Effects of ebselen addition on emotional processing and brain neurochemistry in depressed patients unresponsive to antidepressant medication

Autor: Fitri Fareez Ramli, Nisha Singh, Uzay E. Emir, Luca M. Villa, Shona Waters, Catherine J. Harmer, Philip J. Cowen, Beata R. Godlewska

Publikováno v: Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)

Abstract Lithium is an effective augmenting agent for depressed patients with inadequate response to standard antidepressant therapy, but numerous adverse effects limit its use. We previously reported that a lithium-mimetic agent, ebselen, promoted a

Externí odkaz: https://doaj.org/article/9ac15562ad8942dda42f51e7313e6289

Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders

Autor: Lejla Colic, Luca M. Villa, Maria R. Dauvermann, Laura S. vanVelzen, Anjali Sankar, Danielle A. Goldman, Priyanka Panchal, Jihoon A. Kim, Susan Quatrano, Linda Spencer, R. Todd Constable, John Suckling, Ian M. Goodyer, Lianne Schmaal, Anne‐Laura vanHarmelen, Hilary P. Blumberg

Publikováno v: JCPP Advances, Vol 2, Iss 4, Pp n/a-n/a (2022)

Abstract Background To reduce suicide in females with mood disorders, it is critical to understand brain substrates underlying their vulnerability to future suicidal ideation and behaviors (SIBs) in adolescence and young adulthood. In an internationa

Externí odkaz: https://doaj.org/article/673701da66e146e4bdf2570752ce38e9

Bipolar I and bipolar II subtypes in older age: Results from the Global Aging and Geriatric Experiments in Bipolar Disorder ( GAGE‐BD ) project

Autor: Alexandra J. M. Beunders, Federica Klaus, Almar A. L. Kok, Sigfried N. T. M. Schouws, Ralph W. Kupka, Hilary P. Blumberg, Farren Briggs, Lisa T. Eyler, Brent P. Forester, Orestes V. Forlenza, Ariel Gildengers, Esther Jimenez, Benoit H. Mulsant, Regan E. Patrick, Soham Rej, Martha Sajatovic, Kaylee Sarna, Ashley Sutherland, Joy Yala, Eduard Vieta, Luca M. Villa, Nicole C. M. Korten, Annemieke Dols

Publikováno v: Bipolar Disorders, 25(1), 43-55. Blackwell Munksgaard
Beunders, A J M, Klaus, F, Kok, A A L, Schouws, S N T M, Kupka, R W, Blumberg, H P, Briggs, F, Eyler, L T, Forester, B P, Forlenza, O V, Gildengers, A, Jimenez, E, Mulsant, B H, Patrick, R E, Rej, S, Sajatovic, M, Sarna, K, Sutherland, A, Yala, J, Vieta, E, Villa, L M, Korten, N C M & Dols, A 2023, ' Bipolar I and bipolar II subtypes in older age : Results from the Global Aging and Geriatric Experiments in Bipolar Disorder (GAGE-BD) project ', Bipolar Disorders, vol. 25, no. 1, pp. 43-55 . https://doi.org/10.1111/bdi.13271
Bipolar disorders, vol 25, iss 1

ObjectivesThe distinction between bipolar I disorder (BD-I) and bipolar II disorder (BD-II) has been a topic of long-lasting debate. This study examined differences between BD-I and BD-II in a large, global sample of OABD, focusing on general functio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b21a48ef89fbb1dba073f74b0edfc8
https://doi.org/10.1111/bdi.13271

Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD): Recommendations from the GAGE-BD group

Autor: Paola Lavin, Soham Rej, Andrew T. Olagunju, Antonio L. Teixeira, Annemieke Dols, Martin Alda, Osvaldo P. Almeida, Kursat Altinbas, Vicent Balanzá‐Martínez, Izabela G. Barbosa, Hilary P. Blumberg, Farren Briggs, Cynthia Calkin, Kristin Cassidy, Brent P. Forester, Orestes V. Forlenza, Tomas Hajek, Barthomeus C. M. Haarman, Esther Jimenez, Beny Lafer, Benoit Mulsant, Stephen O. Oluwaniyi, Regan Patrick, Joaquim Radua, Sigfried Schouws, Harmehr Sekhon, Christian Simhandl, Jair C. Soares, Shang‐Ying Tsai, Eduard Vieta, Luca M. Villa, Martha Sajatovic, Lisa T. Eyler

Publikováno v: Bipolar Disorders. Blackwell Munksgaard
Lavin, P, Rej, S, Olagunju, A T, Teixeira, A L, Dols, A, Alda, M, Almeida, O P, Altinbas, K, Balanzá-Martínez, V, Barbosa, I G, Blumberg, H P, Briggs, F, Calkin, C, Cassidy, K, Forester, B P, Forlenza, O V, Hajek, T, Haarman, B C M, Jimenez, E, Lafer, B, Mulsant, B, Oluwaniyi, S O, Patrick, R, Radua, J, Schouws, S, Sekhon, H, Simhandl, C, Soares, J C, Tsai, S-Y, Vieta, E, Villa, L M, Sajatovic, M & Eyler, L T 2023, ' Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD) : Recommendations from the GAGE-BD group ', Bipolar Disorders . https://doi.org/10.1111/bdi.13312

Background: By 2030, over 50% of individuals living with bipolar disorder (BD) are expected to be aged ≥50 years. However, older age bipolar disorder (OABD) remains understudied. There are limited large-scale prospectively collected data organized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b711f498197c5f7319a9e3f1cd9598bf
https://research.vumc.nl/en/publications/d06f22f6-3970-4e58-845c-2fa817718715

Neuroimaging Studies of Brain Structure in Older Adults with Bipolar Disorder: A Review

Autor: Niroop, Rajashekar, Hilary P, Blumberg, Luca M, Villa

Publikováno v: Journal of psychiatry and brain science. 7(4)

Bipolar disorder (BD) is a common mood disorder that can have severe consequences during later life, including suffering and impairment due to mood and cognitive symptoms, elevated risk for dementia and an especially high risk for suicide. Greater un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24d1467d510789b1e1810838545ee35b
https://pubmed.ncbi.nlm.nih.gov/36092855