Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Luca Montemurro"'
Autor:
Silvia Lampis, Salvatore Raieli, Luca Montemurro, Damiano Bartolucci, Camilla Amadesi, Sonia Bortolotti, Silvia Angelucci, Anna Lisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Sabrina Valente, Matthias Fischer, Alberto Maria Martelli, Gianandrea Pasquinelli, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Neuroblastoma is a deadly childhood cancer, and MYCN-amplified neuroblastoma (MNA-NB) patients have the worst prognoses and are therapy-resistant. While retinoic acid (RA) is beneficial for some neuroblastoma patients, the cause o
Externí odkaz:
https://doaj.org/article/57da51d707e148518d41d12e01cff92a
Autor:
Salvatore Raieli, Daniele Di Renzo, Silvia Lampis, Camilla Amadesi, Luca Montemurro, Andrea Pession, Patrizia Hrelia, Matthias Fischer, Roberto Tonelli
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
A wide range of malignancies presents MYCN amplification (MNA) or dysregulation. MYCN is associated with poor prognosis and its over-expression leads to several dysregulations including metabolic reprogramming, mitochondria alteration, and cancer ste
Externí odkaz:
https://doaj.org/article/bad6d4a7273842c689a925b87929773e
Autor:
Roberto Tonelli, Patrizia Hrelia, Andrea Pession, Mirella Falconi, Gabriella Teti, Matthias Fischer, Lucia Cerisoli, Giammario Nieddu, Leonardo Venturelli, Anna Lisa Scardovi, Silvia Lampis, Camilla Amadesi, Damiano Bartolucci, Silvia Angelucci, Salvatore Raieli, Luca Montemurro
supplementary tables Supplementary Table 1: List of cell lines used in this study. Supplementary Table 2: List of the primers used in this study for quantitative Real Time PCR. Supplementary Table 3: Table showing the EC50 effect for BGA001 and BGA00
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f615f6c9a760623380d16bf3dcce87
https://doi.org/10.1158/0008-5472.22422393
https://doi.org/10.1158/0008-5472.22422393
Autor:
Roberto Tonelli, Patrizia Hrelia, Andrea Pession, Mirella Falconi, Gabriella Teti, Matthias Fischer, Lucia Cerisoli, Giammario Nieddu, Leonardo Venturelli, Anna Lisa Scardovi, Silvia Lampis, Camilla Amadesi, Damiano Bartolucci, Silvia Angelucci, Salvatore Raieli, Luca Montemurro
Approximately half of high-risk neuroblastoma is characterized by MYCN amplification. N-Myc promotes tumor progression by inducing cell growth and inhibiting differentiation. MYCN has also been shown to play an active role in mitochondrial metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9d544dabbf782acffc9a37313d6759
https://doi.org/10.1158/0008-5472.c.6511206
https://doi.org/10.1158/0008-5472.c.6511206
Autor:
Roberto Tonelli, Patrizia Hrelia, Andrea Pession, Mirella Falconi, Gabriella Teti, Matthias Fischer, Lucia Cerisoli, Giammario Nieddu, Leonardo Venturelli, Anna Lisa Scardovi, Silvia Lampis, Camilla Amadesi, Damiano Bartolucci, Silvia Angelucci, Salvatore Raieli, Luca Montemurro
Figure S1: BGA002 induces apoptosis Figure S2: BGA002 inhibits MYCN expression in a broad neuroblastoma cell-line panel Figure S3: BGA002 is a specific MYCN inhibitor Figure S4: Mitochondria structural alteration are MYCN specific inhibition. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7882380daa5fcd414c3d34a3fcbe743b
https://doi.org/10.1158/0008-5472.22422396.v1
https://doi.org/10.1158/0008-5472.22422396.v1
Autor:
Sonia Bortolotti, Silvia Angelucci, Luca Montemurro, Damiano Bartolucci, Salvatore Raieli, Silvia Lampis, Camilla Amadesi, Annalisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Francesca Chiarini, Gabriella Teti, Mirella Falconi, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 990
Volume 15
Issue 3
Pages: 990
Small-cell lung cancer (SCLC) is the most aggressive lung cancer type, and is associated with smoking, low survival rate due to high vascularization, metastasis and drug resistance. Alterations in MYC family members are biomarkers of poor prognosis f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6aa28f2fa1936adbf7088a18489a9e4
Autor:
Damiano Bartolucci, Luca Montemurro, Salvatore Raieli, Silvia Lampis, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Simple Summary Neuroblastoma is one of the most diffuse and the deadliest cancer in children. While many advances have been made in the last few decades to improve patients' outcome, high-risk neuroblastoma (HR-NB) still shows a very aggressive patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e00b13c90a049f97cd517d10aab28ec
https://hdl.handle.net/11585/900170
https://hdl.handle.net/11585/900170
Autor:
Andrea Pession, Silvia Lampis, Daniele Di Renzo, Matthias Fischer, Salvatore Raieli, Patrizia Hrelia, Roberto Tonelli, Camilla Amadesi, Luca Montemurro
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
A wide range of malignancies presents MYCN amplification (MNA) or dysregulation. MYCN is associated with poor prognosis and its over-expression leads to several dysregulations including metabolic reprogramming, mitochondria alteration, and cancer ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db6474a0b74314d33a2786fb2f97d4e
https://doi.org/10.3389/fonc.2021.625207
https://doi.org/10.3389/fonc.2021.625207
Autor:
Tiziano Schillaci, Francesco Zanetti, Keren Shabtai, Luca Montemurro, Dina Katsir, Antonia Simone, Marco Castronuovo
Publikováno v:
International Conference on Space Optics — ICSO 2018.
In the context of ESA’s Cosmic Vision 2015-2025 scientific program, Solar Orbiter (SolO) represents the first M-class mission, currently under implementation for a launch planned in October 2018. One of the SolO solar remote-sensing instruments is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8248fc8ab8898a315f95116e057a03bb
https://doi.org/10.1117/12.2536097
https://doi.org/10.1117/12.2536097
Autor:
Anna Lisa Scardovi, Giammario Nieddu, Matthias Fischer, Camilla Amadesi, Roberto Tonelli, Lucia Cerisoli, Andrea Pession, Gabriella Teti, Luca Montemurro, Salvatore Raieli, Patrizia Hrelia, Leonardo Venturelli, Silvia Angelucci, Silvia Lampis, Mirella Falconi, Damiano Bartolucci
Approximately half of high-risk neuroblastoma is characterized by MYCN amplification. N-Myc promotes tumor progression by inducing cell growth and inhibiting differentiation. MYCN has also been shown to play an active role in mitochondrial metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec26d9b798908926b20c5c84d5875ce
http://hdl.handle.net/11585/714781
http://hdl.handle.net/11585/714781