Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Luca Tiberi"'
Autor:
Foteini Tsiami, Chiara Lago, Noemi Pozza, Federica Piccioni, Xuesong Zhao, Fabienne Lülsberg, David E. Root, Luca Tiberi, Marcel Kool, Jens Schittenhelm, Pratiti Bandopadhayay, Rosalind A. Segal, Ghazaleh Tabatabai, Daniel J. Merk
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Sonic hedgehog subgroup of medulloblastoma (SHH-MB) is characterized by aberrant activation of the SHH signaling pathway. An inhibition of the positive SHH regulator Smoothened (SMO) has demonstrated promising clinical efficacy. Yet, primary
Externí odkaz:
https://doaj.org/article/1081383d8a884e1bb850b117fd782524
Autor:
Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methyl
Externí odkaz:
https://doaj.org/article/3e271e6514f4435baadb82be0810cbf5
Autor:
Daniela Michelatti, Sven Beyes, Chiara Bernardis, Maria Luce Negri, Leonardo Morelli, Naiara Garcia Bediaga, Vittoria Poli, Luca Fagnocchi, Sara Lago, Sarah D’Annunzio, Nicole Cona, Ilaria Gaspardo, Aurora Bianchi, Jovana Jovetic, Matteo Gianesello, Alice Turdo, Caterina D’Accardo, Miriam Gaggianesi, Martina Dori, Mattia Forcato, Giuliano Crispatzu, Alvaro Rada-Iglesias, Maria Soledad Sosa, H. T. Marc Timmers, Silvio Bicciato, Matilde Todaro, Luca Tiberi, Alessio Zippo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Metastasis arises from disseminated tumour cells (DTCs) that are characterized by intrinsic phenotypic plasticity and the capability of seeding to secondary organs. DTCs can remain latent for years before giving rise to symptomatic overt met
Externí odkaz:
https://doaj.org/article/f053b57e57204e48bf78051e5364cb8f
Autor:
Luca Tiberi
Publikováno v:
Bibliothecae.it, Vol 12, Iss 2, Pp 3-201 (2023)
In this paper we deal with some XVII and XVIII centuries studies on the Library of Alexandria. Some of the most important contributions here considered are André Schott’s corollarium to the Lipsius’s Syntagma (1606), Gronovius’ Exercitationes
Externí odkaz:
https://doaj.org/article/c0ed9f9346cc42828f2d9450c1a43f9e
Autor:
Chiara Lago, Aniello Federico, Gloria Leva, Norman L Mack, Benjamin Schwalm, Claudio Ballabio, Matteo Gianesello, Luana Abballe, Isabella Giovannoni, Sofia Reddel, Sabrina Rossi, Nicolas Leone, Andrea Carai, Angela Mastronuzzi, Alessandra Bisio, Alessia Soldano, Concetta Quintarelli, Franco Locatelli, Marcel Kool, Evelina Miele, Luca Tiberi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-28 (2023)
Abstract Brain tumors are the leading cause of cancer‐related death in children. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of pediatric brain cancers are limited and hard to establish. We present a p
Externí odkaz:
https://doaj.org/article/27709dc824264046a65fac5ef01127a4
Autor:
Francesco Antonica, Lucia Santomaso, Davide Pernici, Linda Petrucci, Giuseppe Aiello, Alessandro Cutarelli, Luciano Conti, Alessandro Romanel, Evelina Miele, Toma Tebaldi, Luca Tiberi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Pediatric and adult high-grade gliomas are the most common primary malignant brain tumors, with poor prognosis due to recurrence and tumor infiltration after therapy. Quiescent cells have been implicated in tumor recurrence and treatment res
Externí odkaz:
https://doaj.org/article/43efb7b47c3b48e68e112be0007905f9
Autor:
Luca Tiberi
Publikováno v:
Bibliothecae.it, Vol 11, Iss 1, Pp 7-39 (2022)
On the basis of Strabo’s and Athenaeus’ well known passages (Geograph., XIII, 1, 54, 5-9, Deipnosoph. I, 4, 22-33 and V, 53, 1-11) on the Aristoteles’ books, their arrival to Alexandria has to be considered as a turning point in the history of
Externí odkaz:
https://doaj.org/article/d2ae2c76c7a1450f9f2d6255eb2c74b2
Autor:
Luca Tiberi
Publikováno v:
Bibliothecae.it, Vol 9, Iss 2, Pp 4-100 (2020)
This paper (first of two parts) aims to gather the most important testimonies of modern age authors regarding the Library of Alexandria, so that can be observed how the fire in 47 b.C. is considered. The increasing knowledge of the classical texts im
Externí odkaz:
https://doaj.org/article/8683322a958e4334b487c67ffc506bf1
Autor:
Francesco Antonica, Giuseppe Aiello, Alessia Soldano, Luana Abballe, Evelina Miele, Luca Tiberi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Brain tumors are a large and heterogeneous group of neoplasms that affect the central nervous system and include some of the deadliest cancers. Almost all the conventional and new treatments fail to hinder tumoral growth of the most malignant brain t
Externí odkaz:
https://doaj.org/article/d212cfface8d4363a9fafa5fb7aeb36c
Autor:
Claudio Ballabio, Marica Anderle, Matteo Gianesello, Chiara Lago, Evelina Miele, Marina Cardano, Giuseppe Aiello, Silvano Piazza, Davide Caron, Francesca Gianno, Andrea Ciolfi, Lucia Pedace, Angela Mastronuzzi, Marco Tartaglia, Franco Locatelli, Elisabetta Ferretti, Felice Giangaspero, Luca Tiberi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Medulloblastoma (MB) is the most common malignant brain tumor in children and among the subtypes, Group 3 MB has the worst outcome. Here, we perform an in vivo, patient-specific screen leading to the identification of Otx2 and c-MYC as stron
Externí odkaz:
https://doaj.org/article/9519a8f838f84cd89a2a82dbc13a35e4