Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Luca Mologni"'
Autor:
Matteo Villa, Federica Malighetti, Elisa Sala, Geeta G. Sharma, Giulia Arosio, Maria Gemelli, Chiara Manfroni, Diletta Fontana, Nicoletta Cordani, Raffaella Meneveri, Alfonso Zambon, Rocco Piazza, Fabio Pagni, Diego Cortinovis, Luca Mologni
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract ALK and ROS1 fusions are effectively targeted by tyrosine kinase inhibitors (TKIs), however patients inevitably relapse after an initial response, often due to kinase domain mutations. We investigated circulating DNA from TKI-relapsed NSCLC
Externí odkaz:
https://doaj.org/article/99f488c2e4a640108d5e08ac02e23058
Autor:
Francesca Foschi, Annachiara Tinivella, Valentina Crippa, Luca Pinzi, Luca Mologni, Daniele Passarella, Giulio Rastelli
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 239-245 (2023)
AbstractEGFR is a protein kinase whose aberrant activity is frequently involved in the development of non-small lung cancer (NSCLC) drug resistant forms. The allosteric inhibition of this enzyme is currently one among the most attractive approaches t
Externí odkaz:
https://doaj.org/article/25d2bf8ec18e40be90168dfa859cc71c
Autor:
Diletta Fontana, Ilaria Crespiatico, Valentina Crippa, Federica Malighetti, Matteo Villa, Fabrizio Angaroni, Luca De Sano, Andrea Aroldi, Marco Antoniotti, Giulio Caravagna, Rocco Piazza, Alex Graudenzi, Luca Mologni, Daniele Ramazzotti
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Recurring sequences of genomic alterations occurring across patients can highlight repeated evolutionary processes with significant implications for predicting cancer progression. Leveraging the ever-increasing availability of cancer omics d
Externí odkaz:
https://doaj.org/article/2c8ebc0ac2384c04920b0f140fda5e6f
Autor:
Mattia Zaghi, Federica Banfi, Luca Massimino, Monica Volpin, Edoardo Bellini, Simone Brusco, Ivan Merelli, Cristiana Barone, Michela Bruni, Linda Bossini, Luigi Antonio Lamparelli, Laura Pintado, Deborah D’Aliberti, Silvia Spinelli, Luca Mologni, Gaia Colasante, Federica Ungaro, Jean-Michel Cioni, Emanuele Azzoni, Rocco Piazza, Eugenio Montini, Vania Broccoli, Alessandro Sessa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Within the chromatin, distal elements interact with promoters to regulate specific transcriptional programs. Histone acetylation, interfering with the net charges of the nucleosomes, is a key player in this regulation. Here, we report that t
Externí odkaz:
https://doaj.org/article/dfd430e45aab49efbf05d9df651f99c5
Autor:
Matteo Villa, Federica Malighetti, Mario Mauri, Geeta G Sharma, Cosimo Lobello, Hugo Larose, Alessandra Pirola, Silvia Bombelli, Nicoletta Cordani, Luca Massimino, Šárka Pospíšilová, Suzanne D. Turner, Giorgio Inghirami, Lisa Pagani, Lucrezia Criscuolo, Fulvio Magni, Roberto Perego, Fabio Pagni, Rocco Piazza, Roberto Chiarle, Carlo Gambacorti-Passerini, Luca Mologni
Publikováno v:
HemaSphere, Vol 7, p e4206968 (2023)
Externí odkaz:
https://doaj.org/article/57ce5fe60c654f75b7e0fbc49a80ff02
Autor:
Federica Malighetti, Giulia Arosio, Chiara Manfroni, Mario Mauri, Matteo Villa, Beatrice Manghisi, Elena Inzoli, Giovanni Rindone, Giovanni P. M. Zambrotta, Ivan Civettini, Veronica Guglielmana, Daniele Ramazzotti, Giovanni Giudici, Silvia Bombelli, Roberto Perego, Rocco Piazza, Luca Mologni, Carlo Gambacorti-Passerini
Publikováno v:
HemaSphere, Vol 7, Iss 3, p e852 (2023)
Externí odkaz:
https://doaj.org/article/0bb1561356c44b59900289c5a5a83bde
Autor:
Nicoletta Cordani, Luca Mologni, Rocco Piazza, Pietro Tettamanti, Viola Cogliati, Mario Mauri, Matteo Villa, Federica Malighetti, Camillo Di Bella, Marta Jaconi, Maria Grazia Cerrito, Guido Cavaletti, Marialuisa Lavitrano, Marina Elena Cazzaniga
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16294 (2023)
Cyclin-dependent kinase (CDK) 4/6 inhibitors have significantly improved progression-free survival in hormone-receptor-positive (HR+), human-epidermal-growth-factor-receptor-type-2-negative (HER2−) metastatic luminal breast cancer (mLBC). Several s
Externí odkaz:
https://doaj.org/article/cf9d976d484444958bb6745f0655ce80
Autor:
Federica Banfi, Alicia Rubio, Mattia Zaghi, Luca Massimino, Giulia Fagnocchi, Edoardo Bellini, Mirko Luoni, Cinzia Cancellieri, Anna Bagliani, Chiara Di Resta, Camilla Maffezzini, Angelo Ianielli, Maurizio Ferrari, Rocco Piazza, Luca Mologni, Vania Broccoli, Alessandro Sessa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Schinzel-Giedion syndrome (SGS) is a fatal developmental syndrome characterized by severe intellectual and physical deficits due, at least in part, to early neurodegeneration. Here the authors introduce a human SGS model that displays disease-relevan
Externí odkaz:
https://doaj.org/article/9f82d3e4675e4ed291494e6ac2e0dfe7
Autor:
Nicoletta Cordani, Daniela Lisini, Valentina Coccè, Giuseppe Paglia, Ramona Meanti, Maria Grazia Cerrito, Pietro Tettamanti, Luca Bonaffini, Francesca Paino, Giulio Alessandri, Angela Marcianti, Aldo Giannì, Chiara Villa, Mario Mauri, Luca Mologni, Antonio Torsello, Augusto Pessina, Marina Elena Cazzaniga
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5864 (2023)
Triple-negative breast cancer (TNBC) is a very aggressive disease even in its early stages and is characterized by a severe prognosis. Neoadjuvant chemotherapy is one of the milestones of treatment, and paclitaxel (PTX) is among the most active drugs
Externí odkaz:
https://doaj.org/article/e11a3b513a2041e0bac041e02afa0900
Autor:
Luca Mologni, Sébastien Tardy, Alfonso Zambon, Alexandre Orsato, Cédric Schneider, William H. Bisson, Monica Ceccon, Michela Viltadi, David Goyard, Pierre Garcia, Joseph D’Attoma, Sara Pannilunghi, Vito Vece, Jerome Bertho, David Gueyrard, Peter Goekjian, Leonardo Scapozza, Carlo Gambacorti-Passerini
Publikováno v:
ACS Omega, Vol 7, Iss 25, Pp 22059-22060 (2022)
Externí odkaz:
https://doaj.org/article/06412c463a324452867b30b2e8ae1c45