Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Luca Beretta"'
Autor:
Silvia Paola Caminiti, Arianna Sala, Leonardo Iaccarino, Luca Beretta, Andrea Pilotto, Luigi Gianolli, Sandro Iannaccone, Giuseppe Magnani, Alessandro Padovani, Luigi Ferini-Strambi, Daniela Perani
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2019)
Abstract Background [18F]FDG-PET hypometabolism patterns are indicative of different neurodegenerative conditions, even from the earliest disease phase. This makes [18F]FDG-PET a valuable tool in the diagnostic workup of neurodegenerative diseases. T
Externí odkaz:
https://doaj.org/article/29c5f5453a644ed2814740c3124991de
Autor:
Salvatore Princiotto, Cecilia Pinna, Luce Micaela Mattio, Francesca Annunziata, Giovanni Luca Beretta, Andrea Pinto, Sabrina Dallavalle
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1012 (2024)
Within the huge class of plant secondary metabolites, resveratrol-derived stilbenoids show wide structural diversity and mediate a great number of biological responses relevant for human health, including cancer prevention and cytotoxicity. Resveratr
Externí odkaz:
https://doaj.org/article/7802c23cfaab4f298f2b546ac6ec1e7a
Autor:
Giovanni Luca Beretta, Desirè Alampi, Cristina Corno, Nives Carenini, Elisabetta Corna, Paola Perego
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 5048 (2024)
Epigenetic alterations my play a role in the aggressive behavior of Non-Small Cell Lung Cancer (NSCLC). Treatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA, vorinostat) has been reported to interfere with the prolif
Externí odkaz:
https://doaj.org/article/dda474037d4e4f939a2447d047f3a3fc
Autor:
Giovanni Luca Beretta
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2054 (2024)
Prostate cancer (PCa) represents the second most diagnosed tumor and the fifth most common cause of cancer death in men globally [...]
Externí odkaz:
https://doaj.org/article/146f68accb4b49af9f949dfda9402d0c
Autor:
Salvatore Princiotto, Loana Musso, Fabrizio Manetti, Valentina Marcellini, Giovanni Maga, Emmanuele Crespan, Cecilia Perini, Nadia Zaffaroni, Giovanni Luca Beretta, Sabrina Dallavalle
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2382-2394 (2022)
Inhibition of c-Src is considered one of the most studied approaches to cancer treatment, with several heterocyclic compounds approved during the last 15 years as chemotherapeutic agents. Starting from the biological evaluation of an in-house collect
Externí odkaz:
https://doaj.org/article/95aeb38bd14c4805af558781c3254a39
Autor:
Michele Dei Cas, Chiara Maura Ciniselli, Elisabetta Vergani, Emilio Ciusani, Mariachiara Aloisi, Valeria Duroni, Paolo Verderio, Riccardo Ghidoni, Rita Paroni, Paola Perego, Giovanni Luca Beretta, Laura Gatti, Monica Rodolfo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1558 (2024)
Dysfunctions of lipid metabolism are associated with tumor progression and treatment resistance of cutaneous melanoma. BRAF/MEK inhibitor resistance is linked to alterations of melanoma lipid pathways. We evaluated whether a specific lipid pattern ch
Externí odkaz:
https://doaj.org/article/e6d34927b8cf4d9d9f361f871472e631
Autor:
Salvatore Princiotto, Maria Karelou, Rachel Ioannidi, Giovanni Luca Beretta, Nadia Zaffaroni, Roberto Artali, Ioannis K. Kostakis, Stefania Mazzini, Sabrina Dallavalle
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14346 (2023)
Novel amino-substituted pyridoquinazolinone derivatives have been designed and synthesized as potential c-MYC G-quadruplex (G4) ligands, employing an efficient methodology. All the new compounds exhibited moderate to good antiproliferative activity a
Externí odkaz:
https://doaj.org/article/514984efa5314c34b8e811b7a291f9ef
Autor:
Giovanni Luca Beretta
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14486 (2022)
The attractiveness of the nanomaterials research field has persisted [...]
Externí odkaz:
https://doaj.org/article/fdfe326546f741b294a6171477c9a12a
Autor:
Giovanni Luca Beretta, Nadia Zaffaroni
Publikováno v:
Cells, Vol 11, Iss 7, p 1221 (2022)
Necroptosis is a programmed form of necrosis characterized by mitochondrial alterations and plasma membrane permeabilization resulting in the release of cytoplasmic content into extracellular space, and leading to inflammatory reactions. Besides its
Externí odkaz:
https://doaj.org/article/7a4a5488ef254812a0556c579ed01d01
Autor:
Nadia Zaffaroni, Giovanni Luca Beretta
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1785 (2021)
Ferroptosis is a regulated cell death mechanism holding promise for anticancer therapy. Numerous small molecules inducing ferroptosis have been reported thus far. However, these compounds suffer from important drawbacks including poor solubility, sys
Externí odkaz:
https://doaj.org/article/77e10f2cd58842fdaa46bd22e0040462