Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Luca G Wanderlingh"'
Autor:
Chiara Soldati, Irene Lopez‐Fabuel, Luca G Wanderlingh, Marina Garcia‐Macia, Jlenia Monfregola, Alessandra Esposito, Gennaro Napolitano, Marta Guevara‐Ferrer, Anna Scotto Rosato, Einar K Krogsaeter, Dominik Paquet, Christian M Grimm, Sandro Montefusco, Thomas Braulke, Stephan Storch, Sara E Mole, Maria A De Matteis, Andrea Ballabio, Julio L Sampaio, Tristan McKay, Ludger Johannes, Juan P Bolaños, Diego L Medina
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-19 (2021)
Abstract Batten diseases (BDs) are a group of lysosomal storage disorders characterized by seizure, visual loss, and cognitive and motor deterioration. We discovered increased levels of globotriaosylceramide (Gb3) in cellular and murine models of CLN
Externí odkaz:
https://doaj.org/article/d6c8d9dd375c49b29d6deee58e6d431f
Autor:
Gabriella Minchiotti, Eduardo J. Patriarca, Giorgio Scita, Dario De Cesare, Maria R. Matarazzo, Laura Casalino, Francesca Varrone, Agnese Migliaccio, Miriam Gagliardi, Luca G. Wanderlingh, Andrea Palamidessi, Federica Cermola, Cristina D'Aniello
Supplementary data include Figure S1(Structural determinants of ESC inhibitors), Figure S2 (Validation and functional characterization of esMTi), Figure S3 (Generation and characterization of P4H deficient ESCs), Figure S4 (Budesonide activity on A54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0fa1a7287ce2e8d63bb834d252f759
https://doi.org/10.1158/0008-5472.22421478.v1
https://doi.org/10.1158/0008-5472.22421478.v1
Autor:
Gabriella Minchiotti, Eduardo J. Patriarca, Giorgio Scita, Dario De Cesare, Maria R. Matarazzo, Laura Casalino, Francesca Varrone, Agnese Migliaccio, Miriam Gagliardi, Luca G. Wanderlingh, Andrea Palamidessi, Federica Cermola, Cristina D'Aniello
Collagen prolyl hydroxylation (CPH), which is catalyzed by prolyl 4-hydroxylase (P4H), is the most prevalent posttranslational modification in humans and requires vitamin C (VitC). Here, we demonstrate that CPH acts as an epigenetic modulator of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb7ca65bd0c205e30591d523fb258a
https://doi.org/10.1158/0008-5472.c.6510942
https://doi.org/10.1158/0008-5472.c.6510942
Autor:
Antonella Di Costanzo, Francesco Scalabrì, Gennaro Andolfi, Sergio Altamura, Luca G Wanderlingh, Gabriella Minchiotti, Eduardo J. Patriarca, Elvira Ragozzino, Mariarita Brancaccio, Francesca Varrone, Vincenzo Summa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Dystrophies are characterized by progressive skeletal muscle degeneration and weakness as consequence of their molecular abnormalities. Thus, new drugs for restoring skeletal muscle deterioration are critically needed. To identify new and alternative
Autor:
Francesco Scalabrì, Francesca Varrone, Antonella Di Costanzo, Gabriella Minchiotti, Sergio Altamura, Elvira Ragozzino, Vincenzo Summa, Luca G Wanderlingh, Eduardo J. Patriarca, Mariarita Brancaccio, Gennaro Andolfi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Agnese Migliaccio, Cristina D'Aniello, Eduardo J. Patriarca, Dario De Cesare, Andrea Palamidessi, Laura Casalino, Maria R. Matarazzo, Federica Cermola, Miriam Gagliardi, Giorgio Scita, Francesca Varrone, Gabriella Minchiotti, Luca G Wanderlingh
Publikováno v:
Cancer research (Chic. Ill.) 79 (2019): 3235–3250. doi:10.1158/0008-5472.CAN-18-2070
info:cnr-pdr/source/autori:D'Aniello, Cristina; Cermola, Federica; Palamidessi, Andrea; Wanderlingh, Luca G.; Gagliardi, Miriam; Migliaccio, Agnese; Varrone, Francesca; Casalino, Laura; Matarazzo, Maria R.; De Cesare, Dario; Scita, Giorgio; Patriarca, Eduardo J.; Minchiotti, Gabriella/titolo:Collagen Prolyl Hydroxylation-Dependent Metabolic Perturbation Governs Epigenetic Remodeling and Mesenchymal Transition in Pluripotent and Cancer Cells/doi:10.1158%2F0008-5472.CAN-18-2070/rivista:Cancer research (Chic. Ill.)/anno:2019/pagina_da:3235/pagina_a:3250/intervallo_pagine:3235–3250/volume:79
info:cnr-pdr/source/autori:D'Aniello, Cristina; Cermola, Federica; Palamidessi, Andrea; Wanderlingh, Luca G.; Gagliardi, Miriam; Migliaccio, Agnese; Varrone, Francesca; Casalino, Laura; Matarazzo, Maria R.; De Cesare, Dario; Scita, Giorgio; Patriarca, Eduardo J.; Minchiotti, Gabriella/titolo:Collagen Prolyl Hydroxylation-Dependent Metabolic Perturbation Governs Epigenetic Remodeling and Mesenchymal Transition in Pluripotent and Cancer Cells/doi:10.1158%2F0008-5472.CAN-18-2070/rivista:Cancer research (Chic. Ill.)/anno:2019/pagina_da:3235/pagina_a:3250/intervallo_pagine:3235–3250/volume:79
Collagen prolyl hydroxylation (CPH), which is catalyzed by prolyl 4-hydroxylase (P4H), is the most prevalent posttranslational modification in humans and requires vitamin C (VitC). Here, we demonstrate that CPH acts as an epigenetic modulator of cell