Výsledky vyhledávání - "Lucas C, Olson"

Akademický článek

Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium

Autor: Kohei Togami, Whitney Wolf, Lucas C. Olson, Madison Card, Limei Shen, Alison Schaefer, Kenichi Okuda, Larry Zeitlin, Michael Pauly, Kevin Whaley, Raymond J. Pickles, Samuel K. Lai

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Effective treatment and immunoprophylaxis of viral respiratory infections with neutralizing monoclonal antibodies (mAbs) require maintaining inhibitory concentrations of mAbs at the airway surface. While engineered mAbs with increased affinity to the

Externí odkaz: https://doaj.org/article/1ce0586831914fc7af05bae7e4c1ab5f

Zobrazit plný text záznamu

Akademický článek

Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats

Autor: Kayla M. Scott, D. Joshua Cohen, Dane W. Nielson, Gloria Kim, Lucas C. Olson, Michael J. McClure, Mark W. Grinstaff, Barbara D. Boyan, Zvi Schwartz

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract Transfection of chondrocytes with microRNA-451(miR-451), present in growth zone cartilage of the growth plate, upregulates production of enzymes association with extracellular matrix degradation. miR-451 is also present in articular cartilag

Externí odkaz: https://doaj.org/article/608830619bb44b6d9f9ec9afd83cba45

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Human Adipose-Derived Stromal Cells Delivered on Decellularized Muscle Improve Muscle Regeneration and Regulate RAGE and P38 MAPK

Autor: Lucas C. Olson, James T. Redden, LaStar Gilliam, Tri M. Nguyen, Josephina A. Vossen, David J. Cohen, Zvi Schwartz, Michael J. McClure

Publikováno v: Bioengineering, Vol 9, Iss 9, p 426 (2022)

Volumetric muscle loss (VML) is the acute loss of muscle mass due to trauma. Such injuries occur primarily in the extremities and are debilitating, as there is no clinical treatment to restore muscle function. Pro-inflammatory advanced glycation end-

Externí odkaz: https://doaj.org/article/3ad6c3b77a304d0abca733b9aec8a4fd

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Advanced Glycation End-Products in Skeletal Muscle Aging

Autor: Lucas C. Olson, James T. Redden, Zvi Schwartz, David J. Cohen, Michael J. McClure

Publikováno v: Bioengineering, Vol 8, Iss 11, p 168 (2021)

Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia

Externí odkaz: https://doaj.org/article/e2d4a466b8d940f4bebd22c16eed01a3

Zobrazit plný text záznamu

Osseointegration and Remodeling of Mineralized Bone Graft Are Negatively Impacted by Prior Treatment with Bisphosphonates

Autor: D Joshua, Cohen, Christoph H, Lohmann, Kayla M, Scott, Lucas C, Olson, Barbara D, Boyan, Zvi, Schwartz

Publikováno v: J Bone Joint Surg Am

Bisphosphonates limit resorption by inhibiting osteoclast formation and activation. They are removed during preparation of demineralized bone matrix (DBM) particles, but it is not known if osteogenesis and incorporation of mineralized bone allografts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c20830b5c8e42af254a5042f8379169
https://doi.org/10.2106/jbjs.21.01489

Zobrazit plný text záznamu

Akademický článek

RNU (Foxn1RNU-Nude) Rats Demonstrate an Improved Ability to Regenerate Muscle in a Volumetric Muscle Injury Compared to Sprague Dawley Rats

Autor: Michael J. McClure, Lucas C. Olson, David J. Cohen, Yen Chen Huang, Shirley Zhang, Tri Nguyen, Barbara D. Boyan, Zvi Schwartz

Publikováno v: Bioengineering, Vol 8, Iss 1, p 12 (2021)

Products developed for skeletal muscle regeneration frequently incorporate allogeneic and xenogeneic materials to elicit a regenerative response to heal skeletal muscle wounds. To avoid graft rejection in preclinical studies, immunodeficient rodents

Externí odkaz: https://doaj.org/article/a5f8f4ed99b7466cbdb2fcd4334c5f50

Zobrazit plný text záznamu

Advanced Glycation End Products Are Retained in Decellularized Muscle Matrix Derived from Aged Skeletal Muscle

Autor: Lucas C. Olson, Zvi Schwartz, Barbara D. Boyan, Michael J. McClure, Tri Nguyen, Rebecca L. Heise

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8832, p 8832 (2021)

Decellularized tissues are biocompatible materials that engraft well, but the age of their source has not been explored for clinical translation. Advanced glycation end products (AGEs) are chemical cross-links that accrue on skeletal muscle collagen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9815babcd3ef283b10c236bc532347d

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání