, Étienne Audet-Walsh, Lucas Germain, Raghavendra Tejo Karthik Poluri, Jolyane Beaudette, Camille Lafront
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 202:105710
The androgen receptor (AR) is a transcription factor that drives prostate cancer (PCa) by modulating the expression of thousands of genes to promote proliferation and survival and to reprogram metabolism. However, how AR activation controls alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5800bf083541267f07ec2105b41e9fea
https://doi.org/10.1016/j.jsbmb.2020.105710
https://doi.org/10.1016/j.jsbmb.2020.105710
Autor:
Lucas Germain, Jolyane Beaudette, Cindy Weidmann, Raghavendra Tejo Karthik Poluri, Étienne Audet-Walsh, Camille Lafront
Publikováno v:
Cancer Research. 80:2083-2083
The androgen receptor (AR) is a transcription factor that drives prostate cancer (PCa) by modulating the expression of thousands of genes to promote proliferation and survival and to reprogram metabolism. However, how AR activation affects alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9ab1ec7e6d63e96dc39e3fe4a761a0
https://doi.org/10.1158/1538-7445.am2020-2083
https://doi.org/10.1158/1538-7445.am2020-2083
Publikováno v:
Cancer Research. 80:4361-4361
The estrogen receptors ERα and ERβ are expressed in prostate cancer (PCa) cells and are believed to act as an oncogene and a tumor suppressor, respectively, and thus to be attractive therapeutic targets. Indeed, compounds modulating the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b69e21cc793c55db4b71b5037ecbb6
https://doi.org/10.1158/1538-7445.am2020-4361
https://doi.org/10.1158/1538-7445.am2020-4361
