Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lucas, Huntimer"'
The mammosphere-derived epithelial cell secretome modulates neutrophil functions in the bovine model
Autor:
Rebecca M. Harman, Anja Sipka, Kelly A. Oxford, Leane Oliveira, Lucas Huntimer, Daryl V. Nydam, Gerlinde R. Van de Walle
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundInnovative therapies against bacterial infections are needed. One approach is to focus on host-directed immunotherapy (HDT), with treatments that exploit natural processes of the host immune system. The goals of this type of therapy are to
Externí odkaz:
https://doaj.org/article/80f27f40edfe4144bf907385cf17ee7f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The bovine mammary stem/progenitor cell secretome stimulates regeneration in vitro and contains proteins associated with antimicrobial defense. This has led to the exploration of the secretome as a biologic treatment for mastitis, a costly i
Externí odkaz:
https://doaj.org/article/ab2c29d22f6643e9a790049c1f3436a7
Autor:
Benjamin J. Evert, Shuxiong Chen, Robyn McConville, Ryan W. J. Steel, Julie Healer, Justin A. Boddey, Lucas Huntimer, Bernd H. A. Rehm
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of Plasmodium falciparum. This vaccine has limited efficacy, only preventing severe dise
Externí odkaz:
https://doaj.org/article/20819287a4164343b238a1a5bdf5f86f
Autor:
Ryan W.J. Steel, Shuxiong Chen, Lucas Huntimer, Benjamin Evert, Robyn McConville, Julie Healer, Justin A Boddey, Bernd H. A. Rehm
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
NPJ Vaccines
NPJ Vaccines
The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of Plasmodium falciparum. This vaccine has limited efficacy, only preventing severe disease in ab
Autor:
German Plata, Nielson T Baxter, Troy B Hawkins, Lucas Huntimer, Akshitha Nagireddy, Dwi Susanti, James B Reinbold
Liver abscesses caused by polymicrobial infections of the liver are a widespread problem in feedlot cattle production. There are currently no effective methods for the early detection of liver abscesses or to predict antibiotic efficacy. Although gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ee4fce71f83ce6b8b95cc8f5e74128
https://doi.org/10.1101/2022.09.16.508319
https://doi.org/10.1101/2022.09.16.508319
Autor:
Kelly Lechtenberg, Lucas Huntimer, Shollie M. Falkenberg, Jamie Henningson, Tom Halbur, Ben M. Hause
Publikováno v:
Veterinary Microbiology
Highlights • The emerging influenza D virus (IDV) caused respiratory disease in calves. • A homologous inactivated vaccine was immunogenic and partially protective. • IDV titers in vaccinated calves were significantly reduced compared to contro
Autor:
Adams, Michael J. Wannemuehler, Kathleen A. Ross, Marian L. Kohut, Kevin L. Legge, Susan Carpenter, Mallapragadal Sk, Vela Ramirez Je, Lucas Huntimer, Tatiana K. Bronich, Balaji Narasimhan, Webby R
Publikováno v:
Journal of Biomedical Nanotechnology. 10:2261-2294
The potential epidemiological human pandemic resulting from highly pathogenic avian influenza (HPAI) H5N1 has been studied extensively since the identification of the virus in the Guangdong province of China. The majority of research has focused on t
Autor:
Michael J. Wannemuehler, Balaji Narasimhan, Amanda E. Ramer-Tait, Ross J. Darling, Kathleen A. Ross, Lucas Huntimer, Nicole E. Winterwood, Paola M. Boggiatto
Publikováno v:
TECHNOLOGY. :171-175
Polyanhydride nanoparticle-based vaccines (or nanovaccines) stabilize protein antigens, provide sustained antigen release leading to prolonged antigen presence, enhance activation of antigen presenting cells, and elicit protective immunity against re
Autor:
Lucas Huntimer, Hyelee Loyd, Balaji Narasimhan, Kathleen A. Ross, Michael J. Wannemuehler, Wuwei Wu, Susan Carpenter
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:4161-4168
Although H5N1 avian influenza has not yet acquired the capacity to readily infect humans, should it do so, this viral pathogen would present an increasing threat to the immunologically naive human population. Subunit vaccines based on the viral glyco
Autor:
Lynn Pruisner, Amanda E. Ramer-Tait, Lucas Huntimer, Kathleen A. Ross, Balaji Narasimhan, Chong Wang, Brenda R. Carrillo-Conde, Michael J. Wannemuehler, Jennifer H. Wilson Welder
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :91-98
Microparticle adjuvants based on biodegradable polyanhydrides were used to provide controlled delivery of a model antigen, ovalbumin (Ova), to mice. Ova was encapsulated into two different polyanhydride microparticle formulations to evaluate the infl