Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luca Michetti"'
Autor:
Hagar F. Moussa, Daniel Bsteh, Ramesh Yelagandula, Carina Pribitzer, Karin Stecher, Katarina Bartalska, Luca Michetti, Jingkui Wang, Jorge A. Zepeda-Martinez, Ulrich Elling, Jacob I. Stuckey, Lindsey I. James, Stephen V. Frye, Oliver Bell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to promote gene silencing. Here the authors use reversible tethering of Polycomb proteins to ectopic sites in mouse ESCs and find that canonical but not variant PRC
Externí odkaz:
https://doaj.org/article/c3dcbf63ea4b486cbed795c1f715237f
Autor:
Ramesh Yelagandula, Karin Stecher, Maria Novatchkova, Luca Michetti, Georg Michlits, Jingkui Wang, Pablo Hofbauer, Gintautas Vainorius, Carina Pribitzer, Luke Isbel, Sasha Mendjan, Dirk Schübeler, Ulrich Elling, Julius Brennecke, Oliver Bell
Publikováno v:
Nat Cell Biol
ZNF462 haploinsufficiency is linked to Weiss-Kruszka syndrome, a genetic disorder characterized by neurodevelopmental defects, including autism. Though conserved in vertebrates and essential for embryonic development, the molecular functions of ZNF46
Autor:
Jorge A. Zepeda-Martinez, Luca Michetti, Lindsey I. James, Daniel Bsteh, Karin Stecher, Ulrich Elling, Katarina Bartalska, Stephen V. Frye, Hagar F. Moussa, Jingkui Wang, Jacob I. Stuckey, Oliver Bell, Ramesh Yelagandula, Carina Pribitzer
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to enforce gene silencing, but how transcriptional repression is p