Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Lucas, Delmonico"'
1
Akademický článek
Nuclear and Cytoplasmic hTERT, Tumor-Infiltrating Lymphocytes, and Telomere Elongation Leukocytes Are Independent Factors in the Response to Neoadjuvant Treatment in HER2-Enriched Breast Cancer
Autor: Lucas Delmonico, José Bines, Cristina Moreira do Nascimento, Priscila Valverde Fernandes, Isabel de Souza Barbosa, Gabriel Brito Ribeiro, Bruno Henrique Rala de Paula, Rafaele Tavares Silvestre, Maria Helena Faria Ornellas, Gilda Alves, Claudia Lage
Publikováno v: Current Oncology, Vol 30, Iss 4, Pp 4094-4109 (2023)
HER2-enriched tumors are responsible for 20% of breast tumors and have high rates of immune infiltrates in the tumor stroma that respond favorably to neoadjuvant chemotherapy. In the context of tumors, telomeres control cell death and prevent tumor c
Externí odkaz: https://doaj.org/article/195f53b77b8641b1b1ab533c54b4fbd1
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2
Akademický článek
Clinical applications of liquid biopsy in HPV-negative and HPV-positive head and neck squamous cell carcinoma: advances and challenges
Autor: Mariana Chantre-Justino, Gilda Alves, Lucas Delmonico
Publikováno v: Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 4, Pp 533-552 (2022)
Head and neck squamous cell carcinomas (HNSCCs) represent the most common epithelial tumors that arise from mucosa of the oral cavity, pharynx, and larynx. The development of HNSCCs is usually associated with tobacco use, alcohol consumption, and hum
Externí odkaz: https://doaj.org/article/ae94857ecc694498bfc1b4255651d632
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3
Akademický článek
The contribution of the 20th century discoveries on the circulating DNA as biomarkers for cancer screening
Autor: GILDA ALVES, MARIANA CHANTRE, LUCAS DELMONICO
Publikováno v: Anais da Academia Brasileira de Ciências, Vol 92, Iss 4 (2020)
Abstract Circulating DNA can be released in the biological fluids by a physiological process and by different pathological conditions. The first reports detecting circulating DNA in human plasma date from the late 40s. Even when specific pathological
Externí odkaz: https://doaj.org/article/03dc3c0f45a24267816eedc7a6ebcc8d
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4
Tracking the history of circulating nucleic acids for cancer research in Brazil: A systematic review
Autor: Mariana Chantre-Justino, Lucas Delmonico, Claudia Lage, Maria G. C. Carvalho, Maria Helena F. Ornellas, Gilda Alves
Publikováno v: Brazilian Journal of Health and Biomedical Sciences. 20:135-143
Introduction: Circulating nucleic acids can be obtainedby minimally invasive procedures based on liquid biopsy,which has emerged as a promising area of investigation forscreening and monitoring cancer treatment. Currently, testsbased on circulating n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee9e81bfdc41997f38bae1382bbf5bc4
https://doi.org/10.12957/bjhbs.2021.63966
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5
Akademický článek
A Novel Panel of 80 RNA Biomarkers with Differential Expression in Multiple Human Solid Tumors against Healthy Blood Samples
Autor: Lucas Delmonico, John C. Obenauer, Fatir Qureshi, Gilda Alves, Mauricio Augusto Silva Magalhães Costa, Katherine J. Martin, Marcia V. Fournier
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 19, p 4894 (2019)
The aim of this study was to identify genes with higher expression in solid tumor cells by comparing human tumor biopsies with healthy blood samples using both in silico statistical analysis and experimental validations. This approach resulted in a n
Externí odkaz: https://doaj.org/article/b0ce3e0201a44c88848ef11366f73481
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6
Overview of germline variants in the BRCA2 gene in cohort of Brazilian women with a high risk of hereditary breast cancer
Autor: Renata Mendes de Freitas, Gilda Alves, Maximiliano Ribeiro Guerra, Angélica Atala Lombelo Campos, Lucas Delmonico, Pedro Henrique de Oliveira Medeiros, Rafaela Russi Ervilha, Jane Rocha Duarte Cintra, Maria Teresa Bustamante Teixeira
Publikováno v: Mastology. 32
Introduction: Malignant breast cancer is the second most common type of cancer among women in the world, leaving behind nonmelanoma skin cancer. The aim of this study was to identify germline variants in the BRCA1 and BRCA2 genes in women diagnosed w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d65dd6fc6ca8ace1ef78948b50ca1df
https://doi.org/10.29289/2594539420220003
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8
Housekeeping genes involved in non-malignant breast phenotypes are widely expressed in multiple cancers and provide novel biomarkers of tumor classification
Autor: John C. Obenauer, Marcia V. Fournier, T.P. Stockfisch, Lucas Delmonico
Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 54, Iss 7 (2021)
Brazilian Journal of Medical and Biological Research v.54 n.7 2021
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 54, Issue: 7, Article number: e10388, Published: 17 MAY 2021
Clinically relevant biomarkers are useful to determine cancer patients' prognosis and treatments. To discover new putative biomarkers, we performed in silico analysis of a 325-gene panel previously associated with breast epithelial cell biology and c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005fb451b90f2e2e1fc796698abca9a5
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000700603&tlng=en
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9
Akademický článek
Detecção dos Polimorfismos 213A→G e 13494G→A no Gene TP53 em Carcinoma Ductal in situ de Mama: Relato de Caso
Autor: Lucas Delmonico, Lívia Menezes, Marco Felipe Franco Rosa, Najla Marques de Oliveira Mattar, Eliane Barbosa Esteves, Vivian Rabello Areias, Carolina Maria de Azevedo, Gilda Alves
Publikováno v: Revista Brasileira de Cancerologia, Vol 59, Iss 3 (2013)
Introdução: A caracterização das alterações moleculares em lesões mamárias suspeitas para malignidade ainda não são bem definidas. Sabe-se que a detecção precoce do câncer de mama aumenta consideravelmente as chances de cura. Com isso, a
Externí odkaz: https://doaj.org/article/142b9b9437d64a95918e5be767f1c4b1
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10
Hypermethylation in Gene Promoters Are Induced by Chronic Exposure to Benzene, Toluene, Ethylbenzene and Xylenes
Autor: Maria Helena Ornellas, Lucas Delmonico, Gilda Alves, Mariana Chantre-Justino, Fábio Santiago, Rafaele Tavares Silvestre, Ubirani Barros Otero, Maryah Bravo, Thomas Liehr, Luciano Rios Scherrer
Publikováno v: Pakistan journal of biological sciences : PJBS. 23(4)
BACKGROUND AND OBJECTIVE Gas station attendants are occupationally exposed to benzene, toluene, ethylbenzene and xylene (BTEX) compounds and thus more susceptible to the biological effects of this mixture present in gasoline, especially due to the ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bac92d6a521b2691b113bcd40724f79
https://pubmed.ncbi.nlm.nih.gov/32363837
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