Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Luca Rovatti"'
Publikováno v:
Organic Process Research & Development. 14:840-848
GV143253A 1 is a broad-spectrum injectable β-lactam belonging to the class of trinem antibiotics. This article describes the work which enabled a detailed process understanding via several analytical techniques and the subsequent optimization of a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::550956663d2dccfed589e253f7c68396
https://doi.org/10.1021/op100097c
https://doi.org/10.1021/op100097c
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:156-163
A number of recent studies have demonstrated that peroxynitrite (ONOO−) can react with a host of biomolecules, particularly those containing aromatic amino acid residues, resulting in a number of modifications which have been found in association w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46090df39d1995cfd1b1c893e813413
https://doi.org/10.1002/(sici)1097-0231(19990215)13:3<156::aid-rcm472>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990215)13:3<156::aid-rcm472>3.0.co
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:1494-1500
Complexation of acrylamide with bovine beta-lactoglobulin B and some of its tryptic fragments have been examined by liquid chromatography coupled to tandem mass spectrometry. Such complexation was investigated both in the presence and in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea03d9f8ff83f1ad9b02ef2d81918ab
https://doi.org/10.1002/(sici)1097-0231(19981030)12:20<1494::aid-rcm354>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19981030)12:20<1494::aid-rcm354>3.0.co
Publikováno v:
Journal of Chromatography A. 819:133-142
This work describes the use of multi-stage liquid chromatography–electrospray mass spectrometry to characterise four potential degradation products associated with a suspension containing a newly synthesised β-lactam antibacterial compound. Initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3abef394775015bd9d8ca089c47f7ef6
https://doi.org/10.1016/s0021-9673(98)00485-3
https://doi.org/10.1016/s0021-9673(98)00485-3
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:484-488
Adduction between acrylamide and cysteine residues is a post-translational modification associated with proteins separated by gel electrophoresis. In the present article, three model peptides containing 2-4 cysteine residues were reduced with dithiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed7402a0d3d8ce4ab5e0e06a47b3273
https://doi.org/10.1002/(sici)1097-0231(19980430)12:8<484::aid-rcm185>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19980430)12:8<484::aid-rcm185>3.0.co
Investigation of bombolitin complexes with mercury by liquid chromatography/tandem mass spectrometry
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:61-68
Solid-phase synthesis of (Cys)bombolitin peptide resulted in a crude reaction mixture containing the target peptide as well as a number of unknown products. The use of on-line liquid chromatography coupled to electrospray mass spectrometry (LC/ES-MS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f3e87b0a722510415a368ca7a3d5275
https://doi.org/10.1002/(sici)1097-0231(19980131)12:2<61::aid-rcm117>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19980131)12:2<61::aid-rcm117>3.0.co
Publikováno v:
Rapid Communications in Mass Spectrometry. 10:1739-1742
beta(1-39) amyloid peptide is one of the components of the cerebral amyloid deposits that are characteristic of Alzheimer's disease. Solid-phase synthesis of this peptide resulted in a fairly complex crude product containing both the target peptide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1eb0671b236632e42065c80d464b674
https://doi.org/10.1002/(sici)1097-0231(199611)10:14<1739::aid-rcm759>3.0.co
https://doi.org/10.1002/(sici)1097-0231(199611)10:14<1739::aid-rcm759>3.0.co
Autor:
Mahmoud Hamdan, Luca Rovatti, Ersilia Cassano, Ornella Curcuruto, Paolo Rovero, Claudia Galoppini
Publikováno v:
Rapid Communications in Mass Spectrometry. 10:1504-1508
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b667b0118b97ba15fbe2b1c9640067
https://doi.org/10.1002/(sici)1097-0231(199609)10:12<1504::aid-rcm640>3.0.co
https://doi.org/10.1002/(sici)1097-0231(199609)10:12<1504::aid-rcm640>3.0.co
Autor:
Luca Rovatti, Lucilla Turco, Arianna Ribecai, Sergio Bacchi, Stefano Provera, Damiano Papini, Anna Mingardi, Simone Guelfi, Sebastiano Mozzo, Carla Marchioro, Alberto Spezzaferri
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 53(3)
A multi-technique approach was applied in order to fully characterize four low-level unknown impurities of GW876008, a novel CRF(1) receptor antagonist. Liquid chromatography (LC)-NMR spectroscopy was used in combination with LC-MS to obtain detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff54ac3c7c4c6ffe716540af5b293d8
https://pubmed.ncbi.nlm.nih.gov/20619567
https://pubmed.ncbi.nlm.nih.gov/20619567
Publikováno v:
Journal of chromatography. A. 1004(1-2)
The small (Mr = 11729) serum protein beta2-microglobulin is prone to precipitate as amyloid in a protein conformational disorder (PCD) that occurs in a significant number of patients on chronic hemodialysis. Analyses by capillary electrophoresis (CE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07dea0bed4225fb0932b0227f58fde4
https://pubmed.ncbi.nlm.nih.gov/12929961
https://pubmed.ncbi.nlm.nih.gov/12929961