Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model

Autor: Tommaso Vannocci, Roberto Notario Manzano, Ombretta Beccalli, Barbara Bettegazzi, Fabio Grohovaz, Gianfelice Cinque, Antonio de Riso, Luca Quaroni, Franca Codazzi, Annalisa Pastore

Publikováno v: Disease Models & Mechanisms, Vol 11, Iss 6 (2018)

The neurodegenerative disease Friedreich's ataxia is caused by lower than normal levels of frataxin, an important protein involved in iron–sulfur (Fe-S) cluster biogenesis. An important step in designing strategies to treat this disease is to under

Externí odkaz: https://doaj.org/article/16551d903a38406a8e868659ead73a77

Understanding and Controlling Spatial Resolution, Sensitivity, and Surface Selectivity in Resonant-Mode Photothermal-Induced Resonance Spectroscopy

Autor: Luca Quaroni

Publikováno v: Analytical Chemistry

Photothermal-induced resonance (PTIR) is increasingly used in the measurement of infrared absorption spectra of submicrometer objects. The technique measures IR absorption spectra by relying on the photothermal effect induced by a rapid pulse of ligh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7c78837b095596a8f1cf7c8616fede
https://doi.org/10.1021/acs.analchem.9b03468

Imaging and Spectroscopy of Domains of the Cellular Membrane by Photothermal-Induced Resonance

Autor: Luca Quaroni

We use photothermal induced resonance (PTIR) imaging and spectroscopy, in resonant and non-resonant mode, to study the cytoplasmic membrane and surface of intact cells. Non-resonant PTIR images apparently provide rich details of the cell surface. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a0bf2aa53e65e9a8397b72388ed9fb

Infrared and 2-Dimensional Correlation Spectroscopy Study of the Effect of CH

Autor: Luca, Quaroni, Iness, Benmessaoud, Bertrand, Vileno, Endre, Horváth, László, Forró

Publikováno v: Molecules

We studied the effect of the exposure of human A549 and SH-SY5Y cell lines to aqueous solutions of organic/inorganic halide perovskites CH3NH3PbI3 (MAPbI3) and CH3NH3SnI3 (MASnI3) at the molecular level by using Fourier transform infrared microspectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf2f12ed63a59875ddd34b7a9caea114
https://pubmed.ncbi.nlm.nih.gov/31947578

Label-Free, Real-Time Measurement of Metabolism of Adherent and Suspended Single Cells by In-Cell Fourier Transform Infrared Microspectroscopy

Autor: Giulia Milordini, Magda Wolna, Antonio de Riso, Annalisa Pastore, Luca Quaroni, Gianfelice Cinque, Tommaso Vannocci

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10742, p 10742 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19

We used infrared (IR) microscopy to monitor in real-time the metabolic turnover of individual mammalian cells in morphologically different states. By relying on the intrinsic absorption of mid-IR light by molecular components, we could discriminate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6239d97604e339623267ccf78a0253ff
https://doi.org/10.3390/ijms221910742