Tb1, a Neurotoxin from Tityus bahiensis Scorpion Venom, Induces Epileptic Seizures by Increasing Glutamate Release

Autor: Emidio Beraldo Neto, Lucas Alves de Freitas, Daniel Carvalho Pimenta, Ivo Lebrun, Ana L. A. Nencioni

Publikováno v: Toxins, Vol 12, Iss 2, p 65 (2020)

Here, we report the neurotoxic effects aroused by the intracerebral injection (in rats) of Tb1, which is a neurotoxin isolated from Tityus bahiensis scorpion venom. Biochemical analyses have demonstrated that this toxin is similar to the gamma toxin

Externí odkaz: https://doaj.org/article/480009de66954c8e852d9513655bfca6

Expansão do Conhecimento e Inovação Tecnológica no Campo das Ciências Farmacêuticas

Autor: Talita Pinho Marcelino, Luana Guimarães Da Silva, Matheus Harllen Gonçalves Veríssimo, Rayssa Gabrielle Pereira De Castro Bueno, Aminata Doucoure Drame, Larissa Alves Assunção De Deus, Miriam Viviane Baron, Antônia Carla De Jesus Oliveira, Monara Henrique Dos Santos, Stéfani Ferreira De Oliveira, Morgana Maria Souza Gâdelha De Carvalho, S Mariah Andressa Gomes Da, Carla Isnara Menezes Vasconcelos, Flaviana Helena De Moraes Dos Santos, Tâmara Gabrielly Torres Silva, Mariah Andressa Gomes Da Silva, Matheus Andrade Rodrigues, Maria Clara Fontenele Da Cunha Melo, João Leonardo Rodrigues Mendonça Dias, Ingrid Freire Silva, Deyse Gabriele De Souza Gomes, Larissa Pires De Campos, Alex Bisoffi, Alana Sales Cavalcante, Douglas Siqueira De Almeida Chaves, Marília Melo Prado Cavalcante, Larissa Araújo Rolim, Gabriela Di Lorenzo Garcia Scherer, Francisca Melo Nascimento, P Paulo Celso, Caroline Amélia Gonçalves, Paulo Celso P, José Bruno Menezes Parente, Mayara Medeiros Lima De Oliveira, Mounike Rosa Santos, Myla Lôbo De Souza, Quezia Dos Santos Belarmino, Ianna Vasconcelos Feijão, Pedro José Rolim Neto, Beatriz Simone Monteiro De Melo, Marco Aurélio Ribeiro, Dyana Lemes Radinz, Ana Beatriz Lira, Renata Garcia Carneiro, Tibério Cesar Lima De Vasconcelos, Ana Valeska Costa Vasconcelos, Andres Felipe Mantilla Santamaria, Nicole Araújo Martins, Carolina Paz Mohamad Isa, Amanda Bastos Rocha, Maria Elenice Felício Pereira, Luis Manuel Ley Domínguez, Paulo Celso Pardi, Ieler Ferreira Ribeiro, Rosali Maria Ferreira Da Silva, Ana Kariny De Aguiar, Pollyne Amorim Silva, Neide Mara De Menezes Epifanio, Lanna Lidia Monteiro Figueiredo, Maria Isabel Araújo André Da Silva, Rodrigo Fonseca Lima, Flávia Regina Galvão De Sousa, Janine Koepp, Gustavo Alves Andrade Dos Santos, Débora Vanessa Bezerra Da Silva, Maria Alejandra Vallejo Rua, Iara Lúcia Tescarollo, Dalila Da Silva Sousa, Taysa Renata Ribeiro Timóteo, Alexandre Vaz Machado, Karina Da Silva Sousa, Rafaela Da Silva Mendes, Maria Ismaela Lima De Barros Dias, Lucas Alves De Freitas, Camila Sousa Cunha, Clévia De Sousa Rodrigues, Sergio De Mendonça, Linnel Estefania Padilla Guerrero, Annyelle Anastácio Cordeiro, Bartira Ercília Pinheiro Da Costa, Yasmim Christynne Oliveira Reis De Freitas, Maykon Jhuly Martins De Paiva, Antonia Carolina Melo Monteiro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1407c94c44b23f1fcfdd12975b2dac1
https://doi.org/10.22533/at.ed.061202109

ANEMIA HEMOLÍTICA AUTOIMUNE: INTRODUÇÃO Á FORMAS DE APRESENTAÇÃO DA SÍNDROME E DIAGNÓSTICO IMUNO-HEMATOLÓGICO

Autor: Rafaela da Silva Mendes, João Leonardo Rodrigues Mendonça Dias, Lucas Alves de Freitas, Paulo Celso Pardi, Sérgio de Mendonça, Luana Guimarães da Silva

Publikováno v: Expansão do Conhecimento e Inovação Tecnológica no Campo das Ciências Farmacêuticas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51d7c01f24215a1de6c657b0b031e42f
https://doi.org/10.22533/at.ed.0612021096

Tb1, a Neurotoxin from Tityus bahiensis Scorpion Venom, Induces Epileptic Seizures by Increasing Glutamate Release

Autor: Ivo Lebrun, Daniel C. Pimenta, Ana Leonor Abrahão Nencioni, Emidio Beraldo Neto, Lucas Alves de Freitas

Publikováno v: Toxins
Volume 12
Issue 2
Toxins, Vol 12, Iss 2, p 65 (2020)

Here, we report the neurotoxic effects aroused by the intracerebral injection (in rats) of Tb1, which is a neurotoxin isolated from Tityus bahiensis scorpion venom. Biochemical analyses have demonstrated that this toxin is similar to the gamma toxin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2781499220f61600643733011c2c2a4

Effects of Brazilian scorpion venoms on the central nervous system

Autor: Valquíria Abrão Coronado Dorce, Emidio Beraldo Neto, Lucas Alves de Freitas, Ana Leonor Abrahão Nencioni

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 0 (2018)
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 24, Article number: 3, Published: 22 FEB 2018
Journal of Venomous Animals and Toxins including Tropical Diseases v.24 2018
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP

In Brazil, the scorpion species responsible for most severe incidents belong to the Tityus genus and, among this group, T. serrulatus, T. bahiensis, T. stigmurus and T. obscurus are the most dangerous ones. Other species such as T. metuendus, T. silv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f1830f651544e07b40c686d27f4f7a
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100202&lng=en&tlng=en