Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Luca Cartegni"'
Autor:
Wenjian Kang, Shan Liu, Jin Xu, Anna Abrimian, Ayma F. Malik, Raymond Chien, Adejuyigbe Adaralegbe, Akwasi Amponsah, Luca Cartegni, John Pintar, Ying-Xian Pan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3010 (2022)
The mu opioid receptor has a distinct place in the opioid receptor family, since it mediates the actions of most opioids used clinically (e.g., morphine and fentanyl), as well as drugs of abuse (e.g., heroin). The single-copy mu opioid receptor gene,
Externí odkaz:
https://doaj.org/article/e8c5779cc1934974b2d12a3e74853a46
Autor:
Shan Liu, Wen-Jia Kang, Anna Abrimian, Jin Xu, Luca Cartegni, Susruta Majumdar, Patrick Hesketh, Alex Bekker, Ying-Xian Pan
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1525 (2021)
Most opioid analgesics used clinically, including morphine and fentanyl, as well as the recreational drug heroin, act primarily through the mu opioid receptor, a class A Rhodopsin-like G protein-coupled receptor (GPCR). The single-copy mu opioid rece
Externí odkaz:
https://doaj.org/article/8fc2fb547d2a4b66bb43e4e59c47db7e
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e49721 (2013)
ERG, a member of the ETS transcription factor family, is frequently overexpressed in prostate cancer as a result of its fusion to the androgen-responsive Tmprss2 gene. Different genomic rearrangements and alternative splicing events around the juncti
Externí odkaz:
https://doaj.org/article/49127794294440de94b66a03f9d21ade
Autor:
Lee Spraggon, Luca Cartegni
Publikováno v:
International Journal of Cell Biology, Vol 2013 (2013)
Pre-mRNA splicing and polyadenylation are critical steps in the maturation of eukaryotic mRNA. U1 snRNP is an essential component of the splicing machinery and participates in splice-site selection and spliceosome assembly by base-pairing to the 5′
Externí odkaz:
https://doaj.org/article/91b2313e2a8743bea166d4bfc99462db
Autor:
Laura Breda, Carla Casu, Sara Gardenghi, Nicoletta Bianchi, Luca Cartegni, Mohandas Narla, Karina Yazdanbakhsh, Marco Musso, Deepa Manwani, Jane Little, Lawrence B Gardner, Dorothy A Kleinert, Eugenia Prus, Eitan Fibach, Robert W Grady, Patricia J Giardina, Roberto Gambari, Stefano Rivella
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32345 (2012)
Preclinical and clinical studies demonstrate the feasibility of treating β-thalassemia and Sickle Cell Disease (SCD) by lentiviral-mediated transfer of the human β-globin gene. However, previous studies have not addressed whether the ability of len
Externí odkaz:
https://doaj.org/article/472254d68557495b9619e90809e22289
Autor:
Wen Jia Kang, Patrick Hesketh, Luca Cartegni, Ying Xian Pan, Alex Bekker, Susruta Majumdar, Shan Liu, Jin Xu, Anna Abrimian
Publikováno v:
Biomolecules, Vol 11, Iss 1525, p 1525 (2021)
Most opioid analgesics used clinically, including morphine and fentanyl, as well as the recreational drug heroin, act primarily through the mu opioid receptor, a class A Rhodopsin-like G protein-coupled receptor (GPCR). The single-copy mu opioid rece
Autor:
Jeong Eun, Park, Luca, Cartegni
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1648
Regulation of alternative splicing can be harnessed by antisense-based compounds to control gene expression. Antisense-mediated splicing interference has become a valuable molecular tool to modulate endogenous alternative splicing patterns, to correc
Autor:
Luca Cartegni, Jeong Eun Park
Publikováno v:
Methods in Molecular Biology ISBN: 9781493972036
Regulation of alternative splicing can be harnessed by antisense-based compounds to control gene expression. Antisense-mediated splicing interference has become a valuable molecular tool to modulate endogenous alternative splicing patterns, to correc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7f4e2aa4ffac25ecada07779884308
https://doi.org/10.1007/978-1-4939-7204-3_4
https://doi.org/10.1007/978-1-4939-7204-3_4
Autor:
Mingming Xu, Luca Cartegni, Robert J. Klein, Wenhua Zhou, Zhigang Lu, Gavril W. Pasternak, Shixiong Ding, Jin Xu, Xiaohu Xie, Yi Deng, Ling Pan, Ying-Xian Pan, Huifen Liu, Yasmin L. Hurd
Publikováno v:
Journal of Neuroscience. 34:11048-11066
Single nucleotide polymorphisms (SNPs) in the OPRM1 gene have been associated with vulnerability to opioid dependence. The current study identifies an association of an intronic SNP (rs9479757) with the severity of heroin addiction among Han-Chinese
Autor:
Luca Cartegni, Prasad Subramaniam
Publikováno v:
Cancer Research. 79:2642-2642
The signal transducer and activator of transcription 3 (STAT3) is linked to multiple cancers, including breast and lung adenocarcinomas, where it is known to activate multiple oncogenic pathways and serve as a bypass mechanism in drug resistance. For