Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lucas Antonio Pacheco"'
Autor:
Natália Marceli Stefanes, Nathalia Moreno Cury, Amanda Virtuoso Jacques, José Andrés Yunes, Ricardo José Nunes, Maria Cláudia Santos-Silva, Lucas Antonio Pacheco, Larissa Sens, Daiane Mari Perondi, Mariana Franzoni Maioral
Publikováno v:
Anti-cancer drugs. 30(8)
Acute leukemias are a heterogeneous group of aggressive malignant neoplasms associated with severe morbidities due to the nonselectivity of current chemotherapeutic drugs to nonmalignant cells. The investigation of novel natural and synthetic structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ccb10567758c7d31fcf9bb3545d978
https://pubmed.ncbi.nlm.nih.gov/30932944
https://pubmed.ncbi.nlm.nih.gov/30932944
Autor:
Laura Otto Walter, Iris Mattos Santos-Pirath, Ricardo José Nunes, Maria Cláudia Santos-Silva, Mariana Franzoni Maioral, Larissa Sens, Lucas Antonio Pacheco
Publikováno v:
Hematology/Oncology and Stem Cell Therapy, Vol 14, Iss 1, Pp 51-64 (2021)
The present study aimed to investigate the cytotoxic effect of 38 new thiosemicarbazone derivatives on hematological neoplastic cells lines and to select the most effective compounds to investigate the main molecular mechanisms involved in cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b95059d62e22edebcb6b5907ff7d5f7
https://pubmed.ncbi.nlm.nih.gov/32763229
https://pubmed.ncbi.nlm.nih.gov/32763229
Autor:
Mattia Mori, Larissa Sens, Ana Caroline Arruda de Souza, Ricardo José Nunes, Hernán Terenzi, Lucas Antonio Pacheco, Alessandra Mascarello, Angela C. O. Menegatti
Publikováno v:
Bioorganicmedicinal chemistry. 26(21)
Mycobacterium tuberculosis secretes two protein tyrosine phosphatases as virulence factors, PtpA and PtpB. Inhibition studies of these enzymes have shown significant attenuation of the M. tuberculosis growth in vivo. As PtpA mediates many effects on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d1ef33d6562142db7997552de63f91
https://pubmed.ncbi.nlm.nih.gov/30389409
https://pubmed.ncbi.nlm.nih.gov/30389409
Autor:
Domitila A. Huber, Darlan Bazilio, Flaviano Lorenzon, Lucas Antonio Pacheco, Janete Aparecida Anselmo-Franci, Sibele Sehnem, Fernanda B. Lima
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 25(7)
After menopause, hypertension elevates the risk of cardiac diseases, one of the major causes of women's morbidity. The gradual depletion of ovarian follicles in rats, induced by 4-vinylcyclohexene diepoxide (VCD), is a model for studying the physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b56029890ceeb22a619c488cba6abe2
https://pubmed.ncbi.nlm.nih.gov/29025323
https://pubmed.ncbi.nlm.nih.gov/29025323