Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lucas A. Gillenwater"'
Autor:
Tiffany J. Callahan, Ignacio J. Tripodi, Adrianne L. Stefanski, Luca Cappelletti, Sanya B. Taneja, Jordan M. Wyrwa, Elena Casiraghi, Nicolas A. Matentzoglu, Justin Reese, Jonathan C. Silverstein, Charles Tapley Hoyt, Richard D. Boyce, Scott A. Malec, Deepak R. Unni, Marcin P. Joachimiak, Peter N. Robinson, Christopher J. Mungall, Emanuele Cavalleri, Tommaso Fontana, Giorgio Valentini, Marco Mesiti, Lucas A. Gillenwater, Brook Santangelo, Nicole A. Vasilevsky, Robert Hoehndorf, Tellen D. Bennett, Patrick B. Ryan, George Hripcsak, Michael G. Kahn, Michael Bada, William A. Baumgartner, Lawrence E. Hunter
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-22 (2024)
Abstract Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face significant integration challenge
Externí odkaz:
https://doaj.org/article/2ba11bcf971c40478fb1f6a852218703
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Molecular “cartoons,” such as pathway diagrams, provide a visual summary of biomedical research results and hypotheses. Their ubiquitous appearance within the literature indicates their universal application in mechanistic communication. A recent
Externí odkaz:
https://doaj.org/article/d0f80cf8030242a6bd579af7800b152a
Autor:
Katherine A. Pratte, Jeffrey L. Curtis, Katerina Kechris, David Couper, Michael H. Cho, Edwin K. Silverman, Dawn L. DeMeo, Frank C. Sciurba, Yingze Zhang, Victor E. Ortega, Wanda K. O’Neal, Lucas A. Gillenwater, David A. Lynch, Eric A. Hoffman, John D. Newell, Alejandro P. Comellas, Peter J. Castaldi, Bruce E. Miller, Simon D. Pouwels, Nick H. T. ten Hacken, Rainer Bischoff, Frank Klont, Prescott G. Woodruff, Robert Paine, R. Graham Barr, John Hoidal, Claire M. Doerschuk, Jean-Paul Charbonnier, Ruby Sung, Nicholas Locantore, John G. Yonchuk, Sean Jacobson, Ruth Tal-singer, Debbie Merrill, Russell P. Bowler
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Soluble receptor for advanced glycation end products (sRAGE) is a proposed emphysema and airflow obstruction biomarker; however, previous publications have shown inconsistent associations and only one study has investigate the ass
Externí odkaz:
https://doaj.org/article/4e44582e7f784171ad0cc7e5e1a33440
Autor:
Lucas A. Gillenwater, Katerina J. Kechris, Katherine A. Pratte, Nichole Reisdorph, Irina Petrache, Wassim W. Labaki, Wanda O’Neal, Jerry A. Krishnan, Victor E. Ortega, Dawn L. DeMeo, Russell P. Bowler
Publikováno v:
Metabolites, Vol 11, Iss 3, p 161 (2021)
Susceptibility and progression of lung disease, as well as response to treatment, often differ by sex, yet the metabolic mechanisms driving these sex-specific differences are still poorly understood. Women with chronic obstructive pulmonary disease (
Externí odkaz:
https://doaj.org/article/3ff98a2fb40e4caf93e8cac0ac95ca5c
Autor:
Lucas A Gillenwater, Shahab Helmi, Evan Stene, Katherine A Pratte, Yonghua Zhuang, Ronald P Schuyler, Leslie Lange, Peter J Castaldi, Craig P Hersh, Farnoush Banaei-Kashani, Russell P Bowler, Katerina J Kechris
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255337 (2021)
Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of mortality in the United States; however, COPD has heterogeneous clinical phenotypes. This is the first large scale attempt which uses transcriptomics, proteomics, and metabolo
Externí odkaz:
https://doaj.org/article/720ad2983d46440eb08aaa313bff75a2
Autor:
Christine H. Wendt, Victor E. Ortega, Lucas A. Gillenwater, Yonghua Zhuang, Karan Uppal, Katherine A. Pratte, Gregory Michelotti, Russell P. Bowler, Wassim W. Labaki, Nichole Reisdorph, Michael H. Cho, Dean P. Jones, Wanda K. O'Neal, Katerina Kechris, Irina Petrache, Eitan Halper-Stromberg, Sean Jacobson, Charmion Cruickshank-Quinn, Brian D. Hobbs
Publikováno v:
Network and Systems Medicine
Background: Small studies have recently suggested that there are specific plasma metabolic signatures in chronic obstructive pulmonary disease (COPD), but there have been no large comprehensive study of metabolomic signatures in COPD that also integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb642b2ae32ea0e858a3d9e83a5f241e
http://europepmc.org/articles/PMC8109053
http://europepmc.org/articles/PMC8109053
Autor:
Frank Klont, John D. Newell, Ruth Tal-Singer, Wanda K. O'Neal, David Couper, Lucas A. Gillenwater, Jeffrey L. Curtis, Debbie Merrill, Robert Paine, Eric A. Hoffman, Peter J. Castaldi, Nicholas Locantore, Bruce E. Miller, Nick H. T. ten Hacken, Alejandro P. Comellas, David A. Lynch, Katherine A. Pratte, Yingze Zhang, Frank C. Sciurba, Russell P. Bowler, R. Graham Barr, Sean Jacobson, Victor E. Ortega, Simon D. Pouwels, Prescott G. Woodruff, Edwin K. Silverman, Dawn L. DeMeo, John R. Hoidal, Michael H. Cho, Katerina Kechris, John Yonchuk, Claire M. Doerschuk, Rainer Bischoff, Ruby Sung, Jean-Paul Charbonnier
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Respiratory Research, 22:127. BioMed Central Ltd.
