Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Luca Posa"'
Autor:
Mackenzie C. Gamble, Benjamin R. Williams, Navsharan Singh, Luca Posa, Zachary Freyberg, Ryan W. Logan, Stephanie Puig
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Despite the prevalence of opioid misuse, opioids remain the frontline treatment regimen for severe pain. However, opioid safety is hampered by side-effects such as analgesic tolerance, reduced analgesia to neuropathic pain, physical dependence, or re
Externí odkaz:
https://doaj.org/article/585f4542de6e47da906dfef65e3d5feb
Autor:
Laura Rullo, Francesca Felicia Caputi, Loredana Maria Losapio, Camilla Morosini, Luca Posa, Donatella Canistro, Fabio Vivarelli, Patrizia Romualdi, Sanzio Candeletti
Publikováno v:
Molecules, Vol 27, Iss 23, p 8321 (2022)
Opioids are the most effective drugs used for the management of moderate to severe pain; however, their chronic use is often associated with numerous adverse effects. Some results indicate the involvement of oxidative stress as well as of proteasome
Externí odkaz:
https://doaj.org/article/b4bb08af702d49c29c391d1037bd1bba
Autor:
Yadong Ji, Chimdiya Onwukwe, Jesse Smith, Hanna Laub, Luca Posa, Asaf Keller, Radi Masri, Nathan Cramer
The parabrachial complex (PB) is critically involved in aversive processes, and chronic pain is associated with amplified activity of PB neurons in rodent models of neuropathic pain. Here we demonstrate that catecholaminergic input from the caudal nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1d0ca5c57b07e08bcbdad743cebf9a
https://doi.org/10.1101/2022.09.29.510103
https://doi.org/10.1101/2022.09.29.510103
Autor:
Luca Posa, Danilo De Gregorio, Martha Lopez‐Canul, Qianzi He, Emmanuel Darcq, Laura Rullo, Leora Pearl‐Dowler, Livio Luongo, Sanzio Candeletti, Patrizia Romualdi, Brigitte Lina Kieffer, Gabriella Gobbi
Publikováno v:
Journal of Pineal Research. 73
Autor:
Luca, Posa, Danilo, De Gregorio, Martha, Lopez-Canul, Qianzi, He, Emmanuel, Darcq, Laura, Rullo, Leora, Pearl-Dowler, Livio, Luongo, Sanzio, Candeletti, Patrizia, Romualdi, Brigitte Lina, Kieffer, Gabriella, Gobbi
Publikováno v:
Journal of pineal researchREFERENCES. 73(4)
Melatonin, through its G protein-coupled receptor (GPCR) (MTNR1B gene) MT
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. :110805
Autor:
Luca Posa, Sophia A. Miracle, Ashley K. McDonald, Kathryn M. Albers, Zachary Freyberg, Ryan W. Logan, Stephanie Puig
Publikováno v:
The Journal of Pain. 24:34
Autor:
Marco Caprini, Luca Posa, Sanzio Candeletti, Rocco Liguori, Francesca Felicia Caputi, Francesco Formaggio, Patrizia Romualdi, Laura Rullo, Serena Stamatakos
Publikováno v:
Brain research bulletin. 175
Fabry disease (FD) is an X-linked inherited disorder characterized by glycosphingolipid accumulation due to deficiency of α-galactosidase A (α-Gal A) enzyme. Chronic pain and mood disorders frequently coexist in FD clinical setting, however underly
Autor:
Antonio Inserra, Justine P Enns, Luca Posa, Jelena Popic, He Qianzi, Agnieszka Skalecka, Danilo De Gregorio, Argel Aguilar-Valles, Christopher K. Lafferty, Athanasios Markopoulos, Martha Lopez-Canul, Jonathan P. Britt, Nahum Sonenberg, Stefano Comai, Gabriella Gobbi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Social behavior (SB) is a fundamental hallmark of human interaction. Repeated administration of low doses of the 5-HT2A agonist lysergic acid diethylamide (LSD) in mice enhances SB by potentiating 5-HT2A and AMPA receptor neurotransmissi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8415a277385cb4078e956e1374d984
Autor:
Francesca Felicia Caputi, Danilo De Gregorio, Matthew Kaba Aboud, Martha Lopez-Canul, Luca Posa, Gabriella Gobbi, Sanzio Candeletti, Patrizia Romualdi, Sergio Dominguez-Lopez, Laura Rullo
Publikováno v:
Journal of Pineal Research. 69
Melatonin, a neurohormone that binds to two G protein-coupled receptors MT1 and MT2, is involved in pain regulation, but the distinct role of each receptor has yet to be defined. We characterized the nociceptive responses of mice with genetic inactiv