Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Luca Rosario La Rosa"'
Autor:
Manuela Santonocito, Cristina Zappulla, Santa Viola, Luca Rosario La Rosa, Elena Solfato, Ilenia Abbate, Valeria Tarallo, Ivana Apicella, Chiara Bianca Maria Platania, Grazia Maugeri, Velia D’Agata, Claudio Bucolo, Sandro De Falco, Maria Grazia Mazzone, Francesco Giuliano
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4404 (2021)
Eye drop formulations allowing topical treatment of retinal pathologies have long been sought as alternatives to intravitreal administration. This study aimed to assess whether a novel nanostructured microemulsions system (NaMESys) could be usefully
Externí odkaz:
https://doaj.org/article/593cdf1fe0e64801a43c5888ecdbed9a
Autor:
Luca Rosario La Rosa, Lorena ePerrone, Morten Schallburg Nielsen, Pietro eCalissano, Olav Michael Andersen, Carmela eMatrone
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
The intracellular transport and localization of amyloid precursor protein (APP) are critical determinants of APP processing and β-amyloid peptide production, thus crucially important for the pathophysiology of Alzheimer’s disease (AD). Notably, th
Externí odkaz:
https://doaj.org/article/05eb7aa0e4f14d18ba4e139a66781372
Autor:
Andrea Sudano Roccaro, Carmela Giovanna Spoto, Luca Rosario La Rosa, Claudine Civiale, Manuela Santonocito, Santa Viola, Cristina Zappulla, Maria Cristina Curatolo, Maria Grazia Mazzone
Publikováno v:
Eye Diseases-Recent Advances, New Perspectives and Therapeutic Options
Eye Diseases-Recent Advances, New Perspectives and Therapeutic Options ISBN: 9781803564166
Eye Diseases-Recent Advances, New Perspectives and Therapeutic Options ISBN: 9781803564166
Netilmicin is a potent and safe antibiotic with a very low incidence of resistance used as a topical ophthalmic medication in bacterial ocular infections. The aim of this study was to compare netilmicin’s Quotient of Inhibitions (QIs) and killing k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0147e68d2f8ef7bf7b486ad29a17fc1a
https://mts.intechopen.com/articles/show/title/potency-of-netilmicin-against-staphylococci-compared-to-other-ophthalmic-antibiotics
https://mts.intechopen.com/articles/show/title/potency-of-netilmicin-against-staphylococci-compared-to-other-ophthalmic-antibiotics
Autor:
Ilenia Abbate, Cristina Zappulla, Manuela Santonocito, Santa Viola, Luca Rosario La Rosa, Giuseppe De Pasquale, Elisa Caviola, Marisa Meloni, Maria Cristina Curatolo, Maria Grazia Mazzone
Publikováno v:
Experimental eye research. 222
Dry eye disease (DED), a multifactorial disease of the tears and ocular system, causes loss of tear film homeostasis with damage to the ocular surface. This study aimed to assess whether a peculiar matrix based on sodium hyaluronate (HA), xanthan gum
Autor:
Valeria Tarallo, Sandro De Falco, Claudio Bucolo, Elena Solfato, Ilenia Abbate, Grazia Maugeri, Luca Rosario La Rosa, Francesco Giuliano, Santa Viola, Cristina Zappulla, Velia D'Agata, Maria Grazia Mazzone, Manuela Santonocito, Chiara Bianca Maria Platania, Ivana Apicella
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4404, p 4404 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 9
International journal of molecular sciences
22 (2021). doi:10.3390/ijms22094404
info:cnr-pdr/source/autori:Santonocito M.; Zappulla C.; Viola S.; Rosa L.R.L.; Solfato E.; Abbate I.; Tarallo V.; Apicella I.; Platania C.B.M.; Maugeri G.; D'agata V.; Bucolo C.; De Falco S.; Mazzone M.G.; Giuliano F./titolo:Assessment of a new nanostructured microemulsion system for ocular delivery of sorafenib to posterior segment of the eye/doi:10.3390%2Fijms22094404/rivista:International journal of molecular sciences (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:22
International Journal of Molecular Sciences
Volume 22
Issue 9
International journal of molecular sciences
22 (2021). doi:10.3390/ijms22094404
info:cnr-pdr/source/autori:Santonocito M.; Zappulla C.; Viola S.; Rosa L.R.L.; Solfato E.; Abbate I.; Tarallo V.; Apicella I.; Platania C.B.M.; Maugeri G.; D'agata V.; Bucolo C.; De Falco S.; Mazzone M.G.; Giuliano F./titolo:Assessment of a new nanostructured microemulsion system for ocular delivery of sorafenib to posterior segment of the eye/doi:10.3390%2Fijms22094404/rivista:International journal of molecular sciences (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:22
Eye drop formulations allowing topical treatment of retinal pathologies have long been sought as alternatives to intravitreal administration. This study aimed to assess whether a novel nanostructured microemulsions system (NaMESys) could be usefully
Autor:
Luca Rosario La Rosa, Viviana Triaca, Marsha Pellegrino, Valentina Sposato, Carla Petrella, Pietro Calissano, Fabiola Moretti, Andrea Levi, Maria Teresa Ciotti, Ilaria Pagano, Nadia Canu, Delio Mercanti, Ichiro N. Maruyama
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in molecular neuroscience 10 (2017). doi:10.3389/fnmol.2017.00015