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Respiratory Research, 22:127. BioMed Central Ltd.
Background Soluble receptor for advanced glycation end products (sRAGE) is a proposed emphysema and airflow obstruction biomarker; however, previous publications have shown inconsistent associations and only one study has investigate the association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bfb85f6d7456c933c8d989390c72d2
http://europepmc.org/articles/PMC8076883
http://europepmc.org/articles/PMC8076883
Autor:
Katherine A. Pratte, Jeffery L. Curtis, Katerina Kechris, David Couper, Michael H. Cho, Edwin K. Silverman, Dawn L. DeMeo, Frank C. Sciurba, Yingze Zhang, Victor E. Ortega, Wanda O'Neal, Lucas A. Gillenwater, David A. Lynch, Eric Hoffman, John D. Newell, Alejandro P. Comellas, Peter J. Castaldi, Bruce Miller, Simon D. Pouwels, Nick H.T. ten Hacken, Rainer Bischoff, Frank Klont, Prescott Woodruff, Robert Paine, R. Graham Barr, John Hoidal, Claire M. Doerschuk, Jean-Paul Charbonnier, Ruby Sung, Nick Locantore, John Yonchuk, Ruth Tal-Singer, Sean Jacobson, Debbie Merrill, Russell P. Bowler
Background:Soluble receptor for advanced glycation end products (sRAGE) is a proposed emphysema and airflow obstruction biomarker; however, previous publication have shown inconsistent associations and only one study has investigate the association b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da291315733bff3bac712ffa51327c7a
https://doi.org/10.21203/rs.3.rs-135754/v1
https://doi.org/10.21203/rs.3.rs-135754/v1
Autor:
Xiuqing Guo, Annette T. Hastie, Russell P. Bowler, Paul L. Auer, Elaine Cornell, Clary B. Clish, W. Craig Johnson, Alejandro P. Comellas, Michael Miller, Yongmei Liu, Stephen S. Rich, Debby Ngo, Claire M. Doerschuk, Victor E. Ortega, George J. Papanicolaou, Hong Dang, Alexander P. Reiner, Igor Barjaktarevic, Christine M. Freeman, Russell P. Tracy, Jerome I. Rotter, Kent D. Taylor, Peter Durda, Robert E. Gerszten, Lucas A. Gillenwater, Jeffrey L. Curtis, Claire Emson, Elizabeth J. Ampleford, Wassim W. Labaki, Katherine A. Pratte, Stephen P. Peters, Patricia V. Basta, Laura M. Raffield, Sean Jacobson, Gregory A. Hawkins, Julio Herrera, Wanda K. O'Neal, Brett Masters
Publikováno v:
Proteomics, vol 20, iss 12
Proteomics
Proteomics
Novel proteomics platforms, such as the aptamer-based SOMAscan platform, can quantify large numbers of proteins efficiently and cost-effectively and are rapidly growing in popularity. However, comparisons to conventional immunoassays remain underexpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a116c4f47776cf969b22cab0dfee6d83
https://escholarship.org/uc/item/69r5f1rm
https://escholarship.org/uc/item/69r5f1rm
Autor:
Varodom Charoensawan, Kelly S. Schweitzer, Lucas A. Gillenwater, Constance A. Griffin, Irina Bronova, David B. Pearse, Raluca Yonescu, Irina Petrache, Natalia I. Rush, Russel P. Bowler, Sonia M. Leach, Kevin Ni, Evgeny Berdyshev, Natini Jinawath
Publikováno v:
JCI Insight
Cigarette smoking (CS) and genetic susceptibility determine the risk for development, progression, and severity of chronic obstructive pulmonary diseases (COPD). We posited that an incidental balanced reciprocal chromosomal translocation was linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3447171943464b1ef966e36e0023c8b9
https://pubmed.ncbi.nlm.nih.gov/32573489
https://pubmed.ncbi.nlm.nih.gov/32573489