Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Luca Ponzoni"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007749 (2020)
The renal outer medullary potassium (ROMK) channel is essential for potassium transport in the kidney, and its dysfunction is associated with a salt-wasting disorder known as Bartter syndrome. Despite its physiological significance, we lack a mechani
Externí odkaz:
https://doaj.org/article/0487c1f81a1847eaa979102ea2265a93
Autor:
Yong Wan, Zhihua Liu, Ivet Bahar, Kun-Liang Guan, Yi Huang, Mingjing He, Rui Zhu, Aiping Luo, Luca Ponzoni, Honghong Zhou, Zhuan Zhou
Tab S1 Mass spectry proteins report of F/H-EIF3H purification. Tab S2 Characteristics of breast invasive ductal carcinoma patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af2abf0d4f0a2033703fd344741d5d5
https://doi.org/10.1158/0008-5472.22423098.v1
https://doi.org/10.1158/0008-5472.22423098.v1
Autor:
Yong Wan, Zhihua Liu, Ivet Bahar, Kun-Liang Guan, Yi Huang, Mingjing He, Rui Zhu, Aiping Luo, Luca Ponzoni, Honghong Zhou, Zhuan Zhou
Fig.S1 EIF3H promotes EMT and tumor invasion. Fig.S2 Clinico-pathological correlations of EIF3H. Fig.S3 Lys63-linked tetra-ubiquitin in-vitro cleavage assay. Fig.S4 GST Pull-down assay. Fig.S5 EIF3H binds to YAP1 and stabilizes YAP1. Fig.S6 EIF3H act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149e6295f38e32b3fd7d983062a3c3f7
https://doi.org/10.1158/0008-5472.22423101.v1
https://doi.org/10.1158/0008-5472.22423101.v1
Autor:
Yong Wan, Zhihua Liu, Ivet Bahar, Kun-Liang Guan, Yi Huang, Mingjing He, Rui Zhu, Aiping Luo, Luca Ponzoni, Honghong Zhou, Zhuan Zhou
Supplement methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50698ce813d88252df9b98704d3bc9d1
https://doi.org/10.1158/0008-5472.22423104.v1
https://doi.org/10.1158/0008-5472.22423104.v1
Autor:
Yong Wan, Zhihua Liu, Ivet Bahar, Kun-Liang Guan, Yi Huang, Mingjing He, Rui Zhu, Aiping Luo, Luca Ponzoni, Honghong Zhou, Zhuan Zhou
EIF3H is presumed to be a critical translational initiation factor. Here, our unbiased screening for tumor invasion factors has identified an unexpected role for EIF3H as a deubiquitylating enzyme that dictates breast tumor invasion and metastasis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4e26dfbc80aae0b15cd3fe6404d7831
https://doi.org/10.1158/0008-5472.c.6511425.v1
https://doi.org/10.1158/0008-5472.c.6511425.v1
Autor:
Luca Ponzoni, Giulia Rossetti, Luca Maggi, Alejandro Giorgetti, Paolo Carloni, Cristian Micheletti
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 2, p e1005381 (2017)
G protein-coupled receptors (GPCRs) are the largest superfamily of signaling proteins. Their activation process is accompanied by conformational changes that have not yet been fully uncovered. Here, we carry out a novel comparative analysis of intern
Externí odkaz:
https://doaj.org/article/bcbd196f5408458a8c03a2fa29b86b29
Autor:
Mingjing He, Zhihua Liu, Yong Wan, Rui Zhu, Kun-Liang Guan, Honghong Zhou, Ivet Bahar, Luca Ponzoni, Aiping Luo, Yi Huang, Zhuan Zhou
Publikováno v:
Cancer Res
EIF3H is presumed to be a critical translational initiation factor. Here, our unbiased screening for tumor invasion factors has identified an unexpected role for EIF3H as a deubiquitylating enzyme that dictates breast tumor invasion and metastasis by
Publikováno v:
Bioinformatics
Motivation The biological effects of human missense variants have been studied experimentally for decades but predicting their effects in clinical molecular diagnostics remains challenging. Available computational tools are usually based on the analy
Autor:
Alexandre V. Fassio, Laura Shub, Luca Ponzoni, Jessica McKinley, Matthew J. O’Meara, Rafaela S. Ferreira, Michael J. Keiser, Raquel C. de Melo Minardi
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Machine learning-based drug discovery success depends on molecular representation. Yet traditional molecular fingerprints omit both the protein and pointers back to structural information that would enable better model interpretability. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2196412f3358bac2e7573c0b5e515e2f
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007749 (2020)
PLoS Computational Biology
PLoS Computational Biology
The renal outer medullary potassium (ROMK) channel is essential for potassium transport in the kidney, and its dysfunction is associated with a salt-wasting disorder known as Bartter syndrome. Despite its physiological significance, we lack a mechani