Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Luca Ponzone"'
Autor:
Luca Ponzone, Valentina Audrito, Claudia Landi, Enrico Moiso, Chiara Levra Levron, Sara Ferrua, Aurora Savino, Nicoletta Vitale, Massimiliano Gasparrini, Lidia Avalle, Lorenza Vantaggiato, Enxhi Shaba, Beatrice Tassone, Stefania Saoncella, Francesca Orso, Daniele Viavattene, Eleonora Marina, Irene Fiorilla, Giulia Burrone, Youssef Abili, Fiorella Altruda, Luca Bini, Silvia Deaglio, Paola Defilippi, Alessio Menga, Valeria Poli, Paolo Ettore Porporato, Paolo Provero, Nadia Raffaelli, Chiara Riganti, Daniela Taverna, Federica Cavallo, Enzo Calautti
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background The main drawback of BRAF/MEK inhibitors (BRAF/MEKi)-based targeted therapy in the management of BRAF-mutated cutaneous metastatic melanoma (MM) is the development of therapeutic resistance. We aimed to assess in this context the
Externí odkaz:
https://doaj.org/article/18874da7221f495c92ee85e23df7d535
Autor:
Roberto Ruiu, Chiara Cossu, Antonella Iacoviello, Laura Conti, Elisabetta Bolli, Luca Ponzone, Jolanda Magri, Alekya Rumandla, Enzo Calautti, Federica Cavallo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background The upregulation of antioxidant mechanisms is a common occurrence in cancer cells, as they strive to maintain balanced redox state and prevent oxidative damage. This includes the upregulation of the cystine/glutamate antiporter xC
Externí odkaz:
https://doaj.org/article/13f8c99deeec400184da758ebeb3e721
Publikováno v:
Cells, Vol 11, Iss 7, p 1130 (2022)
Keratinocyte stem cells play a fundamental role in homeostasis and repair of stratified epithelial tissues. Transplantation of cultured keratinocytes autografts provides a landmark example of successful cellular therapies by restoring durable integri
Externí odkaz:
https://doaj.org/article/1538baa0af3d4ae480dca9e3d7b77493
Publikováno v:
International Journal of Molecular Sciences. 23:9985
Malignant melanoma represents the most fatal skin cancer due to its aggressive behavior and high metastatic potential. The introduction of BRAF/MEK inhibitors and immune-checkpoint inhibitors (ICIs) in the clinic has dramatically improved patient sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15d54bdc5b213de706e9e7bfb1c6e36
https://doi.org/10.3390/ijms23179985
https://doi.org/10.3390/ijms23179985
Autor:
Barbara, Pergolizzi, Cristina, Panuzzo, M Shahzad, Ali, Marco, Lo Iacono, Chiara, Levra Levron, Luca, Ponzone, Marta, Prelli, Daniela, Cilloni, Enzo, Calautti, Salvatore, Bozzaro, Enrico, Bracco
Publikováno v:
Journal of cell science. 132(22)
Mammalian, or mechanistic, target of rapamycin complex 2 (mTORC2) regulates a variety of vital cellular processes, and its aberrant functioning is often associated with various diseases. Rictor is a peculiar and distinguishing mTORC2 component playin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbb036a991444d457a51b59be6db7de7
https://pubmed.ncbi.nlm.nih.gov/31653780
https://pubmed.ncbi.nlm.nih.gov/31653780
Autor:
Chiara Levra Levron, Luca Ponzone, M. Shahzad Ali, Salvatore Bozzaro, Daniela Cilloni, Enrico Bracco, Marta Prelli, Cristina Panuzzo, Enzo Calautti, Marco Lo Iacono, Barbara Pergolizzi
Publikováno v:
Journal of Cell Science.
Mammalian, or mechanistic, target of rapamycin complex 2 (mTORC2) regulates a variety of vital cellular processes, and its aberrant functioning is often associated with various diseases. Rictor is a peculiar and distinguishing mTORC2 component playin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e4a129ed956c90defdd732f59b3b46e
https://doi.org/10.1242/jcs.236505
https://doi.org/10.1242/jcs.236505