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pro vyhledávání: '"Lucas Donigan"'
Autor:
Kellie Pickell, Andrew Lam, Lucas Donigan, Marcus Fischer, Satyajit Sujit Kumar Mitra, Fumiko Takada Axelrod, Hoang Tran, Aurélie Chaudhari, In-Kyung Park, Christopher J. Bond, Austin L. Gurney, Timothy Hoey, Sanjeev Satyal, Aaron K. Sato, John Lewicki, Jennifer Cain, Cecile Chartier, Michelle Stroud, Sasha Lazetic, Ann M. Kapoun, May Ji, Wan-Ching Yen, Shirley Ma
Publikováno v:
Proceedings of the National Academy of Sciences. 109:11717-11722
The Wnt/β-catenin pathway, which signals through the Frizzled (Fzd) receptor family and several coreceptors, has long been implicated in cancer. Here we demonstrate a therapeutic approach to targeting the Wnt pathway with a monoclonal antibody, OMP-