Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Luca Cardelli"'
Autor:
Rosa D. Hernansaiz-Ballesteros, Csenge Földi, Luca Cardelli, László G. Nagy, Attila Csikász-Nagy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In eukaryotes the entry into mitosis is initiated by activation of cyclin-dependent kinases (CDKs), which in turn activate a large number of protein kinases to induce all mitotic processes. The general view is that kinases are active in mito
Externí odkaz:
https://doaj.org/article/3d5157b4495846c49c1da2771ff85aae
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103462- (2021)
Summary: Cells can sense temporal changes of molecular signals, allowing them to predict environmental variations and modulate their behavior. This paper elucidates biomolecular mechanisms of time derivative computation, facilitating the design of re
Externí odkaz:
https://doaj.org/article/1ab9b7dc0d2749989dea1fd60c4b78dc
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 3, p e1007651 (2020)
Biological systems are made up of components that change their actions (and interactions) over time and coordinate with other components nearby. Together with a large state space, the complexity of this behaviour can make it difficult to create conci
Externí odkaz:
https://doaj.org/article/63541f81f1084f159416f9cc450ce280
Publikováno v:
Computation, Vol 9, Iss 10, p 107 (2021)
Automation is becoming ubiquitous in all laboratory activities, moving towards precisely defined and codified laboratory protocols. However, the integration between laboratory protocols and mathematical models is still lacking. Models describe physic
Externí odkaz:
https://doaj.org/article/f5f2069f58c44f30822ce2059fa7bcea
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005100 (2017)
Externí odkaz:
https://doaj.org/article/f15161181ec34410a7d5165f1c2caa4f
Autor:
Luca Cardelli
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 26, Iss Proc. DCM 2010, Pp 47-61 (2010)
We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the s
Externí odkaz:
https://doaj.org/article/fc7dffa37abb49a2b0c4a919dc8a2a9a
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 9, Iss Proc. DCM 2009, Pp 73-86 (2009)
We introduce a natural language interface for building stochastic pi calculus models of biological systems. In this language, complex constructs describing biochemical events are built from basic primitives of association, dissociation and transforma
Externí odkaz:
https://doaj.org/article/6ff4dd40c8f84116b567b7f6417b77f2
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 11, p e1003322 (2013)
Achieving a complete understanding of cellular signal transduction requires deciphering the relation between structural and biochemical features of a signaling system and the shape of the signal-response relationship it embeds. Using explicit analyti
Externí odkaz:
https://doaj.org/article/e8cf14fe23284a9896dd98f2576e519a
Publikováno v:
Logical Methods in Computer Science, Vol Volume 8, Issue 4 (2012)
Continuous Markovian Logic (CML) is a multimodal logic that expresses quantitative and qualitative properties of continuous-time labelled Markov processes with arbitrary (analytic) state-spaces, henceforth called continuous Markov processes (CMPs). T
Externí odkaz:
https://doaj.org/article/145557e557734ce9a3523271f48cdd30
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29716 (2012)
DNA replication, mitosis and mitotic exit are critical transitions of the cell cycle which normally occur only once per cycle. A universal control mechanism was proposed for the regulation of mitotic entry in which Cdk helps its own activation throug
Externí odkaz:
https://doaj.org/article/8fbbe216d7a347c69b8832ad8c46fbb9