Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Luca Urbani"'
Publikováno v:
Frontiers in Chemical Engineering, Vol 6 (2024)
Externí odkaz:
https://doaj.org/article/4251ebb4489c47c58664aabbb53efdf7
Autor:
Sara Campinoti, Bruna Almeida, Negin Goudarzi, Stefan Bencina, Fabio Grundland Freile, Claire McQuitty, Dipa Natarajan, I Jane Cox, Adrien Le Guennec, Vamakshi Khati, Giulia Gaudenzi, Roberto Gramignoli, Luca Urbani
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Congenital and chronic liver diseases have a substantial health burden worldwide. The most effective treatment available for these patients is whole organ transplantation; however, due to the severely limited supply of donor livers and the side effec
Externí odkaz:
https://doaj.org/article/05fffb292181404e835f376efabe862e
Autor:
Edward Hannon, Marco Pellegrini, Federico Scottoni, Natalie Durkin, Soichi Shibuya, Roberto Lutman, Toby J. Proctor, J. Ciaran Hutchinson, Owen J. Arthurs, Demetra-Ellie Phylactopoulos, Elizabeth F. Maughan, Colin R. Butler, Simon Eaton, Mark W. Lowdell, Paola Bonfanti, Luca Urbani, Paolo De Coppi
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105174- (2022)
Summary: Decellularization of esophagi from several species for tissue engineering is well described, but successful implantation in animal models of esophageal replacement has been challenging. The purpose of this study was to assess feasibility and
Externí odkaz:
https://doaj.org/article/e4991bd0c49541dc872eda47ebf1df19
Autor:
Giovanni Giuseppe Giobbe, Claire Crowley, Camilla Luni, Sara Campinoti, Moustafa Khedr, Kai Kretzschmar, Martina Maria De Santis, Elisa Zambaiti, Federica Michielin, Laween Meran, Qianjiang Hu, Gijs van Son, Luca Urbani, Anna Manfredi, Monica Giomo, Simon Eaton, Davide Cacchiarelli, Vivian S. W. Li, Hans Clevers, Paola Bonfanti, Nicola Elvassore, Paolo De Coppi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Organoid cultures have been developed from multiple tissues, opening new possibilities for regenerative medicine. Here the authors demonstrate the derivation of GMP-compliant hydrogels from decellularized porcine small intestine which support formati
Externí odkaz:
https://doaj.org/article/a28b06f5539f456b97162079de3a5a5a
Autor:
Caterina Trevisan, Mario Enrique Alvrez Fallas, Edoardo Maghin, Chiara Franzin, Piero Pavan, Paola Caccin, Angela Chiavegato, Eugenia Carraro, Daniele Boso, Francesco Boldrin, Federico Caicci, Enrica Bertin, Luca Urbani, Anna Milan, Carlo Biz, Lorenza Lazzari, Paolo De Coppi, Michela Pozzobon, Martina Piccoli
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 858-869 (2019)
Abstract Surgical repair of large muscular defects requires the use of autologous graft transfer or prosthetic material. Naturally derived matrices are biocompatible materials obtained by tissue decellularization and are commonly used in clinical pra
Externí odkaz:
https://doaj.org/article/0c15f6c5e94d46a09d8dc058cfbfa131
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chronic liver disease when accompanied by underlying fibrosis, is characterized by an accumulation of extracellular matrix (ECM) proteins and chronic inflammation. Although traditionally considered as a passive and largely architectural structure, th
Externí odkaz:
https://doaj.org/article/25bbdc8de3a34c04bee7af4159553911
Autor:
Luca Urbani, Carlotta Camilli, Demetra-Ellie Phylactopoulos, Claire Crowley, Dipa Natarajan, Federico Scottoni, Panayiotis Maghsoudlou, Conor J. McCann, Alessandro Filippo Pellegata, Anna Urciuolo, Koichi Deguchi, Sahira Khalaf, Salvatore Ferdinando Aruta, Maria Cristina Signorelli, David Kiely, Edward Hannon, Matteo Trevisan, Rui Rachel Wong, Marc Olivier Baradez, Dale Moulding, Alex Virasami, Asllan Gjinovci, Stavros Loukogeorgakis, Sara Mantero, Nikhil Thapar, Neil Sebire, Simon Eaton, Mark Lowdell, Giulio Cossu, Paola Bonfanti, Paolo De Coppi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Combining decellularised scaffolds with patient-derived cells holds promise for bioengineering of functional tissues. Here the authors develop a two-stage approach to engineer an oesophageal graft that retains the structural organisation of native oe
Externí odkaz:
https://doaj.org/article/04035db7e1a6472b9d4fc0a2bd25b51a
Autor:
Anna Urciuolo, Luca Urbani, Silvia Perin, Panagiotis Maghsoudlou, Federico Scottoni, Asllan Gjinovci, Henry Collins-Hooper, Stavros Loukogeorgakis, Athanasios Tyraskis, Silvia Torelli, Elena Germinario, Mario Enrique Alvarez Fallas, Carla Julia-Vilella, Simon Eaton, Bert Blaauw, Ketan Patel, Paolo De Coppi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-20 (2018)
Abstract Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric muscle loss (VML). Therapeutic approaches involving acellular matrices represent an emerging and promising strategy to promote regeneration of ske
Externí odkaz:
https://doaj.org/article/60c000f05b17423389276b399e8a2068
Autor:
Giuseppe Mazza, Walid Al-Akkad, Andrea Telese, Lisa Longato, Luca Urbani, Benjamin Robinson, Andrew Hall, Kenny Kong, Luca Frenguelli, Giusi Marrone, Oliver Willacy, Mohsen Shaeri, Alan Burns, Massimo Malago, Janet Gilbertson, Nigel Rendell, Kevin Moore, David Hughes, Ioan Notingher, Gavin Jell, Armando Del Rio Hernandez, Paolo De Coppi, Krista Rombouts, Massimo Pinzani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The development of human liver scaffolds retaining their 3-dimensional structure and extra-cellular matrix (ECM) composition is essential for the advancement of liver tissue engineering. We report the design and validation of a new methodolo
Externí odkaz:
https://doaj.org/article/32ff58339b1d4b9d8761dceb964446e2
Autor:
Lisa Sassi, Omolola Ajayi, Sara Campinoti, Dipa Natarajan, Claire McQuitty, Riccardo Rayan Siena, Sara Mantero, Paolo De Coppi, Alessandro F. Pellegata, Shilpa Chokshi, Luca Urbani
Publikováno v:
Nanomaterials, Vol 11, Iss 2, p 275 (2021)
In the field of in vitro liver disease models, decellularised organ scaffolds maintain the original biomechanical and biological properties of the extracellular matrix and are established supports for in vitro cell culture. However, tissue engineerin
Externí odkaz:
https://doaj.org/article/11bac9c84485474eb852cec2630c0fb5