info:cnr-pdr/source/autori:Canu, Nadia; Pagano, Ilaria; La Rosa, Luca Rosario; Pellegrino, Marsha; Ciotti, Maria Teresa; Mercanti, Delio; Moretti, Fabiola; Sposato, Valentina; Triaca, Viviana; Petrella, Carla; Maruyama, Ichiro N.; Levi, Andrea; Calissano, Pietro/titolo:Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents/doi:10.3389%2Ffnmol.2017.00015/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Frontiers in molecular neuroscience 10 (2017). doi:10.3389/fnmol.2017.00015
info:cnr-pdr/source/autori:Canu, Nadia; Pagano, Ilaria; La Rosa, Luca Rosario; Pellegrino, Marsha; Ciotti, Maria Teresa; Mercanti, Delio; Moretti, Fabiola; Sposato, Valentina; Triaca, Viviana; Petrella, Carla; Maruyama, Ichiro N.; Levi, Andrea; Calissano, Pietro/titolo:Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents/doi:10.3389%2Ffnmol.2017.00015/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain tissue but not in Alzheimer's disease (AD) brain tissue. However, it has not been reported whether the two proteins inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd659d8bd3f9a1466421a12cdc13e27
http://hdl.handle.net/2108/172310
http://hdl.handle.net/2108/172310
Autor:
Giulia Ferrari-Toninelli, Andrea Mastinu, Luca Rosario La Rosa, Stefania Mitola, Maurizio Memo, Sara Anna Bonini, Mariagrazia Grilli, Marika Premoli, Giuseppina Maccarinelli
Publikováno v:
Cerebral Cortex (New York, NY)
Alterations in genes that regulate neurodevelopment can lead to cortical malformations, resulting in malfunction during postnatal life. The NF-κB pathway has a key role during neurodevelopment by regulating the maintenance of the neural progenitor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbbb128bc9a5c132ab7d46262938c45
http://hdl.handle.net/11379/478302
http://hdl.handle.net/11379/478302
Autor:
Morten Nielsen, Olav M. Andersen, Carmela Matrone, Lorena Perrone, Luca Rosario La Rosa, Pietro Calissano
Publikováno v:
La Rosa, L R, Perrone, L, Nielsen, M S, Calissano, P, Andersen, O M & Matrone, C 2015, ' Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction ', Frontiers in Cellular Neuroscience, vol. 9, pp. 109 . https://doi.org/10.3389/fncel.2015.00109
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 9 (2015)
The intracellular transport and localization of amyloid precursor protein (APP) are critical determinants of APP processing and β-amyloid peptide production, thus crucially important for the pathophysiology of Alzheimer's disease (AD). Notably, the
Autor:
Luca Rosario La Rosa, Siro Luvisetto, Annabella Pignataro, Franco Lombino, Martine Ammassari-Teule, Hui Zheng, Fabrizio Biundo, Luciano D'Adamio, Carmela Matrone, Robert Tamayev, Li Yang, Nadia Canu, Alessia P. M. Barbagallo
Publikováno v:
Aging cell
11 (2012): 1084–1093. doi:10.1111/acel.12009
info:cnr-pdr/source/autori:Carmela Matrone 1,2; Siro Luvisetto 1; Luca R. La Rosa 1; Robert Tamayev 3; Annabella Pignataro 1,4; Nadia Canu 1,5; Li Yang 6; Alessia P. M. Barbagallo 3; Fabrizio Biundo 3; Franco Lombino 3; Hui Zheng 6; Martine Ammassari-Teule 1,4; Luciano D'Adamio 3/titolo:Tyr682 in the Abeta-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance/doi:10.1111%2Facel.12009/rivista:Aging cell (Print)/anno:2012/pagina_da:1084/pagina_a:1093/intervallo_pagine:1084–1093/volume:11
Matrone, C, Luvisetto, S, La Rosa, L R, Tamayev, R, Pignataro, A, Canu, N, Yang, L, Barbagallo, A P M, Biundo, F, Lombino, F, Zheng, H, Ammassari-Teule, M & D'Adamio, L 2012, ' Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance ', Aging Cell . https://doi.org/10.1111/acel.12009
11 (2012): 1084–1093. doi:10.1111/acel.12009
info:cnr-pdr/source/autori:Carmela Matrone 1,2; Siro Luvisetto 1; Luca R. La Rosa 1; Robert Tamayev 3; Annabella Pignataro 1,4; Nadia Canu 1,5; Li Yang 6; Alessia P. M. Barbagallo 3; Fabrizio Biundo 3; Franco Lombino 3; Hui Zheng 6; Martine Ammassari-Teule 1,4; Luciano D'Adamio 3/titolo:Tyr682 in the Abeta-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance/doi:10.1111%2Facel.12009/rivista:Aging cell (Print)/anno:2012/pagina_da:1084/pagina_a:1093/intervallo_pagine:1084–1093/volume:11
Matrone, C, Luvisetto, S, La Rosa, L R, Tamayev, R, Pignataro, A, Canu, N, Yang, L, Barbagallo, A P M, Biundo, F, Lombino, F, Zheng, H, Ammassari-Teule, M & D'Adamio, L 2012, ' Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance ', Aging Cell . https://doi.org/10.1111/acel.12009
Processing of Abeta-precursor protein (APP) plays an important role in Alzheimer's disease (AD) pathogenesis. The APP intracellular domain contains residues important in regulating APP function and processing, in particular the (682) YENPTY(687) moti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7757f065e76cf29ed804a076004aa48c
https://publications.cnr.it/doc/192197
https://publications.cnr.it/doc/192197
Autor:
Luca Rosario La Rosa, Fulvio Florenzano, Pietro Calissano, Moses V. Chao, Carmela Matrone, Maria Teresa Ciotti, Alessia P. M. Barbagallo, Luciano D'Adamio, Delio Mercanti
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(33)
The pathogenic model of Alzheimer's disease (AD) posits that aggregates of amyloid β, a product of amyloid precursor protein (APP) processing, cause dementia. However, alterations of normal APP functions could contribute to AD pathogenesis, and it i