Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luca Licenziato"'
Autor:
Antonella Fanelli, Luca Licenziato, Eugenio Mazzone, Sara Divari, Andrea Rinaldi, Michele Marino, Ilaria Maga, Francesco Bertoni, Laura Marconato, Luca Aresu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract We present here the K9 lymphoma assay, a novel 31-gene targeted next-generation sequencing panel designed for genomic profiling of canine lymphoid neoplasms. Addressing the growing demand for advanced diagnostics in veterinary oncology, this
Externí odkaz:
https://doaj.org/article/1f64444aa12346889b3e8a8991c4da6e
Autor:
Greta Foiani, Luca Licenziato, Laura Marconato, Antonella Fanelli, Erica Melchiotti, Claudia Zanardello, Luca Aresu, Marta Vascellari
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-9 (2024)
TP53 mutations are associated with short survival and poor treatment response in canine diffuse large B-cell lymphoma (cDLBCL). The expression of TP53 by RNAscope® in situ hybridization and p53 by immunohistochemistry (IHC) was investigated in 37 fo
Externí odkaz:
https://doaj.org/article/cf30fb8de5df4bb5baadbef7602420c8
Autor:
Sara Meazzi, Valeria Martini, Laura Marconato, Marina Aralla, Luca Licenziato, Matteo Olimpo, Paola Roccabianca, Silvia Sabattini, Alessandra Ubiali, Riccardo Zaccone, Luca Aresu
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-7 (2024)
Splenic nodular lesions in dogs can be either benign or malignant. They might be discovered incidentally or, in case of rupture, they may lead to hemoabdomen. Nevertheless, splenectomy followed by histopathology is essential for diagnosis and to prev
Externí odkaz:
https://doaj.org/article/22effe9df79248d0b05ae9aeaa4dc06f
Autor:
Luca Licenziato, Eugenio Mazzone, Chiara Tarantelli, Paolo Accornero, Andrea Rinaldi, Sara Divari, Wilfred Leung, Suzin Webb, Raffaella De Maria, Luca Aresu
Publikováno v:
Animals, Vol 14, Iss 10, p 1466 (2024)
B-cell lymphomas (BCL) is the most frequent hematological cancer in dogs. Treatment typically consists of chemotherapy, with CHOP-based protocols. However, outcome remains generally poor, urging the exploration of new therapeutic strategies with a ta
Externí odkaz:
https://doaj.org/article/83ecd15099da4c5db884a7dfda4a61ec
Autor:
Antonella Fanelli, Laura Marconato, Luca Licenziato, Lucia Minoli, Nicole Rouquet, Luca Aresu
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Diffuse large B-cell lymphoma (DLBCL) represents one of the most frequent and deadliest neoplasia in dogs worldwide and is characterized by a remarkable degree of clinical heterogeneity, with poor chances to anticipate the outcome. Even if in the las
Externí odkaz:
https://doaj.org/article/a47d50de38f146b3a5dfa9981cedf39a
Autor:
Gennaro Altamura, Barbara degli Uberti, Giorgio Galiero, Giovanna De Luca, Karen Power, Luca Licenziato, Paola Maiolino, Giuseppe Borzacchiello
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2021)
Expression of telomerase reverse transcriptase (TERT) and telomerase activity (TA) is a main feature of cancer, contributing to cell immortalization by causing telomeres dysfunction. BIBR1532 is a potent telomerase inhibitor that showed potential ant
Externí odkaz:
https://doaj.org/article/00fa258a6c5d49b4aa0a98ed59cacd08
Autor:
Federica Riva, Joel Filipe, Antonella Fanelli, Laura Marconato, Alessia Inglesi, Eugenio Scanziani, Sabina Soldati, Luca Licenziato, Stefano Comazzi, Lucia Minoli, Luca Aresu
Publikováno v:
Veterinary Sciences, Vol 9, Iss 5, p 209 (2022)
Diffuse large B-cell lymphoma (DLBCL) is the most common hematological malignancy in humans and dogs. Several studies disclosed some similarities between the two species, including the constitutive activation of the NF-κB pathway as a fundamental un
Externí odkaz:
https://doaj.org/article/5c20a3b66c9e4df5b17cf0286c69402d
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Telomerase activity contributes to cell immortalization by avoiding telomere shortening at each cell division; indeed, its catalytic subunit telomerase reverse transcriptase (TERT) is overexpressed in many tumors, including human oral squamous cell c
Externí odkaz:
https://doaj.org/article/74aebac6f4e64ae3ae75cc131f3a4736
Autor:
Luca Aresu, Laura Marconato, Valeria Martini, Antonella Fanelli, Luca Licenziato, Greta Foiani, Erica Melchiotti, Arturo Nicoletti, Marta Vascellari
Publikováno v:
Veterinary Sciences, Vol 8, Iss 7, p 120 (2021)
Immune checkpoints are a set of molecules dysregulated in several human and canine cancers and aberrations of the PD-1/PD-L1 axis are often correlated with a worse prognosis. To gain an insight into the role of immune checkpoints in canine diffuse la
Externí odkaz:
https://doaj.org/article/5c501d6870364c0fab252dd7748bd44a
Autor:
Cecilia Gola, Luca Licenziato, Paolo Accornero, Selina Iussich, Emanuela Morello, Paolo Buracco, Paola Modesto, Luca Aresu, Raffaella De Maria
Publikováno v:
Veterinary and Comparative Oncology. 20:890-900
Osteosarcoma is the most common primary malignant bone tumour in dogs, characterized by a locally aggressive and highly metastatic behaviour. Despite the current standards of care, most dogs succumb to the disease, indicating the need for novel treat