Distinct Calcium Binding and Structural Properties of Two Centrin Isoforms from Toxoplasma gondii

Autor: Luca Bombardi, Marco Pedretti, Carolina Conter, Paola Dominici, Alessandra Astegno

Publikováno v: Biomolecules, Vol 10, Iss 8, p 1142 (2020)

Centrins are calcium (Ca2+)-binding proteins that have been implicated in several regulatory functions. In the protozoan parasite Toxoplasma gondii, the causative agent of toxoplasmosis, three isoforms of centrin have been identified. While increasin

Externí odkaz: https://doaj.org/article/a2cc94b9a2d44e93954f114ef2db401b

The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii

Autor: Carolina Conter, Filippo Favretto, Paola Dominici, Alessandra Astegno, Adele Di Matteo, Marco Pedretti, Luca Bombardi

Publikováno v: Biochemical journal (Lond., 1984) 478 (2021): 2571–2587. doi:10.1042/BCJ20210295
info:cnr-pdr/source/autori:Conter C.; Bombardi L.; Pedretti M.; Favretto F.; Di Matteo A.; Dominici P.; Astegno A./titolo:The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii/doi:10.1042%2FBCJ20210295/rivista:Biochemical journal (Lond., 1984)/anno:2021/pagina_da:2571/pagina_a:2587/intervallo_pagine:2571–2587/volume:478
Biochemical Journal

Centrins are conserved calcium (Ca2+)-binding proteins typically associated with centrosomes that have been implicated in several biological processes. In Toxoplasma gondii, a parasite that causes toxoplasmosis, three centrin isoforms have been recog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dab3cdd7cc209593f364658163f24c

Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b

Autor: Antonio Coluccia, Romano Silvestri, Gianni Colotti, Adriano Mollica, Valerio Licursi, Luca Bombardi, Cecilia Mannironi, Simone Pippa, Rodolfo Negri, Enrico Cundari, Giuseppe La Regina, Valentina Naccarato

Publikováno v: Molecules, Vol 24, Iss 9, p 1739 (2019)
Molecules (Basel, Online) 24 (2019). doi:10.3390/molecules24091739
info:cnr-pdr/source/autori:Pippa, Simone; Mannironi, Cecilia; Licursi, Valerio; Bombardi, Luca; Colotti, Gianni; Cundari, Enrico; Mollica, Adriano; Coluccia, Antonio; Naccarato, Valentina; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo/titolo:Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B/doi:10.3390%2Fmolecules24091739/rivista:Molecules (Basel, Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:24
Molecules
Volume 24
Issue 9

Background: KDM5 enzymes are H3K4 specific histone demethylases involved in transcriptional regulation and DNA repair. These proteins are overexpressed in different kinds of cancer, including breast, prostate and bladder carcinomas, with positive eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9ad2225513cc86ba45f97a97a0c5b8
http://hdl.handle.net/11573/1266997

Appetite for Destruction

Autor: Luca Bombardieri, Marialucia Amadio

Publikováno v: Documenta Praehistorica, Vol 48 (2021)

Destruction processes are considered ‘time capsules of material culture’ (Driessen 2013) as they freeze a site at one moment of its history providing key evidence for interpreting the archaeological record and reconstructing social, political, cu

Externí odkaz: https://doaj.org/article/058a831a10d942b58aad80267664c457

Tra erudizione ed intelligence : John C. Lawson e Francis B. Welch, Cipro 1899

Autor: Luca Bombardieri, Tommaso Braccini

Publikováno v: Pallas, Vol 97, Pp 221-231 (2015)

Among the few direct and first-hand evidences discussed by John Cuthbert Lawson (1874-1935) in his monumental Modern Greek Folklore and Ancient Greek Religion (1910), one can find an intriguing legend on werewolves attested in Cyprus.While he mention

Externí odkaz: https://doaj.org/article/8fabafbd3d5842869e8b00beedd09f80