Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Luca Galgano"'
Autor:
Claudio Casali, Luca Galgano, Lorena Zannino, Stella Siciliani, Margherita Cavallo, Giuliano Mazzini, Marco Biggiogera
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 1, Pp 151373- (2024)
Cells are continuously exposed to various sources of insults, among which temperature variations are extremely common. Epigenetic mechanisms, critical players in gene expression regulation, undergo alterations due to these stressors, potentially lead
Externí odkaz:
https://doaj.org/article/681f3252c18c4e15a9184aa3984b740d
Autor:
Mauro Vismara, Marcello Manfredi, Marta Zarà, Silvia Maria Grazia Trivigno, Luca Galgano, Silvia Stella Barbieri, Ilaria Canobbio, Mauro Torti, Gianni Francesco Guidetti
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract During hemostasis, thrombosis, and inflammation, activated blood platelets release extracellular vesicles (PEVs) that represent biological mediators of physiological and pathological processes. We have recently demonstrated that the activati
Externí odkaz:
https://doaj.org/article/82644e19bbd7400785eb6766b19484f4
Autor:
Stefania Momi, Jessica Canino, Mauro Vismara, Luca Galgano, Emanuela Falcinelli, Giuseppe Guglielmini, Giulia Ciarrocca Taranta, Gianni Francesco Guidetti, Paolo Gresele, Mauro Torti, Ilaria Canobbio
Publikováno v:
Haematologica, Vol 107, Iss 6 (2022)
Deep vein thrombosis results from the cooperative action of leukocytes, platelets, and endothelial cells. The proline-rich tyrosine kinase Pyk2 regulates platelet activation and supports arterial thrombosis. In this study, we combined pharmacological
Externí odkaz:
https://doaj.org/article/00d6af882ac84c3e9f0e89b83fa48a18
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 153 (2022)
Cell genome integrity is continuously threatened by various sources, both endogenous and exogenous. Oxidative stress causes a multitude of damages, severely affecting cell viability, fidelity of genetic information inheritance, and determining profou
Externí odkaz:
https://doaj.org/article/5d8de7a2174b4707a67b70e8f2b1a70f
Autor:
Mauro Vismara, Sharon Negri, Francesca Scolari, Valentina Brunetti, Silvia Maria Grazia Trivigno, Pawan Faris, Luca Galgano, Teresa Soda, Roberto Berra-Romani, Ilaria Canobbio, Mauro Torti, Gianni Francesco Guidetti, Francesco Moccia
Publikováno v:
Cells, Vol 11, Iss 19, p 3120 (2022)
Background: Platelets can support cancer progression via the release of microparticles and microvesicles that enhance the migratory behaviour of recipient cancer cells. We recently showed that platelet-derived extracellular vesicles (PEVs) stimulate
Externí odkaz:
https://doaj.org/article/b0fc36d9bebc4dddbab9826e93ddd4c8
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10900 (2022)
Circulating platelets are responsible for hemostasis and thrombosis but are also primary sensors of pathogens and are involved in innate immunity, inflammation, and sepsis. Sepsis is commonly caused by an exaggerated immune response to bacterial, vir
Externí odkaz:
https://doaj.org/article/75fed985f90643ed8cbfc149ba3a223a
Autor:
Luca Galgano, Ilaria Canobbio, Jessica Canino, Mauro Vismara, Gianni Francesco Guidetti, Giampaolo Minetti, Mauro Torti
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1867(10)
Neutrophils are first responders in infection and inflammation. They are able to roll, adhere and transmigrate through the endothelium to reach the site of infection, where they fight pathogens through secretion of granule contents, production of rea