Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Luca Pozzetti"'
1
Akademický článek
Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals
Autor: Luca Pozzetti, Francesca Ferrara, Ludovica Marotta, Sandra Gemma, Stefania Butini, Mascia Benedusi, Fabio Fusi, Amer Ahmed, Serena Pomponi, Stefano Ferrari, Matteo Perini, Anna Ramunno, Giacomo Pepe, Pietro Campiglia, Giuseppe Valacchi, Gabriele Carullo, Giuseppe Campiani
Publikováno v: Antioxidants, Vol 11, Iss 3, p 437 (2022)
Extra virgin olive oil (EVOO) is the typical source of fats in the Mediterranean diet. While fatty acids are essential for the EVOO nutraceutical properties, multiple biological activities are also due to the presence of polyphenols. In this work, au
Externí odkaz: https://doaj.org/article/e4dd718fa3f647b1a83b6d23bbac0bac
Zobrazit plný text záznamu
2
Akademický článek
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity
Autor: Luca Pozzetti, Roberta Ibba, Sara Rossi, Orazio Taglialatela-Scafati, Donatella Taramelli, Nicoletta Basilico, Sarah D’Alessandro, Silvia Parapini, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Publikováno v: Molecules, Vol 27, Iss 2, p 463 (2022)
The potential of natural and synthetic chalcones as therapeutic leads against different pathological conditions has been investigated for several years, and this class of compounds emerged as a privileged chemotype due to its interesting anti-inflamm
Externí odkaz: https://doaj.org/article/c71fd374e78544d7896e5a872a2d6b87
Zobrazit plný text záznamu
3
Akademický článek
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)
Autor: Giacomo Rossino, Marta Rui, Luca Pozzetti, Dirk Schepmann, Bernhard Wünsch, Daniele Zampieri, Giorgia Pellavio, Umberto Laforenza, Silvia Rinaldi, Giorgio Colombo, Laura Morelli, Pasquale Linciano, Daniela Rossi, Simona Collina
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 20, p 7708 (2020)
Sigma-1 receptor (S1R) is a promising molecular target for the development of novel effective therapies against neurodegenerative diseases. To speed up the discovery of new S1R modulators, herein we report the development of a reliable in silico prot
Externí odkaz: https://doaj.org/article/05b98dd1459c4ac992880c7886a816b9
Zobrazit plný text záznamu
4
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy
Autor: Giuseppe Campiani, Tuhina Khan, Cristina Ulivieri, Leopoldo Staiano, Chiara Papulino, Stefania Magnano, Seema Nathwani, Anna Ramunno, Daniel Lucena-Agell, Nicola Relitti, Stefano Federico, Luca Pozzetti, Gabriele Carullo, Alice Casagni, Simone Brogi, Francesca Vanni, Paola Galatello, Magda Ghanim, Niamh McCabe, Stefania Lamponi, Massimo Valoti, Ola Ibrahim, Jeffrey O'Sullivan, Richard Turkington, Vincent P. Kelly, Ruben VanWemmel, J. Fernando Díaz, Sandra Gemma, Daniela Zisterer, Lucia Altucci, Maria Antonietta De Matteis, Stefania Butini, Rosaria Benedetti
Publikováno v: Campiani, G, Khan, T, Ulivieri, C, Staiano, L, Papulino, C, Magnano, S, Nathwani, S, Ramunno, A, Lucena-Agell, D, Relitti, N, Federico, S, Pozzetti, L, Carullo, G, Casagni, A, Brogi, S, Vanni, F, Galatello, P, Ghanim, M, McCabe, N, Lamponi, S, Valoti, M, Ibrahim, O, O'Sullivan, J, Turkington, R, Kelly, V P, VanWemmel, R, Díaz, J F, Gemma, S, Zisterer, D, Altucci, L, De Matteis, A, Butini, S & Benedetti, R 2022, ' Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy ', European journal of medicinal chemistry . https://doi.org/10.1016/j.ejmech.2022.114274
Digital.CSIC. Repositorio Institucional del CSIC
instname
96 p.-20 fig.-7 tab.
Autophagy is a lysosome dependent cell survival mechanism and is central to the maintenance of organismal homeostasis in both physiological and pathological situations. Targeting autophagy in cancer therapy attracted conside
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ef89cb959aee76e9472906938463af
http://hdl.handle.net/11386/4802551
Zobrazit plný text záznamu
5
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity
Autor: Sandra Gemma, SILVIA PARAPINI, Giuseppe Campiani, Donatella Taramelli, Roberta Ibba, Stefania Butini, Luca Pozzetti, Sarah D'Alessandro, Orazio Taglialatela-Scafati, Sara Rossi, Nicoletta Basilico
Publikováno v: Molecules
Molecules, Vol 27, Iss 463, p 463 (2022)
Molecules; Volume 27; Issue 2; Pages: 463
The potential of natural and synthetic chalcones as therapeutic leads against different pathological conditions has been investigated for several years, and this class of compounds emerged as a privileged chemotype due to its interesting anti-inflamm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27e79d172182012239815485d2452ba
http://hdl.handle.net/11365/1185724
Zobrazit plný text záznamu
7
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
Autor: Fulvio Saccoccia, Luca Pozzetti, Roberto Gimmelli, Stefania Butini, Alessandra Guidi, Giuliana Papoff, Marialaura Giannaccari, Simone Brogi, Viviana Scognamiglio, Sandra Gemma, Giovina Ruberti, Giuseppe Campiani
Publikováno v: Journal of Biological Chemistry. 298:102375
Parasitic diseases cause significant global morbidity and mortality particularly in the poorest regions of the world. Schistosomiasis, one of the most widespread neglected tropical diseases, affects more than 200 million people worldwide. Histone dea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb2c221ce8dde8a3f8f2487784b34eb
https://doi.org/10.1016/j.jbc.2022.102375
Zobrazit plný text záznamu
9
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)
Autor: Silvia Rinaldi, Daniele Zampieri, Giorgio Colombo, Marta Rui, Giacomo Rossino, Pasquale Linciano, Daniela Rossi, Umberto Laforenza, Giorgia Pellavio, Simona Collina, Dirk Schepmann, Laura Morelli, Bernhard Wünsch, Luca Pozzetti
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7708, p 7708 (2020)
Sigma-1 receptor (S1R) is a promising molecular target for the development of novel effective therapies against neurodegenerative diseases. To speed up the discovery of new S1R modulators, herein we report the development of a reliable in silico prot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fd75eef696c64d2af3770810e60b30
http://europepmc.org/articles/PMC7589021
Zobrazit plný text záznamu
10
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists
Autor: Stefania Butini, Nicola Relitti, Giuseppe Campiani, Luca Pozzetti, Sandra Gemma, Gabriele Carullo, Alessandro Papa, Stefano Federico
Publikováno v: Journal of medicinal chemistry. 63(22)
Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs), and they are involved in the regulation of innate immune system. These transmembrane r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17400bc432ec2b00ba0c96f8f5bb8340
https://pubmed.ncbi.nlm.nih.gov/32845153
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje